(Q37957618)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094586%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

NKL homeobox genes in leukemia (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094586%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094586%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

author name string

I Homminga

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094586%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

R Pieters

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094586%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

publication date

18 November 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094586%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094586%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094586%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094586%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

page(s)

572-581

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094586%20AND%20SRC:MED&resulttype=core&format=json

The molecular organization of the Antennapedia locus of Drosophila

16 January 2020

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Detection of differential mitotic cell age in bone marrow CD34(+) cells from patients with myelodysplastic syndrome and acute leukemia by analysis of an epigenetic molecular clock DNA signature.

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21 January 2018

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Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia.

21 January 2018

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Densely interconnected transcriptional circuits control cell states in human hematopoiesis

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Prognostic significance of molecular-cytogenetic abnormalities in pediatric T-ALL is not explained by immunophenotypic differences.

21 January 2018

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Prognostic importance of TLX1 (HOX11) oncogene expression in adults with T-cell acute lymphoblastic leukaemia.

21 January 2018

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Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

21 January 2018

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Expression of HOX11 in childhood T-lineage acute lymphoblastic leukaemia can occur in the absence of cytogenetic aberration at 10q24: a study from the Children's Cancer Group (CCG)

21 January 2018

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t(5;14)/HOX11L2-positive T-cell acute lymphoblastic leukemia. A collaborative study of the Groupe Français de Cytogénétique Hématologique (GFCH).

21 January 2018

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Clinical significance of HOX11L2 expression linked to t(5;14)(q35;q32), of HOX11 expression, and of SIL-TAL fusion in childhood T-cell malignancies: results of EORTC studies 58881 and 58951

21 January 2018

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Two forms of Hox11 a T cell leukemia oncogene, are expressed in fetal spleen but not in primary lymphocytes.

21 January 2018

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Hox11 acts cell autonomously in spleen development and its absence results in altered cell fate of mesenchymal spleen precursors

21 January 2018

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Tlx3 and Tlx1 are post-mitotic selector genes determining glutamatergic over GABAergic cell fates

21 January 2018

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The evolution of homeobox genes: Implications for the study of brain development

21 January 2018

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A model for spontaneous B-lineage lymphomas in IgHmu-HOX11 transgenic mice.

21 January 2018

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The TLX1 oncogene drives aneuploidy in T cell transformation

21 January 2018

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Enforced expression of HOX11 is associated with an immature phenotype in J2E erythroid cells

21 January 2018

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Role of TLX1 in T-cell acute lymphoblastic leukaemia pathogenesis

21 January 2018

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TLX1/HOX11-induced hematopoietic differentiation blockade

21 January 2018

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TLX1/HOX11 transcription factor inhibits differentiation and promotes a non-haemopoietic phenotype in murine bone marrow cells

21 January 2018

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TLX1/HOX11-mediated disruption of primary thymocyte differentiation prior to the CD4+CD8+ double-positive stage

21 January 2018

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HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint

21 January 2018

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TLX1 and NOTCH coregulate transcription in T cell acute lymphoblastic leukemia cells

21 January 2018

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G1/S transcriptional networks modulated by the HOX11/TLX1 oncogene of T-cell acute lymphoblastic leukemia

21 January 2018

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The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia

21 January 2018

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A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia.

21 January 2018

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21 January 2018

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HOX11L2 expression defines a clinical subtype of pediatric T-ALL associated with poor prognosis.

21 January 2018

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Various types of rearrangements target TLX3 locus in T-cell acute lymphoblastic leukemia

21 January 2018

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Disruption of the RanBP17/Hox11L2 region by recombination with the TCRdelta locus in acute lymphoblastic leukemias with t(5;14)(q34;q11).

21 January 2018

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Cooperative genetic defects in TLX3 rearranged pediatric T-ALL.

21 January 2018

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HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL).

21 January 2018

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Thymic adult T-cell acute lymphoblastic leukemia stratified in standard- and high-risk group by aberrant HOX11L2 expression: experience of the German multicenter ALL study group.

21 January 2018

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NK-like homeodomain proteins activate NOTCH3-signaling in leukemic T-cells

21 January 2018

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Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice

21 January 2018

1 reference

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Activation of miR-17-92 by NK-like homeodomain proteins suppresses apoptosis via reduction of E2F1 in T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

MEF2C is activated by multiple mechanisms in a subset of T-acute lymphoblastic leukemia cell lines

21 January 2018

1 reference

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Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia

21 January 2018

1 reference

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The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

The homeobox gene Hex induces T-cell-derived lymphomas when overexpressed in hematopoietic precursor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Down-regulation of the myeloid homeobox protein Hex is essential for normal T-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Leukemogenic mechanisms and targets of a NUP98/HHEX fusion in acute myeloid leukemia

21 January 2018

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The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9

21 January 2018

1 reference

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Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.330

Fusion of the NUP98 gene and the homeobox gene HOXC13 in acute myeloid leukemia with t(11;12)(p15;q13).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Dissection of the transformation of primary human hematopoietic cells by the oncogene NUP98-HOXA9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Molecular genetics of acute lymphoblastic leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.330

Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.330

Full-length cDNA sequence and genomic organization of human NKX3A - alternative forms and regulation by both androgens and estrogens

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2011.330

The vent-like homeobox gene VENTX promotes human myeloid differentiation and is highly expressed in acute myeloid leukemia

21 January 2018

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VentX, a novel lymphoid-enhancing factor/T-cell factor-associated transcription repressor, is a putative tumor suppressor.

21 January 2018

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VentX trans-activates p53 and p16ink4a to regulate cellular senescence

21 January 2018

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DLX genes as targets of ALL-1: DLX 2,3,4 down-regulation in t(4;11) acute lymphoblastic leukemias

21 January 2018

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Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options

21 January 2018

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Deregulated homeobox gene expression in cancer: cause or consequence?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

The T-cell oncogenic protein HOX11 activates Aldh1 expression in NIH 3T3 cells but represses its expression in mouse spleen development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

The PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

A functional interaction between the histone deacetylase Rpd3 and the corepressor groucho in Drosophila development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

The homeodomain protein NK-3 recruits Groucho and a histone deacetylase complex to repress transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

The proline-rich homeodomain protein recruits members of the Groucho/Transducin-like enhancer of split protein family to co-repress transcription in hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Transcriptional regulation of FHL1 by TLX1/HOX11 is dosage, cell-type and promoter context-dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Transcriptional activation by TLX1/HOX11 involves Gro/TLE corepressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Epigenetic inactivation of the Groucho homologue gene TLE1 in hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

GATA-6 and thyroid transcription factor-1 directly interact and regulate surfactant protein-C gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

A triad of serum response factor and the GATA and NK families governs the transcription of smooth and cardiac muscle genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

GATA-4 and Nkx-2.5 coactivate Nkx-2 DNA binding targets: role for regulating early cardiac gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Combinatorial expression of GATA4, Nkx2-5, and serum response factor directs early cardiac gene activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Characterization of the homeodomain gene EMX2: sequence conservation, expression analysis, and a search for mutations in endometrial cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Amplification of the BP1 homeobox gene in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

The c.469+46_56del mutation in the homeobox MSX1 gene--a novel risk factor in breast cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

BARX2 and estrogen receptor-alpha (ESR1) coordinately regulate the production of alternatively spliced ESR1 isoforms and control breast cancer cell growth and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

BP1, a homeoprotein, is significantly expressed in prostate adenocarcinoma and is concordant with prostatic intraepithelial neoplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Prognostic significance of BP1 mRNA expression level in patients with non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Overexpression of BP1, a homeobox gene, is associated with resistance to all-trans retinoic acid in acute promyelocytic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

BP1, a new homeobox gene, is frequently expressed in acute leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Correlation of expression of BP1, a homeobox gene, with estrogen receptor status in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Upregulation of DLX5 promotes ovarian cancer cell proliferation by enhancing IRS-2-AKT signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Activation of placenta-specific transcription factor distal-less homeobox 5 predicts clinical outcome in primary lung cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

A developmentally regulated inducer of EMT, LBX1, contributes to breast cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Expression of MSX2 predicts malignancy of branch duct intraductal papillary mucinous neoplasm of the pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Evaluation of MSX2 mRNA in brush cytology specimens distinguished pancreatic carcinoma from chronic pancreatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Up-regulation of MSX2 enhances the malignant phenotype and is associated with twist 1 expression in human pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Establishment and characterization of an ovarian yolk sac tumor cell line reveals possible involvement of Nkx2.5 in tumor development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Expression of NKX3.1 in normal and malignant tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Silencing of Peroxiredoxin 2 and aberrant methylation of 33 CpG islands in putative promoter regions in human malignant melanomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

MIRA-assisted microarray analysis, a new technology for the determination of DNA methylation patterns, identifies frequent methylation of homeodomain-containing genes in lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

EMX2 is epigenetically silenced and suppresses growth in human lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

CpG island methylation profiling in human salivary gland adenoid cystic carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Epigenetic analysis of childhood acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Genome-wide identification of aberrantly methylated promoter associated CpG islands in acute lymphocytic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

DNA methylation patterns in luminal breast cancers differ from non-luminal subtypes and can identify relapse risk independent of other clinical variables

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

CpG island methylation profiling in human melanoma cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Deletion, methylation, and expression of the NKX3.1 suppressor gene in primary human prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Identification of novel DNA methylation markers in cervical cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Quantitative DNA methylation analysis detects cervical intraepithelial neoplasms type 3 and worse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Large-scale CpG methylation analysis identifies novel candidate genes and reveals methylation hotspots in acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Differential DNA methylation patterns of small B-cell lymphoma subclasses with different clinical behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

CpG island hypermethylation in human astrocytomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

"Promoter array" studies identify cohorts of genes directly regulated by methylation, copy number change, or transcription factor binding in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Transcriptional activation of the cardiac homeobox gene CSX1/NKX2-5 in a B-cell chronic lymphoproliferative disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

Genomic and cDNA clones of the homeotic locus Antennapedia in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

7 January 2021

Incidence and prognostic significance of immunophenotypic subgroups in childhood acute lymphoblastic leukemia: experience of the BFM study 86

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

7 January 2021

Significance of commonly used prognostic factors differs for children with T cell acute lymphocytic leukemia (ALL), as compared to those with B-precursor ALL. A Pediatric Oncology Group (POG) study

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

7 January 2021

Expression of nuclear Notch3 in pancreatic adenocarcinomas is associated with adverse clinical features, and correlates with the expression of STAT3 and phosphorylated Akt

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

7 January 2021

SCL and LMO1 alter thymocyte differentiation: inhibition of E2A-HEB function and pre-T alpha chain expression

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

7 January 2021

Polymorphisms in human homeobox HLX1 and DNA repair RAD51 genes increase the risk of therapy-related acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

7 January 2021

Germ-line mutation of NKX3.1 cosegregates with hereditary prostate cancer and alters the homeodomain structure and function

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

7 January 2021

Differentiation of tumours of ductal and lobular origin: I. Proteomics of invasive ductal and lobular breast carcinomas.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

7 January 2021

Identification of 20 genes aberrantly methylated in human breast cancers

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.330

7 January 2021

Identifiers

DOI

10.1038/LEU.2011.330

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094586%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference