(Q37954706)

25 August 2017

title

Absolute quantitation of protein therapeutics in biological matrices by enzymatic digestion and LC-MS. (English)

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25 August 2017

Fumin Li

1

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25 August 2017

Douglas Fast

series ordinal

2

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25 August 2017

Steve Michael

series ordinal

3

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25 August 2017

language of work or name

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1 November 2011

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25 August 2017

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25 August 2017

volume

3

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25 August 2017

issue

21

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25 August 2017

page(s)

2459-2480

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Protein therapeutics: a summary and pharmacological classification

25 August 2017

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Protein quantification by isotope dilution mass spectrometry of proteolytic fragments: cleavage rate and accuracy.

21 January 2018

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Proteolysis in mixed organic-aqueous solvent systems: applications for peptide mass mapping using mass spectrometry

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Efficient and specific trypsin digestion of microgram to nanogram quantities of proteins in organic-aqueous solvent systems

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Comparison of digestion protocols for microgram quantities of enriched protein samples.

21 January 2018

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Quantification of intermediate-abundance proteins in serum by multiple reaction monitoring mass spectrometry in a single-quadrupole ion trap.

21 January 2018

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Quantification of C-reactive protein in the serum of patients with rheumatoid arthritis using multiple reaction monitoring mass spectrometry and 13C-labeled peptide standards

21 January 2018

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Quantitation of a recombinant monoclonal antibody in monkey serum by liquid chromatography-mass spectrometry.

21 January 2018

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Quantification of Alefacept, an immunosuppressive fusion protein in human plasma using a protein analogue internal standard, trypsin cleaved signature peptides and liquid chromatography tandem mass spectrometry

21 January 2018

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21 January 2018

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Comparative evaluation of current peptide production platforms used in absolute quantification in proteomics

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Reversed-phase high-performance liquid chromatographic prefractionation of immunodepleted human serum proteins to enhance mass spectrometry identification of lower-abundant proteins

21 January 2018

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21 January 2018

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Depletion of multiple high-abundance proteins improves protein profiling capacities of human serum and plasma.

21 January 2018

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21 January 2018

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Evaluation of multiprotein immunoaffinity subtraction for plasma proteomics and candidate biomarker discovery using mass spectrometry.

21 January 2018

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Ultra-performance liquid chromatography coupled to time-of-flight mass spectrometry for robust, high-throughput quantitative analysis of an automated metabolic stability assay, with simultaneous determination of metabolic data

21 January 2018

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Quantification and rapid metabolite identification in drug discovery using API time-of-flight LC/MS.

21 January 2018

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Quantitative-qualitative data acquisition using a benchtop Orbitrap mass spectrometer

21 January 2018

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Quantitation of small molecules using high-resolution accurate mass spectrometers - a different approach for analysis of biological samples

21 January 2018

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Advances in bioanalytical LC-MS using the Orbitrap™ mass analyzer

21 January 2018

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https://api.crossref.org/works/10.4155%2FBIO.11.237

Targeted ion parking for the quantitation of biotherapeutic proteins: concepts and preliminary data

21 January 2018

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https://api.crossref.org/works/10.4155%2FBIO.11.237

Application of dried blood spots combined with HPLC-MS/MS for the quantification of acetaminophen in toxicokinetic studies.

21 January 2018

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https://api.crossref.org/works/10.4155%2FBIO.11.237

Use of dried blood spots in drug development: pharmacokinetic considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.11.237

Dried blood spots as a sample collection technique for the determination of pharmacokinetics in clinical studies: considerations for the validation of a quantitative bioanalytical method.

21 January 2018

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https://api.crossref.org/works/10.4155%2FBIO.11.237

Function and regulation of the mammalian copper-transporting ATPases: insights from biochemical and cell biological approaches

21 January 2018

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https://api.crossref.org/works/10.4155%2FBIO.11.237

Fit-for-purpose method development and validation for successful biomarker measurement.

21 January 2018

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https://api.crossref.org/works/10.4155%2FBIO.11.237

Critical comparison of MS and immunoassays for the bioanalysis of therapeutic antibodies

21 January 2018

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https://api.crossref.org/works/10.4155%2FBIO.11.237

Therapeutic monoclonal antibody concentration monitoring: free or total?

21 January 2018

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https://api.crossref.org/works/10.4155%2FBIO.11.237

Serum Concentrations of Free Diphenylhydantoin and their Relationship To Clinical Intoxication

21 January 2018

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https://api.crossref.org/works/10.4155%2FBIO.11.237

Investigation of the immunogenicity of a protein drug using equilibrium dialysis and liquid chromatography tandem mass spectrometry detection.

21 January 2018

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https://api.crossref.org/works/10.4155%2FBIO.11.237

Agreement of rubella IgG antibody measured in serum and dried blood spots using two commercial enzyme-linked immunosorbent assays

21 January 2018

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Retrospective determination of ceruloplasmin in newborn screening blood spots of patients with Wilson disease

21 January 2018

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21 January 2018

Identifiers

DOI

10.4155/BIO.11.237

1 reference

25 August 2017

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