(Q37965128)

26 August 2017

title

Hedgehog signalling in gut development, physiology and cancer (English)

1 reference

26 August 2017

0 references

Juanita L Merchant

1

1 reference

26 August 2017

language of work or name

English

0 references

publication date

5 December 2011

1 reference

26 August 2017

published in

Journal of Physiology

1 reference

26 August 2017

volume

590

1 reference

26 August 2017

issue

3

1 reference

26 August 2017

page(s)

421-432

1 reference

An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasis

26 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Hedgehog signaling is involved in differentiation of normal colonic tissue rather than in tumor proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Processing-dependent trafficking of Sonic hedgehog to the regulated secretory pathway in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Identification of conserved regions and residues within Hedgehog acyltransferase critical for palmitoylation of Sonic Hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Proteolytic processing yields two secreted forms of sonic hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Dispatched mediates Hedgehog basolateral release to form the long-range morphogenetic gradient in the Drosophila wing disk epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Characterization of two patched receptors for the vertebrate hedgehog protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Mouse Dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Activation of Erk by sonic hedgehog independent of canonical hedgehog signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Processing and turnover of the Hedgehog protein in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Cloning of the human GLI2 Promoter: transcriptional activation by transforming growth factor-beta via SMAD3/beta-catenin cooperation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Heparan sulfate-modulated, metalloprotease-mediated sonic hedgehog release from producing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Intracellular Calcium Release and Protein Kinase C Activation Stimulate Sonic Hedgehog Gene Expression During Gastric Acid Secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Requirement of TGFbeta signaling for SMO-mediated carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Primers on molecular pathways GLI: more than just Hedgehog?

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Hedgehog signal activation in gastric pit cell and in diffuse-type gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Sonic Hedgehog as a mediator of long-range signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

The world according to hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Gli proteins in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

21 January 2018

Lysosomes in apoptosis

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Pepsinogens, progastricsins, and prochymosins: structure, function, evolution, and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Identifying and counting epithelial cell types in the "corpus" of the mouse stomach

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

The GLI gene encodes a nuclear protein which binds specific sequences in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Non-canonical activation of GLI transcription factors: implications for targeted anti-cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Autoproteolysis in hedgehog protein biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Sonic hedgehog is essential to foregut development

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Epithelial hedgehog signals pattern the intestinal crypt-villus axis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Mechanisms of Hedgehog signalling in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Gli1 regulates the proliferation and differentiation of HSCs and myeloid progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Hedgehog signaling in gastric physiology and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Not lost in space: trafficking in the hedgehog signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Mature chief cells are cryptic progenitors for metaplasia in the stomach

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

A molecular signature of gastric metaplasia arising in response to acute parietal cell loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Mutations affecting segment number and polarity in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Sonic hedgehog shedding results in functional activation of the solubilized protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Hedgehog signaling in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

The adventures of sonic hedgehog in development and repair. II. Sonic hedgehog and liver development, inflammation, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Expression of Sonic hedgehog pathway genes is altered in colonic neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Comparative biological responses to human Sonic, Indian, and Desert hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

The vertebrate primary cilium is a sensory organelle

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Assembly of primary cilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Identification of a palmitic acid-modified form of human Sonic hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

The product of hedgehog autoproteolytic cleavage active in local and long-range signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Cholesterol modification of hedgehog signaling proteins in animal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

The maturation of mucus-secreting gastric epithelial progenitors into digestive-enzyme secreting zymogenic cells requires Mist1

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

The epigenetic regulation of stem cell factors in hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Morphogen gradients: from generation to interpretation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Nobel prizes: fly development work bears prize-winning fruit

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Hedgehog signaling and gastrointestinal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Mechanisms of Hedgehog pathway activation in cancer and implications for therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Regulation of Gli1 localization by the cAMP/protein kinase A signaling axis through a site near the nuclear localization signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

The evolution of the hedgehog gene family in chordates: insights from amphioxus hedgehog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Astroglial cells in the external granular layer are precursors of cerebellar granule neurons in neonates

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Regulation and function of the sonic hedgehog signal transduction pathway in isolated gastric parietal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Hedgehog-mediated epithelial-to-mesenchymal transition and fibrogenic repair in nonalcoholic fatty liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Post-translational processing and renal expression of mouse Indian hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Hedgehog signaling in development and homeostasis of the gastrointestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Depletion of the colonic epithelial precursor cell compartment upon conditional activation of the hedgehog pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Hedgehog pathway activity is required for the lethality and intestinal phenotypes of mice with hyperactive Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Interleukin-1beta promotes gastric atrophy through suppression of Sonic Hedgehog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

How does cholesterol affect the way Hedgehog works?

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Non-consensus GLI binding sites in Hedgehog target gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

The primary cilium at the crossroads of mammalian hedgehog signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Loss of parietal cell expression of Sonic hedgehog induces hypergastrinemia and hyperproliferation of surface mucous cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Sonic hedgehog relates to colorectal carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Hedgehog is an anti-inflammatory epithelial signal for the intestinal lamina propria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Hedgehog signaling controls homeostasis of adult intestinal smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Reduced pepsin A processing of sonic hedgehog in parietal cells precedes gastric atrophy and transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

The Human Glioma-Associated Oncogene Homolog 1 (GLI1) Family of Transcription Factors in Gene Regulation and Diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.220681

Hedgehog beyond medulloblastoma and basal cell carcinoma

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379690

Comparative genomics on Sonic hedgehog orthologs.

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379690

Hedgehog signals regulate multiple aspects of gastrointestinal development

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379690

Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling

16 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379690

10.1113/JPHYSIOL.2011.220681

16 September 2018

Identifiers

DOI

1 reference

release_2ucarmb32vbabdsw6ahkk72t6i

26 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2ucarmb32vbabdsw6ahkk72t6i

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

3379690

0 references

1 reference