(Q34194163)

31 July 2017

title

Dispatched mediates Hedgehog basolateral release to form the long-range morphogenetic gradient in the Drosophila wing disk epithelium (English)

1 reference

31 July 2017

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7

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31 July 2017

Nicole Gorfinkiel

4

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author name string

Ainhoa Callejo

1

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31 July 2017

Aphrodite Bilioni

2

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31 July 2017

Emanuela Mollica

3

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31 July 2017

Germán Andrés

5

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31 July 2017

Carmen Ibáñez

6

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31 July 2017

Laura Doglio

8

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31 July 2017

Javier Sierra

9

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31 July 2017

Isabel Guerrero

10

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31 July 2017

language of work or name

English

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publication date

20 June 2011

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Proceedings of the National Academy of Sciences of the United States of America

31 July 2017

published in

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31 July 2017

volume

108

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31 July 2017

issue

31

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31 July 2017

page(s)

12591-12598

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Dynamic filopodia transmit intermittent Delta-Notch signaling to drive pattern refinement during lateral inhibition

31 July 2017

cites work

1 reference

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The cell-surface proteins Dally-like and Ihog differentially regulate Hedgehog signaling strength and range during development

5 July 2018

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Genetic and biochemical definition of the Hedgehog receptor

5 July 2018

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Evidence for a role of vertebrate Disp1 in long-range Shh signaling

5 July 2018

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Cellular trafficking of the glypican Dally-like is required for full-strength Hedgehog signaling and wingless transcytosis

5 July 2018

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Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning

5 July 2018

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5 July 2018

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Understanding morphogen gradients: a problem of dispersion and containment

5 July 2018

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5 July 2018

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HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity

5 July 2018

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Rab8-dependent recycling promotes endosomal cholesterol removal in normal and sphingolipidosis cells

5 July 2018

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Orchestrating ontogenesis: variations on a theme by sonic hedgehog

5 July 2018

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Molecular pathways regulating pro-migratory effects of Hedgehog signaling

5 July 2018

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Ventral neural progenitors switch toward an oligodendroglial fate in response to increased Sonic hedgehog (Shh) activity: involvement of Sulfatase 1 in modulating Shh signaling in the ventral spinal cord.

5 July 2018

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Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand

5 July 2018

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Functions of heparan sulfate proteoglycans in cell signaling during development

5 July 2018

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The Hedgehog response network: sensors, switches, and routers

5 July 2018

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Novel lipid modifications of secreted protein signals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

The cholesterol membrane anchor of the Hedgehog protein confers stable membrane association to lipid-modified proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

The subapical compartment: a traffic center in membrane polarity development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

Patched controls the Hedgehog gradient by endocytosis in a dynamin-dependent manner, but this internalization does not play a major role in signal transduction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

Hedgehog signalling in cancer formation and maintenance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

The RND permease superfamily: an ancient, ubiquitous and diverse family that includes human disease and development proteins.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

The notch signalling regulator fringe acts in the Golgi apparatus and requires the glycosyltransferase signature motif DXD.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

beta 2-adrenergic receptor internalization, endosomal sorting, and plasma membrane recycling are regulated by rab GTPases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

The COE transcription factor Collier is a mediator of short-range Hedgehog-induced patterning of the Drosophila wing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

Is dynamin a regular motor or a master regulator?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

Cytonemes: cellular processes that project to the principal signaling center in Drosophila imaginal discs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

The monomeric guanosine triphosphatase rab4 controls an essential step on the pathway of receptor-mediated antigen processing in B cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

Notch signalling mediates segmentation of the Drosophila leg.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

Dual roles for patched in sequestering and transducing Hedgehog

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

The basic-helix-loop-helix domain of Drosophila lethal of scute protein is sufficient for proneural function and activates neurogenic genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

Developmental compartmentalisation of the wing disk of Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

Lakes Beneath the Antarctic Ice Sheet

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1106881108

Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1106881108

Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1106881108

Hedgehog lipid modifications are required for Hedgehog stabilization in the extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1106881108

Lipoprotein-heparan sulfate interactions in the Hh pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1106881108

The glypican Dally-like is required for Hedgehog signalling in the embryonic epidermis of Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1106881108

Reading the Hedgehog morphogen gradient by measuring the ratio of bound to unbound Patched protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1106881108

The ihog cell-surface proteins bind Hedgehog and mediate pathway activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1106881108

Cholesterol modification is necessary for controlled planar long-range activity of Hedgehog in Drosophila epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1106881108

The long-range activity of Hedgehog is regulated in the apical extracellular space by the glypican Dally and the hydrolase Notum

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1106881108

A role for the deep orange and carnation eye color genes in lysosomal delivery in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1106881108

Sightless has homology to transmembrane acyltransferases and is required to generate active Hedgehog protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1106881108

Lipid nanocarriers improve paclitaxel transport throughout human intestinal epithelial cells by using vesicle-mediated transcytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1106881108

Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1106881108

Delta-promoted filopodia mediate long-range lateral inhibition in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1106881108

Hedgehog creates a gradient of DPP activity in Drosophila wing imaginal discs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1106881108

Drosophila glypicans control the cell-to-cell movement of Hedgehog by a dynamin-independent process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1106881108

Distinct roles of Central missing and Dispatched in sending the Hedgehog signal

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

Directionality of wingless protein transport influences epidermal patterning in the Drosophila embryo.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

Induction of Drosophila eye development by decapentaplegic.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

Visualization of gene expression in living adult Drosophila.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3150953

28 October 2018

Identifiers

DOI

10.1073/PNAS.1106881108

1 reference

31 July 2017

0 references

1 reference

31 July 2017

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