(Q37946232)

25 August 2017

title

Lgr5 and Lgr6 as markers to study adult stem cell roles in self-renewal and cancer (English)

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25 August 2017

M Leushacke

1

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25 August 2017

N Barker

series ordinal

2

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25 August 2017

language of work or name

English

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publication date

17 October 2011

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25 August 2017

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25 August 2017

volume

31

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25 August 2017

issue

25

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25 August 2017

page(s)

3009-3022

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Tissue-resident adult stem cell populations of rapidly self-renewing organs

25 August 2017

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1 reference

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Crypt stem cells as the cells-of-origin of intestinal cancer

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A genetic model for colorectal tumorigenesis

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Effects of telomerase and telomere length on epidermal stem cell behavior

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The tortoise and the hair: slow-cycling cells in the stem cell race

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More than one way to skin . .

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Male and female Drosophila germline stem cells: two versions of immortality.

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Multiple classes of stem cells in cutaneous epithelium: a lineage analysis of adult mouse skin

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A two-step mechanism for stem cell activation during hair regeneration

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The birth of therapy with cultured cells

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De novo crypt formation and juvenile polyposis on BMP inhibition in mouse intestine

21 January 2018

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The Three Subfamilies of Leucine-Rich Repeat-Containing G Protein-Coupled Receptors (LGR): Identification of LGR6 and LGR7 and the Signaling Mechanism for LGR7

21 January 2018

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Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region

21 January 2018

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Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of beta-catenin

21 January 2018

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Lgr5 marks cycling, yet long-lived, hair follicle stem cells.

21 January 2018

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Lineage commitment and maturation of epithelial cells in the gut.

21 January 2018

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Dynamics of epithelial cells in the corpus of the mouse stomach. I. Identification of proliferative cell types and pinpointing of the stem cell

21 January 2018

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Wounding enhances epidermal tumorigenesis by recruiting hair follicle keratinocytes.

21 January 2018

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R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis

21 January 2018

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Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU.

21 January 2018

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Mitogenic influence of human R-spondin1 on the intestinal epithelium

21 January 2018

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Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

21 January 2018

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Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

21 January 2018

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Coexistence of quiescent and active adult stem cells in mammals

21 January 2018

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Stem cell niche: structure and function

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.479

Gastrointestinal stem cells in self-renewal and cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.479

Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.479

Intestinal stem cell replacement follows a pattern of neutral drift

21 January 2018

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The intestinal epithelial stem cell

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.479

Leucine-rich repeat-containing, G protein-coupled receptor 4 null mice exhibit intrauterine growth retardation associated with embryonic and perinatal lethality

21 January 2018

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The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse

21 January 2018

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Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cells

21 January 2018

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Capturing and profiling adult hair follicle stem cells.

21 January 2018

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Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo

21 January 2018

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A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

21 January 2018

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Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation

21 January 2018

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Canonical Wnt signals are essential for homeostasis of the intestinal epithelium

21 January 2018

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APC mutations occur early during colorectal tumorigenesis

21 January 2018

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Spindle orientation bias in gut epithelial stem cell compartments is lost in precancerous tissue.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.479

Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.479

Identification and expansion of human colon-cancer-initiating cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.479

Stabilization of beta-catenin by genetic defects in melanoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Live and let die in the intestinal epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Signaling pathways in intestinal development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Bmi1 is expressed in vivo in intestinal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Top-down morphogenesis of colorectal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Tracking adult stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Generalized lacZ expression with the ROSA26 Cre reporter strain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Development of gastric tumors in Apc(Min/+) mice by the activation of the beta-catenin/Tcf signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Defining the epithelial stem cell niche in skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Overexpression of leucine-rich repeat-containing G protein-coupled receptor 5 in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Stem cells, self-renewal, and differentiation in the intestinal epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

The Intestinal Wnt/TCF Signature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Transcription factor achaete scute-like 2 controls intestinal stem cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Wnt signalling induces maturation of Paneth cells in intestinal crypts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Expression pattern of the orphan receptor LGR4/GPR48 gene in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Cells of origin in cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.479

Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

LGR5 is a negative regulator of tumourigenicity, antagonizes Wnt signalling and regulates cell adhesion in colorectal cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Induced pluripotent stem cell lines derived from human somatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Stem cells and their implications for colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Distinct self-renewal and differentiation phases in the niche of infrequently dividing hair follicle stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Extreme sensitivity of some intestinal crypt cells to X and gamma irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Tumor growth need not be driven by rare cancer stem cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Identification of genes required for cytoplasmic localization in early C. elegans embryos

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

The constant renewal of the intestinal epithelium in the albino rat

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Morphogenesis and renewal of hair follicles from adult multipotent stem cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Location of stem cells of human hair follicles by clonal analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Significance of Lgr5(+ve) cancer stem cells in the colon and rectum

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

Involvement of follicular stem cells in forming not only the follicle but also the epidermis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.479

31 March 2020

Identifiers

DOI

10.1038/ONC.2011.479

1 reference

Dimensions Publication ID

25 August 2017

1050404980

0 references

1 reference