(Q37936683)

25 August 2017

1 reference

title

Biology of cardiac sodium channel Nav1.5 expression (English)

1 reference

25 August 2017

Melvin M Evers

2

0 references

author name string

Martin B Rook

series ordinal

1

1 reference

25 August 2017

Marc A Vos

series ordinal

3

1 reference

25 August 2017

Marti F A Bierhuizen

series ordinal

4

1 reference

25 August 2017

21 September 2011

1 reference

25 August 2017

Cardiovascular Research

1 reference

25 August 2017

93

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25 August 2017

1

1 reference

25 August 2017

12-23

1 reference

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels

25 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

A mutation in telethonin alters Nav1.5 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Voltage-gated Sodium Channel Activity Promotes Cysteine Cathepsin-dependent Invasiveness and Colony Growth of Human Cancer Cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

The Na+ channel inactivation gate is a molecular complex: a novel role of the COOH-terminal domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Sodium channel mutations and arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Cardiac sodium channel Na(v)1.5 and interacting proteins: Physiology and pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Syntrophin gamma 2 regulates SCN5A gating by a PDZ domain-mediated interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

alpha-1-syntrophin mutation and the long-QT syndrome: a disease of sodium channel disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Cardiac sodium channel Nav1.5 is regulated by a multiprotein complex composed of syntrophins and dystrophin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Identification of a Conserved Ankyrin-binding Motif in the Family of Sodium Channel α Subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Nav1.5 E1053K mutation causing Brugada syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Voltage-gated Nav channel targeting in the heart requires an ankyrin-G dependent cellular pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Identification of a new co-factor, MOG1, required for the full function of cardiac sodium channel Nav 1.5

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Modulation of the cardiac sodium channel Nav1.5 by fibroblast growth factor homologous factor 1B

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Crystal Structure of a Fibroblast Growth Factor Homologous Factor (FHF) Defines a Conserved Surface on FHFs for Binding and Modulation of Voltage-gated Sodium Channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Cardiac sodium channel Na(v)1.5 interacts with and is regulated by the protein tyrosine phosphatase PTPH1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

A calcium sensor in the sodium channel modulates cardiac excitability

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Isoform-specific modulation of voltage-gated Na(+) channels by calmodulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Calmodulin mediates Ca2+ sensitivity of sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Modulation of skeletal and cardiac voltage-gated sodium channels by calmodulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

A double tyrosine motif in the cardiac sodium channel domain III-IV linker couples calcium-dependent calmodulin binding to inactivation gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Functional Interactions between Distinct Sodium Channel Cytoplasmic Domains through the Action of Calmodulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Solution NMR structure of Apo-calmodulin in complex with the IQ motif of human cardiac sodium channel NaV1.5

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Constitutive CaMKII activity regulates Na+ channel in rat ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Nav1.5-dependent persistent Na+ influx activates CaMKII in rat ventricular myocytes and N1325S mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Regulation of the cardiac voltage-gated Na+ channel (H1) by the ubiquitin-protein ligase Nedd4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

14-3-3 is a regulator of the cardiac voltage-gated sodium channel Nav1.5

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Loss of plakophilin-2 expression leads to decreased sodium current and slower conduction velocity in cultured cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Localization of cardiac sodium channels in caveolin-rich membrane domains: regulation of sodium current amplitude

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Mutant caveolin-3 induces persistent late sodium current and is associated with long-QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

GPD1L links redox state to cardiac excitability by PKC-dependent phosphorylation of the sodium channel SCN5A

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Molecular and functional characterization of novel glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) mutations in sudden infant death syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Cell membrane expression of cardiac sodium channel Na(v)1.5 is modulated by alpha-actinin-2 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Characterization of sodium channel alpha- and beta-subunits in rat and mouse cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Mutations in sodium channel β1- and β2-subunits associated with atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Loss-of-function mutation of the SCN3B-encoded sodium channel {beta}3 subunit associated with a case of idiopathic ventricular fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

SCN4B-encoded sodium channel beta4 subunit in congenital long-QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Cardiac sodium channel overlap syndromes: different faces of SCN5A mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Hallmarks of ion channel gene expression in end-stage heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Chronic heart failure slows late sodium current in human and canine ventricular myocytes: implications for repolarization variability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Increased late sodium current in myocytes from a canine heart failure model and from failing human heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Structure and function of splice variants of the cardiac voltage-gated sodium channel Na(v)1.5

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Tandem promoters and developmentally regulated 5'- and 3'-mRNA untranslated regions of the mouse Scn5a cardiac sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Human heart failure is associated with abnormal C-terminal splicing variants in the cardiac sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Alternative promoter usage and splicing of the human SCN5A gene contribute to transcript heterogeneity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

A ubiquitous splice variant and a common polymorphism affect heterologous expression of recombinant human SCN5A heart sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Novel isoforms of the sodium channels Nav1.8 and Nav1.5 are produced by a conserved mechanism in mouse and rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Modulation of Nav1.5 channel function by an alternatively spliced sequence in the DII/DIII linker region.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Tetrodotoxin-resistant Na+ channels in human neuroblastoma cells are encoded by new variants of Nav1.5/SCN5A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Mouse heart Na+ channels: primary structure and function of two isoforms and alternatively spliced variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Analysis of four novel variants of Nav1.5/SCN5A cloned from the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

A novel polyclonal antibody specific for the Na(v)1.5 voltage-gated Na(+) channel 'neonatal' splice form

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Primary structure and functional expression of the human cardiac tetrodotoxin-insensitive voltage-dependent sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Effects of III-IV linker mutations on human heart Na+ channel inactivation gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

A common human SCN5A polymorphism modifies expression of an arrhythmia causing mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Alternative splicing of the cardiac sodium channel creates multiple variants of mutant T1620K channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Distinct subcellular localization of different sodium channel alpha and beta subunits in single ventricular myocytes from mouse heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

An unexpected role for brain-type sodium channels in coupling of cell surface depolarization to contraction in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Distribution of proteins implicated in excitation-contraction coupling in rat ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Tissue distribution and subcellular localization of the cardiac sodium channel during mouse heart development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Molecular identity of the late sodium current in adult dog cardiomyocytes identified by Nav1.5 antisense inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Cloning and initial characterization of the human cardiac sodium channel (SCN5A) promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Informatic and functional approaches to identifying a regulatory region for the cardiac sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

NF-kappaB-dependent transcriptional regulation of the cardiac scn5a sodium channel by angiotensin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Alternative splicing of Nav1.5: an electrophysiological comparison of 'neonatal' and 'adult' isoforms and critical involvement of a lysine residue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Glycosylation influences voltage-dependent gating of cardiac and skeletal muscle sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Differential sialylation modulates voltage-gated Na+ channel gating throughout the developing myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Role of sodium channel deglycosylation in the genesis of cardiac arrhythmias in heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Isoform-specific effects of sialic acid on voltage-dependent Na+ channel gating: functional sialic acids are localized to the S5-S6 loop of domain I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Regulated and aberrant glycosylation modulate cardiac electrical signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Isoform diversity and modulation of sodium channels by protein kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Modulation of the human cardiac sodium channel alpha-subunit by cAMP-dependent protein kinase and the responsible sequence domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Modulation of rat cardiac sodium channel by the stimulatory G protein alpha subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Activation of protein kinase A modulates trafficking of the human cardiac sodium channel in Xenopus oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Phosphorylation and putative ER retention signals are required for protein kinase A-mediated potentiation of cardiac sodium current

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Quantitation of protein kinase A-mediated trafficking of cardiac sodium channels in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

cAMP-dependent phosphorylation of two sites in the alpha subunit of the cardiac sodium channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Modulation of cardiac Na+ channels expressed in a mammalian cell line and in ventricular myocytes by protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Phosphorylation of S1505 in the cardiac Na+ channel inactivation gate is required for modulation by protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Functional effects of protein kinase C activation on the human cardiac Na+ channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Conventional protein kinase C isoforms and cross-activation of protein kinase A regulate cardiac Na+ current

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Cardiac Na+ current regulation by pyridine nucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Modulation of Na+ current inactivation by stimulation of protein kinase C in cardiac cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Slowing of the inactivation of voltage-dependent sodium channels by staurosporine, the protein kinase C inhibitor, in rabbit atrial myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Modulation of cardiac sodium channel isoform by cyclic AMP dependent protein kinase does not depend on phosphorylation of serine 1504 in the cytosolic loop interconnecting transmembrane domains III and IV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Na+ channel regulation by Ca2+/calmodulin and Ca2+/calmodulin-dependent protein kinase II in guinea-pig ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

An EF-hand in the sodium channel couples intracellular calcium to cardiac excitability

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Calcium-dependent regulation of the voltage-gated sodium channel hH1: intrinsic and extrinsic sensors use a common molecular switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Solution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Intracellular calcium modulation of voltage-gated sodium channels in ventricular myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Reactive oxygen species-activated Ca/calmodulin kinase IIδ is required for late I(Na) augmentation leading to cellular Na and Ca overload.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Calcium-dependent regulation of voltage-gated sodium channels in cardiac myocytes: just the beginning?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Inhibition of fast sodium current in rabbit ventricular myocytes by protein tyrosine kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Modulation of the cardiac sodium channel NaV1.5 by Fyn, a Src family tyrosine kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Regulation of caveolar cardiac sodium current by a single Gsalpha histidine residue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Being there: cellular targeting of voltage-gated sodium channels in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Alpha1-syntrophin mutations identified in sudden infant death syndrome cause an increase in late cardiac sodium current

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Phenotypical manifestations of mutations in the genes encoding subunits of the cardiac sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

The promiscuous nature of the cardiac sodium current

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Voltage-gated Na+ channel transcript patterns in the mammalian heart are species-dependent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

A mutation in the beta 3 subunit of the cardiac sodium channel associated with Brugada ECG phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Functional dominant-negative mutation of sodium channel subunit gene SCN3B associated with atrial fibrillation in a Chinese GeneID population

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

The cardiac sodium channel is post-translationally modified by arginine methylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

The crystal structure of a voltage-gated sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

The sodium channel Nav1.5a is the predominant isoform expressed in adult mouse dorsal root ganglia and exhibits distinct inactivation properties from the full-length Nav1.5 channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVR252

21 January 2018

Identifiers

DOI

10.1093/CVR/CVR252

1 reference

release_ctat6s4a6ndl5nrvigy4baai3y

25 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ctat6s4a6ndl5nrvigy4baai3y

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference