(Q37950461)

25 August 2017

Strategies for therapy of retinal diseases using systemic drug delivery: relevance of transporters at the blood-retinal barrier (English)

1 reference

25 August 2017

1 reference

Ken-ichi Hosoya

1

1 reference

25 August 2017

Masatoshi Tomi

series ordinal

2

1 reference

25 August 2017

Masanori Tachikawa

series ordinal

3

1 reference

25 August 2017

language of work or name

English

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publication date

29 October 2011

1 reference

Expert Opinion on Drug Delivery

25 August 2017

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25 August 2017

8

1 reference

25 August 2017

1571-1587

1 reference

25 August 2017

12

1 reference

Current and future ophthalmic drug delivery systems. A shift to the posterior segment.

25 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

The cause-specific prevalence of visual impairment in an urban population. The Baltimore Eye Survey

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Delivery of anti-angiogenic molecular therapies for retinal disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Recent progress in ocular drug delivery for posterior segment disease: emphasis on transscleral iontophoresis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Drug delivery to the posterior segment of the eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

The blood-ocular barriers: past, present, and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Inner blood-retinal barrier transporters: role of retinal drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

The role of blood-ocular barrier transporters in retinal drug disposition: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Sodium-coupled monocarboxylate transporters in normal tissues and in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Advances in the cell biology of transport via the inner blood-retinal barrier: establishment of cell lines and transport functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Drug transport in corneal epithelium and blood-retina barrier: emerging role of transporters in ocular pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Involvement of OCTN2 in the transport of acetyl-L-carnitine across the inner blood-retinal barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Comparison of glucose influx and blood flow in retina and brain of diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Cationic amino acid transporter 1-mediated L-arginine transport at the inner blood-retinal barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Ocular pharmacokinetics in rabbits using a novel dual probe microdialysis technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Microdialysis evaluation of the ocular pharmacokinetics of propranolol in the conscious rabbit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Amino acids and their transporters in the retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Carotid artery injection technique: bounds for bolus mixing by plasma and by brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Lipophilicity and transporter influence on blood-retinal barrier permeability: a comparison with blood-brain barrier permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Warfarin sensitivity related to CYP2C9, CYP3A5, ABCB1 (MDR1) and other factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Blood-to-retina transport of biotin via Na+-dependent multivitamin transporter (SMVT) at the inner blood-retinal barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Carrier-mediated transport of amino acids through the blood-retinal and the blood-brain barriers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Vitamin C transport in oxidized form across the rat blood-retinal barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Application of microdialysis to evaluate the efflux transport of estradiol 17-beta glucuronide across the rat blood-retinal barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Roles of inner blood-retinal barrier organic anion transporter 3 in the vitreous/retina-to-blood efflux transport of p-aminohippuric acid, benzylpenicillin, and 6-mercaptopurine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Inner blood-retinal barrier GLUT1 in long-term diabetic rats: an immunogold electron microscopic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Glycopeptide enkephalin analogues produce analgesia in mice: evidence for penetration of the blood-brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Blood-to-retina transport of creatine via creatine transporter (CRT) at the rat inner blood-retinal barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

L-type amino acid transporter 1-mediated L-leucine transport at the inner blood-retinal barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Involvement of LAT1 and LAT2 in the high- and low-affinity transport of L-leucine in human retinal pigment epithelial cells (ARPE-19 cells).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

The 4F2hc/LAT1 complex transports L-DOPA across the blood-brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Identification and functional characterization of a Na(+)-independent large neutral amino acid transporter (LAT2) on ARPE-19 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Effect of L-dopa on visual evoked potential in patients with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Eye-preservation treatment of retinoblastoma with vitreous seeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Conditionally immortalized retinal capillary endothelial cell lines (TR-iBRB) expressing differentiated endothelial cell functions derived from a transgenic rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Evaluation of amino acid-mustard transport as L-type amino acid transporter 1 (LAT1)-mediated alkylating agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1): insights into the mechanisms of substrate recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Prevention of Ornithine Cytotoxicity by Nonpolar Side Chain Amino Acids in Retinal Pigment Epithelial Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Na+- and Cl--coupled active transport of carnitine by the amino acid transporter ATB(0,+) from mouse colon expressed in HRPE cells and Xenopus oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Amino Acid Transporter ATB0,+ as a delivery system for drugs and prodrugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Transport of amino acid-based prodrugs by the Na+- and Cl(-) -coupled amino acid transporter ATB0,+ and expression of the transporter in tissues amenable for drug delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Transport of amino acid esters and the amino-acid-based prodrug valganciclovir by the amino acid transporter ATB(0,+).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Function and regulation of taurine transport at the inner blood-retinal barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Characteristics of glycine transport across the inner blood-retinal barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Activation of carrier-mediated transport of L-cystine at the blood-brain and blood-retinal barriers in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Inner blood-retinal barrier mediates l-isomer-predominant transport of serine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Distribution of monocarboxylate transporters MCT1 and MCT2 in rat retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Lactate transport through the blood-retinal and the blood-brain barrier in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

MCT1-mediated transport of L-lactic acid at the inner blood-retinal barrier: a possible route for delivery of monocarboxylic acid drugs to the retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Overview of the proton-coupled MCT (SLC16A) family of transporters: characterization, function and role in the transport of the drug of abuse gamma-hydroxybutyric acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Molecular features, regulation, and function of monocarboxylate transporters: implications for drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Transport of nicotinate and structurally related compounds by human SMCT1 (SLC5A8) and its relevance to drug transport in the mammalian intestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Transport by SLC5A8 with subsequent inhibition of histone deacetylase 1 (HDAC1) and HDAC3 underlies the antitumor activity of 3-bromopyruvate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Functional and molecular characterization of adenosine transport at the rat inner blood-retinal barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

The equilibrative nucleoside transporter family, SLC29

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Transport of antiviral 3'-deoxy-nucleoside drugs by recombinant human and rat equilibrative, nitrobenzylthioinosine (NBMPR)-insensitive (ENT2) nucleoside transporter proteins produced in Xenopus oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Intrathecal chemotherapy for recurrent central nervous system intraocular lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Management of primary intraocular lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Involvement of reduced folate carrier 1 in the inner blood-retinal barrier transport of methyltetrahydrofolate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Expression and differential polarization of the reduced-folate transporter-1 and the folate receptor alpha in mammalian retinal pigment epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Cloning and functional characterization of the proton-coupled electrogenic folate transporter and analysis of its expression in retinal cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

The safety of intraocular methotrexate in silicone-filled eyes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

The risk of myocardial infarction associated with antihypertensive drug therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Tariquidar-induced P-glycoprotein inhibition at the rat blood-brain barrier studied with (R)-11C-verapamil and PET.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Na(+)-independent choline transport in rat retinal capillary endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Polyspecific organic cation transporters: structure, function, physiological roles, and biopharmaceutical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Characterization of brimonidine transport in retinal pigment epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Distribution of brimonidine into anterior and posterior tissues of monkey, rabbit, and rat eyes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Memantine in dementia: a review of the current evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Topical and systemic drug delivery to the posterior segments

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Use of memantine in progressive glaucoma. Case report

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Ocular penetration of cyclosporine A in the rat eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Ocular penetration of cyclosporin A. III: The human eye

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Efflux protein expression in human retinal pigment epithelium cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Expression of ATP-binding cassette transporters at the inner blood-retinal barrier in a neonatal mouse model of oxygen-induced retinopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Expression of multidrug resistance-associated protein (MRP) in human retinal pigment epithelial cells and its interaction with BAPSG, a novel aldose reductase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

ATP-binding cassette transporter G2 mediates the efflux of phototoxins on the luminal membrane of retinal capillary endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Contribution of organic anion transporter 3 (Slc22a8) to the elimination of p-aminohippuric acid and benzylpenicillin across the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Multichannel liquid chromatography-tandem mass spectrometry cocktail method for comprehensive substrate characterization of multidrug resistance-associated protein 4 transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Application of magnetically isolated rat retinal vascular endothelial cells for the determination of transporter gene expression levels at the inner blood-retinal barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Probenecid treatment enhances retinal and brain delivery of N-4-benzoylaminophenylsulfonylglycine: an anionic aldose reductase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Contribution of carrier-mediated transport systems to the blood-brain barrier as a supporting and protecting interface for the brain; importance for CNS drug discovery and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Carrier-mediated transport of H1-antagonist at the blood-brain barrier: a common transport system of H1-antagonists and lipophilic basic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

Choline transport through the blood-retinal and the blood-brain barrier in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.628983

10.1517/17425247.2011.628983

21 January 2018

Identifiers

DOI

1 reference

25 August 2017

1 reference