(Q37965371)

26 August 2017

title

Establishing a laboratory animal model from a transgenic animal: RasH2 mice as a model for carcinogenicity studies in regulatory science (English)

1 reference

26 August 2017

K Urano

1

1 reference

26 August 2017

N Tamaoki

series ordinal

2

1 reference

26 August 2017

T Nomura

series ordinal

3

1 reference

26 August 2017

publication date

6 December 2011

1 reference

26 August 2017

1 reference

26 August 2017

volume

49

1 reference

26 August 2017

issue

1

1 reference

26 August 2017

page(s)

16-23

1 reference

A critical review of the effectiveness of rodent pharmaceutical carcinogenesis testing in predicting for human risk

26 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1177%2F0300985811430318

A point mutation in the last intron responsible for increased expression and transforming activity of the c-Ha-ras oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985811430318

Cancer risk assessment approaches at the FDA/CDER: Is the era of the 2-year bioassay drawing to a close?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985811430318

Carcinogenic susceptibility of rasH2 mice to troglitazone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985811430318

Alternative mouse models for carcinogenicity assessment: industry use and issues with pathology interpretation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985811430318

The utility of genetically modified mouse assays for identifying human carcinogens: a basic understanding and path forward. The Alternatives to Carcinogenicity Testing Committee ILSI HESI

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985811430318

Carcinogenic comparative study on rasH2 mice produced by two breeding facilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985811430318

Susceptibility of transgenic mice carrying human prototype c-Ha-ras gene in a short-term carcinogenicity study of vinyl carbamate and ras gene analyses of the induced tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985811430318

Pathological features of spontaneous and induced tumors in transgenic mice carrying a human prototype c-Ha-ras gene used for six-month carcinogenicity studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985811430318

An industry perspective on the utility of short-term carcinogenicity testing in transgenic mice in pharmaceutical development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985811430318

PCR method for genotyping and zygosity-testing of RasH2 transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985811430318

CB6F1-rasH2 mouse: overview of available data

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985811430318

Validation of transgenic mice carrying the human prototype c-Ha-ras gene as a bioassay model for rapid carcinogenicity testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0300985811430318

21 January 2018

Identifiers

DOI

10.1177/0300985811430318

1 reference

26 August 2017

1 reference