(Q37937423)

25 August 2017

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title

Aminoacyl-tRNA synthetases and tumorigenesis: more than housekeeping (English)

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25 August 2017

Sunghoon Kim

1

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25 August 2017

Sungyong You

series ordinal

2

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25 August 2017

Daehee Hwang

series ordinal

3

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25 August 2017

language of work or name

English

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publication date

23 September 2011

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25 August 2017

Nature Reviews Cancer

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25 August 2017

11

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25 August 2017

10

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25 August 2017

708-718

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https://scigraph.springernature.com/pub.10.1038/nrc3124

25 August 2017

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cites work

New functions of aminoacyl-tRNA synthetases beyond translation

1 reference

Functional expansion of aminoacyl-tRNA synthetases and their interacting factors: new perspectives on housekeepers

31 March 2020

1 reference

Aminoacyl tRNA synthetases and their connections to disease

31 March 2020

1 reference

Implication of leucyl-tRNA synthetase 1 (LARS1) over-expression in growth and migration of lung cancer cells detected by siRNA targeted knock-down analysis

31 March 2020

1 reference

Proteomic interrogation of androgen action in prostate cancer cells reveals roles of aminoacyl tRNA synthetases

31 March 2020

1 reference

Elevated methionine-tRNA synthetase activity in human colon cancer

31 March 2020

1 reference

Elevated tRNA(iMet) synthesis can drive cell proliferation and oncogenic transformation

31 March 2020

1 reference

The protooncogene CHOP/GADD153, involved in growth arrest and DNA damage response, is amplified in a subset of human sarcomas

31 March 2020

1 reference

Characterization of the 12q13-15 amplicon in soft tissue tumors

31 March 2020

1 reference

Cytogenetic and molecular genetic analysis of a pediatric pleomorphic sarcoma reveals similarities to adult malignant fibrous histiocytoma

31 March 2020

1 reference

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription

31 March 2020

1 reference

Evidence for instability of mRNAs containing AUUUA motifs mediated through translation-dependent assembly of a > 20S degradation complex

31 March 2020

1 reference

CHOP/GADD153 and methionyl-tRNA synthetase (MetRS) genes overlap in a conserved region that controls mRNA stability

31 March 2020

1 reference

Frameshift Mutation of MARS Gene Encoding an Aminoacyl-tRNA Synthetase in Gastric and Colorectal Carcinomas with Microsatellite Instability

31 March 2020

1 reference

Rescuing the function of mutant p53.

31 March 2020

1 reference

Orchestrating the unfolded protein response in health and disease

31 March 2020

1 reference

The role of the unfolded protein response in tumour development: friend or foe?

31 March 2020

1 reference

Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration

31 March 2020

1 reference

Analysis of the 5' region of PMS2 reveals heterogeneous transcripts and a novel overlapping gene

31 March 2020

1 reference

Hierarchical network between the components of the multi-tRNA synthetase complex: implications for complex formation.

31 March 2020

1 reference

Macromolecular complexes as depots for releasable regulatory proteins.

31 March 2020

1 reference

Macromolecular assemblage of aminoacyl-tRNA synthetases: identification of protein-protein interactions and characterization of a core protein

31 March 2020

1 reference

The p18 component of the multisynthetase complex shares a protein motif with the beta and gamma subunits of eukaryotic elongation factor 1

31 March 2020

1 reference

p38 is essential for the assembly and stability of macromolecular tRNA synthetase complex: implications for its physiological significance

31 March 2020

1 reference

Precursor of pro-apoptotic cytokine modulates aminoacylation activity of tRNA synthetase

31 March 2020

1 reference

Mutations of two PMS homologues in hereditary nonpolyposis colon cancer

31 March 2020

1 reference

Lysyl-tRNA synthetase interacts with EF1alpha, aspartyl-tRNA synthetase and p38 in vitro

31 March 2020

1 reference

Solution structure and p43 binding of the p38 leucine zipper motif: coiled-coil interactions mediate the association between p38 and p43

31 March 2020

1 reference

Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation

31 March 2020

1 reference

A sequence-specific, single-strand binding protein activates the far upstream element of c-myc and defines a new DNA-binding motif

31 March 2020

1 reference

The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators

31 March 2020

1 reference

AIMP2 promotes TNFalpha-dependent apoptosis via ubiquitin-mediated degradation of TRAF2.

31 March 2020

1 reference

TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2

31 March 2020

1 reference

AIMP2/p38, the scaffold for the multi-tRNA synthetase complex, responds to genotoxic stresses via p53

31 March 2020

1 reference

Mdm2 links genotoxic stress and metabolism to p53.

31 March 2020

1 reference

Multidirectional tumor-suppressive activity of AIMP2/p38 and the enhanced susceptibility of AIMP2 heterozygous mice to carcinogenesis

31 March 2020

1 reference

Cancer-associated splicing variant of tumor suppressor AIMP2/p38: pathological implication in tumorigenesis

31 March 2020

1 reference

The haploinsufficient tumor suppressor p18 upregulates p53 via interactions with ATM/ATR

31 March 2020

1 reference

AIMP3 haploinsufficiency disrupts oncogene-induced p53 activation and genomic stability.

31 March 2020

1 reference

Determination of three-dimensional structure and residues of the novel tumor suppressor AIMP3/p18 required for the interaction with ATM

31 March 2020

1 reference

Downregulation of lamin A by tumor suppressor AIMP3/p18 leads to a progeroid phenotype in mice.

31 March 2020

1 reference

Dual roles of lineage restricted transcription factors: the case of MITF in melanocytes

31 March 2020

1 reference

Suppression of microphthalmia transcriptional activity by its association with protein kinase C-interacting protein 1 in mast cells

31 March 2020

1 reference

Does the ribosome translate cancer?

31 March 2020

1 reference

Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth.

31 March 2020

1 reference

Nucleolar localization of human methionyl-tRNA synthetase and its role in ribosomal RNA synthesis

31 March 2020

1 reference

ASK1 mediates apoptotic cell death induced by genotoxic stress.

31 March 2020

1 reference

Glutamine-dependent antiapoptotic interaction of human glutaminyl-tRNA synthetase with apoptosis signal-regulating kinase 1

31 March 2020

1 reference

A multifunctional repeated motif is present in human bifunctional tRNA synthetase

31 March 2020

1 reference

Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation

31 March 2020

1 reference

A stress-responsive RNA switch regulates VEGFA expression.

31 March 2020

1 reference

Phosphorylation of glutamyl-prolyl tRNA synthetase by cyclin-dependent kinase 5 dictates transcript-selective translational control

31 March 2020

1 reference

The GAIT system: a gatekeeper of inflammatory gene expression.

31 March 2020

1 reference

Transcriptional regulation of the interferon-gamma-inducible tryptophanyl-tRNA synthetase includes alternative splicing

31 March 2020

1 reference

Alternative processing of the tryptophanyl-tRNA synthetase mRNA from interferon-treated human cells

31 March 2020

1 reference

A human aminoacyl-tRNA synthetase as a regulator of angiogenesis

31 March 2020

1 reference

Evidence for annexin II-S100A10 complex and plasmin in mobilization of cytokine activity of human TrpRS

31 March 2020

1 reference

VE-cadherin links tRNA synthetase cytokine to anti-angiogenic function.

31 March 2020

1 reference

A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase

31 March 2020

1 reference

The prognostic significance of tryptophanyl-tRNA synthetase in colorectal cancer

31 March 2020

1 reference

Two distinct cytokines released from a human aminoacyl-tRNA synthetase

31 March 2020

1 reference

Induction of angiogenesis by a fragment of human tyrosyl-tRNA synthetase

31 March 2020

1 reference

Crystal structure of a human aminoacyl-tRNA synthetase cytokine

31 March 2020

1 reference

The novel fragment of tyrosyl tRNA synthetase, mini-TyrRS, is secreted to induce an angiogenic response in endothelial cells

31 March 2020

1 reference

Highly differentiated motifs responsible for two cytokine activities of a split human tRNA synthetase

31 March 2020

1 reference

Human lysyl-tRNA synthetase is secreted to trigger proinflammatory response

31 March 2020

1 reference

Anti-aminoacyl tRNA synthetase immune responses: insights into the pathogenesis of the idiopathic inflammatory myopathies

31 March 2020

1 reference

A cofactor of tRNA synthetase, p43, is secreted to up-regulate proinflammatory genes

31 March 2020

1 reference

Antitumor activity and pharmacokinetic properties of ARS-interacting multi-functional protein 1 (AIMP1/p43).

31 March 2020

1 reference

Dose-dependent biphasic activity of tRNA synthetase-associating factor, p43, in angiogenesis.

31 March 2020

1 reference

The novel cytokine p43 induces IL-12 production in macrophages via NF-kappaB activation, leading to enhanced IFN-gamma production in CD4+ T cells

31 March 2020

1 reference

AIMP1/p43 protein induces the maturation of bone marrow-derived dendritic cells with T helper type 1-polarizing ability

31 March 2020

1 reference

Gene transfer of AIMP1 and B7.1 into epitope-loaded, fibroblasts induces tumor-specific CTL immunity, and prolongs the survival period of tumor-bearing mice

31 March 2020

1 reference

Endothelial monocyte-activating polypeptide-II and its functions in (patho)physiological processes

31 March 2020

1 reference

Interaction of the C-terminal domain of p43 and the alpha subunit of ATP synthase. Its functional implication in endothelial cell proliferation

31 March 2020

1 reference

Role of ATP synthase alpha subunit in low-dose endothelial monocyte-activating polypeptide-II-induced opening of the blood-tumor barrier

31 March 2020

1 reference

Endothelial-monocyte-activating polypeptide II induces migration of endothelial progenitor cells via the chemokine receptor CXCR3

31 March 2020

1 reference

NCBI GEO: archive for high-throughput functional genomic data

31 March 2020

1 reference

ArrayExpress--a public database of microarray experiments and gene expression profiles

31 March 2020

1 reference

Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies

31 March 2020

1 reference

A data integration methodology for systems biology

31 March 2020

1 reference

CanGEM: mining gene copy number changes in cancer

31 March 2020

1 reference

The landscape of somatic copy-number alteration across human cancers

31 March 2020

1 reference

PHOSIDA 2011: the posttranslational modification database

31 March 2020

1 reference

PhosphoSite: A bioinformatics resource dedicated to physiological protein phosphorylation

31 March 2020

1 reference

Exploration of biological network centralities with CentiBiN.

31 March 2020

1 reference

Transitive functional annotation by shortest-path analysis of gene expression data

31 March 2020

1 reference

A gene-coexpression network for global discovery of conserved genetic modules

31 March 2020

1 reference

Coexpression analysis of human genes across many microarray data sets

31 March 2020

1 reference

Geometric interpretation of gene coexpression network analysis

31 March 2020

1 reference

Statistical mechanics of complex networks

31 March 2020

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Identification of gp96 as a novel target for treatment of autoimmune disease in mice

31 March 2020

1 reference

Antitumor effects of EMAP II against pancreatic cancer through inhibition of fibronectin-dependent proliferation.

31 March 2020

1 reference

Translational control in cancer.

31 March 2020

1 reference

Glycyl tRNA synthetase mutations in Charcot-Marie-Tooth disease type 2D and distal spinal muscular atrophy type V.

31 March 2020

1 reference

Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy

31 March 2020

1 reference

The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: linking protein biosynthesis and neurodegeneration.

31 March 2020

1 reference

Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death.

31 March 2020

1 reference

Pelizaeus-Merzbacher-like disease caused by AIMP1/p43 homozygous mutation.

31 March 2020

1 reference

MSC p43 required for axonal development in motor neurons.

31 March 2020

1 reference

Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene

31 March 2020

1 reference

Inactivation of LARS2, located at the commonly deleted region 3p21.3, by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma

31 March 2020

1 reference

The balance between pre- and post-transfer editing in tRNA synthetases

31 March 2020

1 reference

Dinucleoside polyphosphates-friend or foe?

31 March 2020

1 reference

Chapter 1: The physiological role of lysyl tRNA synthetase in the immune system.

31 March 2020

1 reference

The function of lysyl-tRNA synthetase and Ap4A as signaling regulators of MITF activity in FcepsilonRI-activated mast cells

31 March 2020

1 reference

Aminoacyl-tRNA synthetase-interacting multifunctional proteins (AIMPs): a triad for cellular homeostasis

31 March 2020

1 reference

12 December 2020

Antitumor activity of the novel human cytokine AIMP1 in an in vivo tumor model.

1 reference

12 December 2020

Enhancing cytotoxic agent activity in experimental pancreatic cancer through EMAP II combination therapy

1 reference

12 December 2020

Endothelial monocyte-activating polypeptide II. A novel tumor-derived polypeptide that activates host-response mechanisms

1 reference

12 December 2020

Scanning mutagenesis of interleukin-8 identifies a cluster of residues required for receptor binding.

1 reference

12 December 2020

Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets.

1 reference

12 December 2020

Mitochondrial gene mutations in the tRNA(Leu(UUR)) region and diabetes: prevalence and clinical phenotypes in Japan

1 reference

12 December 2020

Antitumor effect of endothelial monocyte-activating polypeptide-II on human prostate adenocarcinoma in mouse xenograft model.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRC3124

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Dimensions Publication ID

25 August 2017

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1 reference