(Q37945726)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21999473%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

title

Mode of action of agomelatine: synergy between melatonergic and 5-HT2C receptors (English)

1 reference

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14 February 2020

2

1 reference

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14 February 2020

Raffaella Molteni

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21999473%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Laura Musazzi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21999473%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Francesca Calabrese

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21999473%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Daniela Tardito

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21999473%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

author name string

Giorgio Racagni

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21999473%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Maurizio Popoli

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21999473%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

publication date

14 October 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21999473%20AND%20SRC:MED&resulttype=core&format=json

World Journal of Biological Psychiatry

14 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21999473%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

volume

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21999473%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21999473%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

page(s)

574-587

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21999473%20AND%20SRC:MED&resulttype=core&format=json

Efficacy of melatonin treatment in jet lag, shift work, and blindness.

14 February 2020

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Agomelatine, a new antidepressant, induces regional changes in hippocampal neurogenesis

21 January 2018

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Antidepressant-like effects of agomelatine (S 20098) in the learned helplessness model.

21 January 2018

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The role of CREB in depression and antidepressant treatment

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Chronic antidepressants reduce depolarization-evoked glutamate release and protein interactions favoring formation of SNARE complex in hippocampus.

21 January 2018

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Cell "circadian" cycle: new role for mammalian core clock genes

21 January 2018

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BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis

21 January 2018

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The immediate early gene arc/arg3.1: regulation, mechanisms, and function.

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Neuronal plasticity: a link between stress and mood disorders

21 January 2018

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Modulation of neuroplastic molecules in selected brain regions after chronic administration of the novel antidepressant agomelatine

21 January 2018

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Melatonin and the metabolic syndrome: physiopathologic and therapeutical implications

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21 January 2018

The many faces of CREB

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The regulation of central and peripheral circadian clocks in humans

21 January 2018

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Agomelatine(S 20098) antagonizes the penile erections induced by the stimulation of 5-HT2C receptors in Wistar rats

21 January 2018

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The NGF saga: from animal models of psychosocial stress to stress-related psychopathology

21 January 2018

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Proteomic analysis reveals the role of synaptic vesicle cycling in sustaining the suprachiasmatic circadian clock

21 January 2018

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S32006, a novel 5-HT2C receptor antagonist displaying broad-based antidepressant and anxiolytic properties in rodent models

21 January 2018

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Selective blockade of serotonin-2C/2B receptors enhances mesolimbic and mesostriatal dopaminergic function: a combined in vivo electrophysiological and microdialysis study

21 January 2018

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Central serotonin2C receptor: from physiology to pathology

21 January 2018

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Melatonin for the Treatment of Sleep Disturbances in Major Depressive Disorder

21 January 2018

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Circadian oscillation of hippocampal MAPK activity and cAmp: implications for memory persistence.

21 January 2018

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Melatonin receptors in humans: biological role and clinical relevance

21 January 2018

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Circadian misalignment in major depressive disorder

21 January 2018

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Post-translational modifications regulate the ticking of the circadian clock.

21 January 2018

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Contributions of 5-HT(2C) receptors to multiple actions of central serotonin systems

21 January 2018

1 reference

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Melatonin and its new agonist S-20098 restore synchronized sleep fragmented by experimental trypanosome infection in the rat.

21 January 2018

1 reference

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Challenging the omnipotence of the suprachiasmatic timekeeper: are circadian oscillators present throughout the mammalian brain?

21 January 2018

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Melatonin--a pleiotropic, orchestrating regulator molecule

21 January 2018

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A clockwork web: circadian timing in brain and periphery, in health and disease

21 January 2018

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A phase advance of the light-dark cycle stimulates production of BDNF, but not of other neurotrophins, in the adult rat cerebral cortex: association with the activation of CREB.

21 January 2018

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Efficacy of the novel antidepressant agomelatine on the circadian rest-activity cycle and depressive and anxiety symptoms in patients with major depressive disorder: a randomized, double-blind comparison with sertraline

21 January 2018

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Is there a direct retina-raphe-suprachiasmatic nucleus pathway in the rat?

21 January 2018

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Serotonin, excitatory amino acids and the photic control of melatonin rhythms and SCN c-FOS in the rat.

21 January 2018

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Agomelatine in the treatment of major depressive disorder: potential for clinical effectiveness

21 January 2018

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The circadian system and melatonin: lessons from rats and mice.

21 January 2018

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Sleep disturbances and depression: a challenge for antidepressants

21 January 2018

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Posttranslational mechanisms regulate the mammalian circadian clock

21 January 2018

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Melatonin shifts human circadian rhythms according to a phase-response curve

21 January 2018

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Neuroendocrine profiles in mood disorders

21 January 2018

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Determination of the dose of agomelatine, a melatoninergic agonist and selective 5-HT(2C) antagonist, in the treatment of major depressive disorder: a placebo-controlled dose range study

21 January 2018

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Mammalian circadian biology: elucidating genome-wide levels of temporal organization

21 January 2018

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Circuit projection from suprachiasmatic nucleus to ventral tegmental area: a novel circadian output pathway

21 January 2018

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Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites

21 January 2018

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Melatonin exerts an antidepressant-like effect in the tail suspension test in mice: evidence for involvement of N-methyl-D-aspartate receptors and the L-arginine-nitric oxide pathway.

21 January 2018

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New insights into BDNF function in depression and anxiety

21 January 2018

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Brain clocks: from the suprachiasmatic nuclei to a cerebral network

21 January 2018

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Serotonin 5-HT2C receptors as a target for the treatment of depressive and anxious states: focus on novel therapeutic strategies

21 January 2018

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The Novel Melatonin Agonist Agomelatine (S20098) Is an Antagonist at 5-Hydroxytryptamine2C Receptors, Blockade of Which Enhances the Activity of Frontocortical Dopaminergic and Adrenergic Pathways

21 January 2018

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Anxiolytic properties of agomelatine, an antidepressant with melatoninergic and serotonergic properties: role of 5-HT2C receptor blockade

21 January 2018

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Synergistic mechanisms in the modulation of the neurotrophin BDNF in the rat prefrontal cortex following acute agomelatine administration

21 January 2018

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Immunohistochemical localization of serotonin receptors in the rat suprachiasmatic nucleus

21 January 2018

1 reference

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Acute stress increases depolarization-evoked glutamate release in the rat prefrontal/frontal cortex: the dampening action of antidepressants

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2011.595823

Behavioural and neuroplastic effects of the new-generation antidepressant agomelatine compared to fluoxetine in glucocorticoid receptor-impaired mice

21 January 2018

1 reference

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Interactions of selective serotonin reuptake inhibitors with the serotonin 5-HT2c receptor

21 January 2018

1 reference

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Bidirectional communication between sleep and circadian rhythms and its implications for depression: lessons from agomelatine

21 January 2018

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Effect of agomelatine in the chronic mild stress model of depression in the rat.

21 January 2018

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The pharmacological properties of antidepressants

21 January 2018

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Entrainment of rat circadian rhythms by the melatonin agonist S-20098 requires intact suprachiasmatic nuclei but not the pineal

21 January 2018

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NPAS2: an analog of clock operative in the mammalian forebrain

21 January 2018

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Coordination of circadian timing in mammals

21 January 2018

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Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders

21 January 2018

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Entrainment of free-running circadian rhythms by melatonin in blind people

21 January 2018

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A direct retinal projection to the dorsal raphe nucleus in the rat.

21 January 2018

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Circadian rhythms in depression and recovery: evidence for blunted amplitude as the main chronobiological abnormality

21 January 2018

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Mechanisms contributing to the phase-dependent regulation of neurogenesis by the novel antidepressant, agomelatine, in the adult rat hippocampus.

21 January 2018

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21 January 2018

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The genetics of mammalian circadian order and disorder: implications for physiology and disease

21 January 2018

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Signaling pathways regulating gene expression, neuroplasticity, and neurotrophic mechanisms in the action of antidepressants: a critical overview.

21 January 2018

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Early induction of CREB activation and CREB-regulating signalling by antidepressants.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2011.595823

Blockade of stress-induced increase of glutamate release in the rat prefrontal/frontal cortex by agomelatine involves synergy between melatonergic and 5-HT2C receptor-dependent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2011.595823

Repeated administration of imipramine attenuates glutamatergic transmission in rat frontal cortex

21 January 2018

1 reference

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21 January 2018

1 reference

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Arc/Arg3.1: linking gene expression to synaptic plasticity and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2011.595823

The neurobiology of circadian rhythms.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2011.595823

Comparative effects of a melatonin agonist on the circadian system in mice and Syrian hamsters

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2011.595823

The suprachiasmatic nucleus: a 25-year retrospective

21 January 2018

1 reference

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Melatonin receptor (MT1) knockout mice display depression-like behaviors and deficits in sensorimotor gating.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2011.595823

Biological rhythm disturbances in mood disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2011.595823

GSK-3 beta inhibits presynaptic vesicle exocytosis by phosphorylating P/Q-type calcium channel and interrupting SNARE complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2011.595823

Twenty-four-hour profiles of body temperature and plasma TSH in bipolar patients during depression and during remission and in normal control subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F15622975.2011.595823

10.3109/15622975.2011.595823

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21999473%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference