(Q37944769)

25 August 2017

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title

Clinical pharmacokinetics of prednisone and prednisolone (English)

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25 August 2017

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Frey BM

1

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PubMed ID

2199128

25 August 2017

Frey FJ

series ordinal

2

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25 August 2017

1 August 1990

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Clinical Pharmacokinetics

25 August 2017

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25 August 2017

19

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25 August 2017

2

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25 August 2017

126-146

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https://scigraph.springernature.com/pub.10.2165/00003088-199019020-00003

25 August 2017

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cites work

Conversion of cortisone to cortisol and prednisone to prednisolone

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12 December 2020

Effect of liver function on the metabolism of prednisone and prednisolone in humans

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12 December 2020

Structure-activity relationships in the effects of 1-alkylimidazoles on microsomal oxidation in vitro and in vivo

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12 December 2020

Effects of enzyme induction on metabolism of prednisolone. Clinical and laboratory study

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12 December 2020

Prednisolone clearance at steady state in man

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12 December 2020

Plasma prednisolone levels in man following administration in plain and enteric-coated forms

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12 December 2020

Simultaneous measurement of prednisone, prednisolone and 6 beta-hydroxyprednisolone in urine by high-performance liquid chromatography coupled with a radioactivity detector

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12 December 2020

Phenytoin modulates the pharmacokinetics of prednisolone and the pharmacodynamics of prednisolone as assessed by the inhibition of the mixed lymphocyte reaction in humans

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12 December 2020

Altered plasma protein-binding of prednisolone in patients with the nephrotic syndrome

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12 December 2020

The influence of uremia on pharmacokinetics and protein binding of prednisolone

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12 December 2020

Altered prednisolone pharmacokinetics in patients treated with rifampicin

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12 December 2020

Bioavailability of prednisolone in patients with intestinal malabsorption: the importance of measuring serum protein-binding

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12 December 2020

Prednisolone disposition in obese men

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12 December 2020

Comparative serum pharmacokinetics of prednisone and prednisolone methylsulfobenzoate after oral administration

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12 December 2020

Daily and alternate-day corticosteroid regimens in treatment of giant cell arteritis: comparison in a prospective study

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12 December 2020

Impairment of prednisolone disposition in women taking oral contraceptives or conjugated estrogens.

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12 December 2020

Effect of prednisone dose spacing on plasma lipids.

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12 December 2020

Serum cyclosporin levels, hepatic drug metabolism and renal tubulotoxicity

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12 December 2020

A single dose of azathioprine does not affect the pharmacokinetics of prednisolone following oral prednisone

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12 December 2020

Prevention of peptic ulceration during corticosteroid therapy.

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12 December 2020

The macromolecular binding of prednisone in plasma of healthy volunteers including pregnant women and oral contraceptive users

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12 December 2020

Corticosteroid analysis in biological fluids by high-performance liquid chromatography

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12 December 2020

Prednisolone pharmacokinetics compared between night and day in asthmatic and normal subjects

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12 December 2020

Influence of prednisolone on antipyrine and chloramphenicol disposition in rabbits

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12 December 2020

Disposition of total and unbound prednisolone in renal transplant patients receiving anticonvulsants

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12 December 2020

The dose-dependent systemic availability of prednisone: one reason for the reduced biological effect of alternate-day prednisone

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12 December 2020

The nonlinear pharmacokinetics of prednisone and prednisolone. II. Plasma protein binding of prednisone and prednisolone in rabbit and human plasma

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12 December 2020

Kinetics of prednisolone and endogenous cortisol suppression in the elderly

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12 December 2020

Concentration-dependent effects of prednisolone on lymphocyte subsets and mixed lymphocyte culture in humans

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12 December 2020

Binding of prednisolone to alpha 1-acid glycoprotein

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12 December 2020

The effect of cyclosporine on the pharmacokinetics of prednisolone in renal transplant patients

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12 December 2020

Absorption of prednisolone in patients with Crohn's disease

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12 December 2020

Prednisone or prednisolone for the treatment of chronic active hepatitis? A comparison of plasma availability

1 reference

12 December 2020

Comparison of prednisolone kinetics in patients receiving daily or alternate-day prednisone for asthma

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12 December 2020

Urinary 6 beta-hydroxyprednisolone excretion indicates enhanced prednisolone catabolism

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12 December 2020

Prednisone side-effects and serum-protein levels. A collaborative study

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12 December 2020

Clinical Pharmacokinetics of Prednisone and Prednisolone

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12 December 2020

Effect of smoking on prednisone, prednisolone, and dexamethasone pharmacokinetics

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12 December 2020

[Transcortin concentrations in the plasma of normal persons and patients with kidney and liver diseases]

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12 December 2020

Serum prednisolone levels in Crohn's disease and coeliac disease following oral prednisolone administration

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12 December 2020

Prednisolone absorption in acute colitis

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12 December 2020

Metabolic clearance rates and interconversion of cortisol and cortisone

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12 December 2020

Pharmacokinetics and protein binding of prednisolone in patients with nephrotic syndrome and patients undergoing hemodialysis

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12 December 2020

Prednisolone disposition in cushingoid and noncushingoid kidney transplant patients

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12 December 2020

Pharmacokinetics and pharmacodynamics of three different prednisolone prodrugs: effect on circulating lymphocyte subsets and function

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12 December 2020

Effects of aging and liver disease on disposition of lorazepam

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12 December 2020

The effects of thyroxin administration on the enzymic reduction of delta 4-3-ketosteroids

1 reference

12 December 2020

Inhibition of prednisolone metabolism by cyclosporine in kidney-transplanted patients

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12 December 2020

Non-absorption of enteric-coated prednisolone. Normal absorption of non-enteric-coated prednisolone in a patient with Crohn's disease and massive intestinal resection

1 reference

12 December 2020

Corticosteroids in liver disease: Studies on the biological conversion of prednisone to prednisolone and plasma protein binding

1 reference

12 December 2020

Altered metabolism and decreased efficacy of prednisolone and prednisone in patients with hyperthyroidism

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12 December 2020

Prednisolone disposition and protein binding in oral contraceptive users

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12 December 2020

The adverse effect of anticonvulsant therapy on renal allograft survival. A preliminary report

1 reference

12 December 2020

Dose-dependent actions of thyroxine on hepatic drug metabolism in male and female rats

1 reference

12 December 2020

Immunosuppressive activity of prednisone and prednisolone and their metabolic interconversion in the mixed lymphocyte reaction

1 reference

12 December 2020

Kinetics and Interconversion of Prednisolone and Prednisone Studied with New Radioimmunoassays

1 reference

12 December 2020

Hypoactivity of cytochrome P-450 after triacetyloleandomycin administration

1 reference

12 December 2020

The effect of altered prednisolone kinetics in patients with the nephrotic syndrome and in women taking oral contraceptive steroids on human mixed lymphocyte cultures

1 reference

12 December 2020

Evidence that cyclosporine does not affect the metabolism of prednisolone after renal transplantation

1 reference

12 December 2020

Prednisolone pharmacokinetics in cushingoid and non-cushingoid kidney transplant patients

1 reference

12 December 2020

Liquid-chromatographic measurement of endogenous and exogenous glucocorticoids in plasma

1 reference

12 December 2020

Pharmacokinetics of 3 prednisolone prodrugs. Evidence of therapeutic inequivalence in renal transplant patients with rejection

1 reference

12 December 2020

Pharmacokinetic-pharmacodynamic modeling of prednisolone-induced lymphocytopenia in man

1 reference

12 December 2020

Prednisolone and methylprednisolone kinetics in children receiving anticonvulsant therapy

1 reference

12 December 2020

Dose-dependent prednisolone kinetics

1 reference

12 December 2020

Prednisone for chronic active liver disease: pharmacokinetics, including conversion to prednisolone

1 reference

12 December 2020

[Systemic availability of prednisolone following oral administration of prednisone]

1 reference

12 December 2020

Effectiveness of prednisolone during phenytoin therapy

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12 December 2020

Corticosteroid Pharmacokinetics in Liver Disease

1 reference

12 December 2020

Effects of azole antifungals in vitro on host/parasite interactions relevant to Candida infections.

1 reference

12 December 2020

Enhanced prednisolone elimination: a possible cause for failure of glucocorticoid therapy in Graves' ophthalmopathy

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12 December 2020

Effect of ketoconazole on hepatic oxidative drug metabolism

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12 December 2020

Cortisol does not inhibit prednisolone clearance

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12 December 2020

The metabolism of 1-dehydro-steroids in man: isolation of 6 urinary products following the administration of 11beta, 17alpha, 21-trihydroxy-1, 4-pregnadiene-3, 20-dione

1 reference

12 December 2020

Diurnal variation in prednisolone kinetics

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12 December 2020

Rifampicin-induced non-responsiveness to corticosteroid treatment in nephrotic syndrome

1 reference

12 December 2020

The Absence of Effect of Azathioprine on Prednisolone Pharmacokinetics Following Maintenance Prednisone Doses in Kidney Transplant Patients

1 reference

12 December 2020

Pharmacokinetics of prednisolone and endogenous hydrocortisone levels in cushingoid and non-cushingoid patients

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12 December 2020

Pharmacokinetic interaction of contraceptive steroids with prednisone and prednisolone

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12 December 2020

Marked alterations in dose-dependent prednisolone kinetics in women taking oral contraceptives

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12 December 2020

Effect of inflammatory bowel disease on absorption and disposition of prednisolone

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12 December 2020

Rifampicin reduces effectiveness and bioavailability of prednisolone.

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12 December 2020

Concurrent administration of cimetidine and enteric-coated prednisolone: effect on plasma levels of prednisolone

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12 December 2020

Alterations in prednisolone disposition as a result of time of administration, gender and dose

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12 December 2020

Ketoconazole blocks adrenal steroidogenesis by inhibiting cytochrome P450-dependent enzymes

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12 December 2020

Decreased Clearance of Prednisolone, a Factor in the Development of Corticosteroid Side Effects

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12 December 2020

Influence of thyroid function on the in vivo cortisol ⇌ cortisone equilibrium in man

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12 December 2020

Alterations in prednisolone disposition as a result of oral contraceptive use and dose

1 reference

12 December 2020

Comparison of daily and alternate-day prednisone during chronic maintenance therapy: a controlled crossover study

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12 December 2020

Lack of effect of sucralfate on prednisone bioavailability

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12 December 2020

Endogenous hydrocortisone, a possible factor contributing to the genesis of cushingoid habitus in patients on prednisone.

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12 December 2020

Oral prednisone for chronic active liver disease: dose responses and bioavailability studies

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12 December 2020

Biochemistry, molecular biology, and physiology of the glucocorticoid receptor

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12 December 2020

Interaction of rifampin and glucocorticoids. Adverse effect on renal allograft function

1 reference

12 December 2020

The effect of cortisol, progesterone, and transcortin on phytohemagglutinin-stimulated human blood mononuclear cells and their interplay

1 reference

12 December 2020

Plasma prednisolone levels and adrenocortical responsiveness after administration of prednisolone-21-phosphate as a retention enema

1 reference

12 December 2020

The effects of age and liver disease on the disposition and elimination of diazepam in adult man

1 reference

12 December 2020

Variation in plasma prednisolone concentrations in renal transplant recipients given enteric-coated prednisolone

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12 December 2020

Effect of age and parenchymal liver disease on the disposition and elimination of chlordiazepoxide (librium).

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12 December 2020

Nonlinear plasma protein binding and haemodialysis clearance of prednisolone.

1 reference

12 December 2020

Plasma protein binding interaction of prednisone and prednisolone

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12 December 2020

Prednisolone concentration-effect relations in humans and the influence of plasma hydrocortisone

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12 December 2020

Prednisolone pharmacodynamics assessed by inhibition of the mixed lymphocyte reaction

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12 December 2020

Pharmacokinetics and bioavailability of prednisone and prednisolone in healthy volunteers and patients: a review

1 reference

12 December 2020

Impaired conversion of prednisone to prednisolone in patients with liver cirrhosis

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12 December 2020

Inactivity in vivo of transcortin-bound cortisol

1 reference

12 December 2020

Dose dependent pharmacokinetics of prednisone and prednisolone in man

1 reference

12 December 2020

Potentiation of the biologic effect of administered cortisol by estrogen treatment

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12 December 2020

Effects of cimetidine and ranitidine on the conversion of prednisone to prednisolone

1 reference

12 December 2020

Prednisolone clearance at steady state in dogs.

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12 December 2020

The enzymatic reduction of delta 4-3-ketosteroids

1 reference

12 December 2020

Therapeutic benefits from a poorly absorbed prednisolone enema in distal colitis

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12 December 2020

Steroid-specific and anticonvulsant interaction aspects of troleandomycin-steroid therapy

1 reference

12 December 2020

The effect of prednisone and hydrocortisone on the plasma protein binding of prednisolone in man

1 reference

12 December 2020

Impact of ketoconazole on the metabolism of prednisolone

1 reference

12 December 2020

Clinical value of assessing prednisolone pharmacokinetics before and after renal transplantation

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12 December 2020

Self-catalyzed destruction of cytochrome P-450: covalent binding of ethynyl sterols to prosthetic heme

1 reference

12 December 2020

Pharmacokinetics and protein binding of prednisolone after oral and intravenous administration

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12 December 2020

Pharmacokinetics of intravenous and oral prednisolone

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12 December 2020

Inhibition and induction of microsomal enzymes in rat. A comparative study of four antimycotics: miconazole, econazole, clotrimazole and ketoconazole

1 reference

12 December 2020

Allograft survival in patients receiving anticonvulsant medications

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12 December 2020

Dose dependent pharmacokinetics of prednisolone

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12 December 2020

Impaired liver function in stable renal allograft recipients

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12 December 2020

The determination of essential clearance, volume, and residence time parameters of recirculating metabolic systems: the reversible metabolism of methylprednisolone and methylprednisone in rabbits

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12 December 2020

Pharmacokinetics of prednisolone after high doses of prednisolone hemisuccinate

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12 December 2020

Altered prednisolone kinetics in patients with the nephrotic syndrome

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12 December 2020

The metabolism of 4-14C prednisolone

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12 December 2020

Prednisolone disposition in steroid-dependent asthmatic children.

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12 December 2020

Adverse effect of rifampicin administration on steroid-dependent asthma

1 reference

12 December 2020

Diurnal variation of prednisolone binding to serum corticosteroid-binding globulin in man

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12 December 2020

Kinetics and dynamics of prednisolone

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12 December 2020

Enhancement of the anti-inflammatory action of hydrocortisone by estrogen

1 reference

12 December 2020

Errors in interpretation of data from equilibrium dialysis protein binding experiments

1 reference

12 December 2020

Prednisone and prednisolone bioavailability in renal transplant patients

1 reference

12 December 2020

Prednisone for chronic active hepatitis: pharmacokinetics and serum binding in patients with chronic active hepatitis and steroid major side effects

1 reference

12 December 2020

In vitro effects of fluconazole (UK-49,858) and ketoconazole on mouse lymphocyte proliferation and on Candida blastospore destruction by human polymorphonuclear leukocytes

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12 December 2020

Noncompartmental Determination of the Steady‐State Volume of Distribution

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12 December 2020

Absorption of delayed-release prednisolone in ulcerative colitis and Crohn's disease

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12 December 2020

Tissue distribution of prednisolone in the rabbit

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12 December 2020

Impairment of prednisolone disposition in patients with Graves' disease taking methimazole

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12 December 2020

Prednisolone binding to albumin and transcortin in the presence of cortisol

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12 December 2020

10.2165/00003088-199019020-00003

Identifiers

DOI

1 reference

PubMed ID

2199128

Dimensions Publication ID

25 August 2017

0 references

1 reference

PubMed ID

2199128