(Q31032140)

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Ultra-performance liquid chromatography coupled to time-of-flight mass spectrometry for robust, high-throughput quantitative analysis of an automated metabolic stability assay, with simultaneous determination of metabolic data

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scholarly article

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Europe PubMed Central

PubMed publication ID

28 June 2017

Ultra-performance liquid chromatography coupled to time-of-flight mass spectrometry for robust, high-throughput quantitative analysis of an automated metabolic stability assay, with simultaneous determination of metabolic data (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 June 2017

1 reference

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Desmond O'Connor

1

1 reference

Europe PubMed Central

PubMed publication ID

28 June 2017

Russell Mortishire-Smith

2

1 reference

Europe PubMed Central

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28 June 2017

Denise Morrison

3

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Europe PubMed Central

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28 June 2017

Amy Davies

4

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Europe PubMed Central

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28 June 2017

Maria Dominguez

5

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28 June 2017

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1 January 2006

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28 June 2017

Rapid Communications in Mass Spectrometry

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Europe PubMed Central

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28 June 2017

20

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28 June 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

28 June 2017

851-857

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Europe PubMed Central

PubMed publication ID

28 June 2017

Prediction of pharmacokinetic properties using experimental approaches during early drug discovery

1 reference

https://api.crossref.org/works/10.1002%2FRCM.2385

21 January 2018

In vitro high throughput screening of compounds for favorable metabolic properties in drug discovery

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Improving the decision-making process in the structural modification of drug candidates: enhancing metabolic stability

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Application of parallel liquid chromatography/mass spectrometry for high throughput microsomal stability screening of compound libraries

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21 January 2018

Automatic mass spectrometry method development for drug discovery: application in metabolic stability assays.

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21 January 2018

Integration of knowledge-based metabolic predictions with liquid chromatography data-dependent tandem mass spectrometry for drug metabolism studies: application to studies on the biotransformation of indinavir

1 reference

https://api.crossref.org/works/10.1002%2FRCM.2385

21 January 2018

A novel approach to perform metabolite screening during the quantitative LC-MS/MS analyses of in vitro metabolic stability samples using a hybrid triple-quadrupole linear ion trap mass spectrometer

1 reference

https://api.crossref.org/works/10.1002%2FRCM.2385

21 January 2018

Quantification and rapid metabolite identification in drug discovery using API time-of-flight LC/MS.

1 reference

https://api.crossref.org/works/10.1002%2FRCM.2385

21 January 2018

Increasing throughput and information content for in vitro drug metabolism experiments using ultra-performance liquid chromatography coupled to a quadrupole time-of-flight mass spectrometer

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21 January 2018

Investigating the human metabolism of acetaminophen using UPLC and exact mass oa-TOF MS.

1 reference

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21 January 2018

Use of a five-channel multiplexed electrospray quadrupole time-of-flight hybrid mass spectrometer for metabolite identification

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21 January 2018

Accelerated throughput metabolic route screening in early drug discovery using high-resolution liquid chromatography/quadrupole time-of-flight mass spectrometry and automated data analysis

1 reference

https://api.crossref.org/works/10.1002%2FRCM.2385

21 January 2018

Atmospheric pressure ionization time-of-flight mass spectrometry coupled with fast liquid chromatography for quantitation and accurate mass measurement of five pharmaceutical drugs in human plasma

1 reference

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21 January 2018

Quadrupole time‐of‐flight versus triple‐quadrupole mass spectrometry for the determination of non‐steroidal antiinflammatory drugs in surface water by liquid chromatography/tandem mass spectrometry

1 reference

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21 January 2018

Quantitation and accurate mass analysis of pesticides in vegetables by LC/TOF-MS.

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21 January 2018

Optimizing an ultrafast generic high-performance liquid chromatography/tandem mass spectrometry method for faster discovery pharmacokinetic sample throughput.

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Fast LC/MS in the analysis of small molecules

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Comparison of ultra-performance liquid chromatography and high-performance liquid chromatography for the determination of priority pesticides in baby foods by tandem quadrupole mass spectrometry

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21 January 2018

Improving LC–MS sensitivity through increases in chromatographic performance: Comparisons of UPLC–ES/MS/MS to HPLC–ES/MS/MS

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21 January 2018

Ultra-performance liquid chromatography coupled to quadrupole-orthogonal time-of-flight mass spectrometry

1 reference

https://api.crossref.org/works/10.1002%2FRCM.2385

21 January 2018

Monooxygenase activity of human liver in microsomal fractions of needle biopsy specimens

1 reference

https://api.crossref.org/works/10.1002%2FRCM.2385

21 January 2018

'All-in-one' analysis for metabolite identification using liquid chromatography/hybrid quadrupole time-of-flight mass spectrometry with collision energy switching

1 reference

https://api.crossref.org/works/10.1002%2FRCM.2385

21 January 2018

Experimental Design on Single-Time-Point High-Throughput Microsomal Stability Assay

1 reference

https://api.crossref.org/works/10.1002%2FRCM.2385

21 January 2018

Identifiers

10.1002/RCM.2385

1 reference

Europe PubMed Central

PubMed publication ID

28 June 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 June 2017

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