(Q37962018)

26 August 2017

title

Arginine/lysine-methyl/methyl switches: biochemical role of histone arginine methylation in transcriptional regulation (English)

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26 August 2017

Valentina Migliori

1

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26 August 2017

Sameer Phalke

series ordinal

2

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26 August 2017

Marco Bezzi

series ordinal

3

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26 August 2017

Ernesto Guccione

series ordinal

4

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26 August 2017

publication date

1 February 2010

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26 August 2017

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26 August 2017

volume

2

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26 August 2017

issue

1

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26 August 2017

page(s)

119-137

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High-resolution profiling of histone methylations in the human genome

26 August 2017

cites work

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Chromatin modifications and their function

21 January 2018

1 reference

Genomic maps and comparative analysis of histone modifications in human and mouse

21 January 2018

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Myc-binding-site recognition in the human genome is determined by chromatin context

21 January 2018

1 reference

Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome.

21 January 2018

1 reference

Active chromatin domains are defined by acetylation islands revealed by genome-wide mapping

21 January 2018

1 reference

Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter

21 January 2018

1 reference

Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter

21 January 2018

1 reference

The language of covalent histone modifications

21 January 2018

1 reference

Bromodomain: an acetyl-lysine binding domain

21 January 2018

1 reference

The Tudor domain 'Royal Family': Tudor, plant Agenet, Chromo, PWWP and MBT domains

21 January 2018

1 reference

Translating the Histone Code

21 January 2018

1 reference

Signaling network model of chromatin

21 January 2018

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PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing.

21 January 2018

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The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modules

21 January 2018

1 reference

SMN, the product of the spinal muscular atrophy gene, binds preferentially to dimethylarginine-containing protein targets

21 January 2018

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Tudor domains bind symmetrical dimethylated arginines

21 January 2018

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Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

21 January 2018

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High-resolution X-ray and NMR structures of the SMN Tudor domain: conformational variation in the binding site for symmetrically dimethylated arginine residues

21 January 2018

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Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage

21 January 2018

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Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

21 January 2018

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SMN tudor domain structure and its interaction with the Sm proteins

21 January 2018

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Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A

21 January 2018

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The role of Tudor domains in germline development and polar granule architecture

21 January 2018

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Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease

21 January 2018

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Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor

21 January 2018

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The arginine methyltransferase CARM1 regulates the coupling of transcription and mRNA processing.

21 January 2018

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The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2

21 January 2018

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RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination

21 January 2018

1 reference

Nutrient regulates Tor1 nuclear localization and association with rDNA promoter.

21 January 2018

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Structural insight into the recognition of the H3K4me3 mark by the TFIID subunit TAF3.

21 January 2018

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Structure of the HP1 chromodomain bound to histone H3 methylated at lysine 9

21 January 2018

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Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail

21 January 2018

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Double chromodomains cooperate to recognize the methylated histone H3 tail

21 January 2018

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Molecular recognition of histone H3 by the WD40 protein WDR5.

21 January 2018

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Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive

21 January 2018

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Arginine methylation inhibits the binding of proline-rich ligands to Src homology 3, but not WW, domains

21 January 2018

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Regulation of coactivator complex assembly and function by protein arginine methylation and demethylimination

21 January 2018

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Binary switches and modification cassettes in histone biology and beyond.

21 January 2018

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Protein arginine methylation in mammals: who, what, and why

21 January 2018

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Amino acid-base interactions: a three-dimensional analysis of protein-DNA interactions at an atomic level

21 January 2018

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Identification and characterization of the methyl arginines in the fragile X mental retardation protein Fmrp

21 January 2018

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Protein arginine methyltransferases: from unicellular eukaryotes to humans

21 January 2018

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Protein arginine methyltransferases: evolution and assessment of their pharmacological and therapeutic potential

21 January 2018

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Structural and sequence motifs of protein (histone) methylation enzymes

21 January 2018

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FBXO11/PRMT9, a new protein arginine methyltransferase, symmetrically dimethylates arginine residues

21 January 2018

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DRE-1: an evolutionarily conserved F box protein that regulates C. elegans developmental age.

21 January 2018

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Kinetic analysis of human protein arginine N-methyltransferase 2: formation of monomethyl- and asymmetric dimethyl-arginine residues on histone H4

21 January 2018

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Methylation of histone H4 at arginine 3 occurs in vivo and is mediated by the nuclear receptor coactivator PRMT1

21 January 2018

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Methylation of histone H4 by arginine methyltransferase PRMT1 is essential in vivo for many subsequent histone modifications

21 January 2018

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Structure and function of a human TAFII250 double bromodomain module

21 January 2018

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ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation

21 January 2018

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Protein arginine-methyltransferase-dependent oncogenesis

21 January 2018

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mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad

21 January 2018

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Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes

21 January 2018

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Arginine methylation of the histone H3 tail impedes effector binding

21 January 2018

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Global histone modifications in breast cancer correlate with tumor phenotypes, prognostic factors, and patient outcome.

21 January 2018

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Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

21 January 2018

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Methylation of histone H3 by coactivator-associated arginine methyltransferase 1

21 January 2018

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Methylation at arginine 17 of histone H3 is linked to gene activation

21 January 2018

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Hormone-dependent, CARM1-directed, arginine-specific methylation of histone H3 on a steroid-regulated promoter

21 January 2018

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Crosstalk between CARM1 methylation and CBP acetylation on histone H3.

21 January 2018

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Histone arginine methylation regulates pluripotency in the early mouse embryo

21 January 2018

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CARM1 is required in embryonic stem cells to maintain pluripotency and resist differentiation.

21 January 2018

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A methylation-mediator complex in hormone signaling

21 January 2018

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Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300

21 January 2018

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Mouse polycomb proteins bind differentially to methylated histone H3 and RNA and are enriched in facultative heterochromatin

21 January 2018

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A model for transmission of the H3K27me3 epigenetic mark

21 January 2018

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PRMT5 (Janus Kinase-binding Protein 1) Catalyzes the Formation of Symmetric Dimethylarginine Residues in Proteins

21 January 2018

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PRMT7 is a member of the protein arginine methyltransferase family with a distinct substrate specificity

21 January 2018

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The testis-specific factor CTCFL cooperates with the protein methyltransferase PRMT7 in H19 imprinting control region methylation

21 January 2018

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Negative regulation of transcription by the type II arginine methyltransferase PRMT5

21 January 2018

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Expression of BLIMP1/PRMT5 and concurrent histone H2A/H4 arginine 3 dimethylation in fetal germ cells, CIS/IGCNU and germ cell tumors

21 January 2018

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Low levels of miR-92b/96 induce PRMT5 translation and H3R8/H4R3 methylation in mantle cell lymphoma

21 January 2018

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Multivalent engagement of chromatin modifications by linked binding modules

21 January 2018

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DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

21 January 2018

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Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells.

21 January 2018

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The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5

21 January 2018

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Protein lysine methyltransferase G9a acts on non-histone targets

21 January 2018

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G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis

21 January 2018

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The protein arginine methyltransferase Prmt5 is required for myogenesis because it facilitates ATP-dependent chromatin remodeling

21 January 2018

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Arginine methylation at histone H3R2 controls deposition of H3K4 trimethylation

21 January 2018

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PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation

21 January 2018

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Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression

21 January 2018

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Activation of androgen receptor by histone demethylases JMJD2A and JMJD2D.

21 January 2018

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Dynamic regulation of nucleosome positioning in the human genome

21 January 2018

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Histone chaperones in nucleosome eviction and histone exchange

21 January 2018

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Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation

21 January 2018

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Histone H3 tail clipping regulates gene expression

21 January 2018

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Human PAD4 regulates histone arginine methylation levels via demethylimination

21 January 2018

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Histone deimination antagonizes arginine methylation

21 January 2018

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Histone H4-K16 acetylation controls chromatin structure and protein interactions

21 January 2018

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Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation.

21 January 2018

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Functional connection between deimination and deacetylation of histones

21 January 2018

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Methylation of arginine residues interferes with citrullination by peptidylarginine deiminases in vitro.

21 January 2018

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Methylation of the guanidino group of arginine residues prevents citrullination by peptidylarginine deiminase IV.

21 January 2018

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JMJD6 is a histone arginine demethylase

21 January 2018

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Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing

21 January 2018

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Integration of external signaling pathways with the core transcriptional network in embryonic stem cells

21 January 2018

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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

21 January 2018

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Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation

21 January 2018

1 reference

Human protein arginine methyltransferases in vivo--distinct properties of eight canonical members of the PRMT family

21 January 2018

1 reference

Small molecule regulators of protein arginine methyltransferases

21 January 2018

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Synthesis and biological validation of novel synthetic histone/protein methyltransferase inhibitors

21 January 2018

1 reference

Small molecule inhibitors of histone arginine methyltransferases: homology modeling, molecular docking, binding mode analysis, and biological evaluations

21 January 2018

1 reference

A novel arginine methyltransferase inhibitor with cellular activity

21 January 2018

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Virtual screening and biological characterization of novel histone arginine methyltransferase PRMT1 inhibitors

21 January 2018

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Comprehensive analysis of CpG islands in human chromosomes 21 and 22

21 January 2018

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A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters

21 January 2018

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Worms gang up on bacteria

21 January 2018

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Structure and function of eukaryotic DNA methyltransferases

21 January 2018

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The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites

21 January 2018

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A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei

21 January 2018

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Linking DNA methylation and histone modification: patterns and paradigms

21 January 2018

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Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2

21 January 2018

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Human DNMT2 methylates tRNA(Asp) molecules using a DNA methyltransferase-like catalytic mechanism

21 January 2018

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Retrotransposon silencing and telomere integrity in somatic cells of Drosophila depends on the cytosine-5 methyltransferase DNMT2.

21 January 2018

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The methyl-CpG binding domain and the evolving role of DNA methylation in animals

21 January 2018

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Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing

21 January 2018

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A family of human zinc finger proteins that bind methylated DNA and repress transcription

21 January 2018

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The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor

21 January 2018

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N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso

21 January 2018

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UHRF1 plays a role in maintaining DNA methylation in mammalian cells

21 January 2018

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G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis.

21 January 2018

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De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes

21 January 2018

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Epigenome microarray platform for proteome-wide dissection of chromatin-signaling networks

21 January 2018

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A protein-domain microarray identifies novel protein-protein interactions

21 January 2018

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Self-assembling protein microarrays

21 January 2018

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Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/EPI.09.39

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26 August 2017

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