(Q37968218)

26 August 2017

Tackling endothelial dysfunction by modulating NOS uncoupling: new insights into its pathogenesis and therapeutic possibilities (English)

1 reference

26 August 2017

0 references

0 references

Rinrada Kietadisorn

1

1 reference

PubMed ID

22167522

26 August 2017

Rio P Juni

series ordinal

2

1 reference

PubMed ID

22167522

26 August 2017

An L Moens

series ordinal

3

1 reference

26 August 2017

13 December 2011

1 reference

American Journal of Physiology - Endocrinology and Metabolism

26 August 2017

1 reference

26 August 2017

302

1 reference

26 August 2017

5

1 reference

26 August 2017

E481-95

1 reference

Asymmetric dimethylarginine causes hypertension and cardiac dysfunction in humans and is actively metabolized by dimethylarginine dimethylaminohydrolase

26 August 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Oral L-arginine improves endothelium-dependent dilatation and reduces monocyte adhesion to endothelial cells in young men with coronary artery disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Role of xanthine oxidase and neutrophils in ischemia-reperfusion injury in rabbit lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Flow-mediated and reflex changes in large peripheral artery tone in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Association of plasma asymmetrical dimethylarginine (ADMA) with elevated vascular superoxide production and endothelial nitric oxide synthase uncoupling: implications for endothelial function in human atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Arginase pathway in human endothelial cells in pathophysiological conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Stoichiometric relationships between endothelial tetrahydrobiopterin, endothelial NO synthase (eNOS) activity, and eNOS coupling in vivo: insights from transgenic mice with endothelial-targeted GTP cyclohydrolase 1 and eNOS overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Three different oxygen-induced radical species in endothelial nitric-oxide synthase oxygenase domain under regulation by L-arginine and tetrahydrobiopterin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Microvascular oxygenation, oxidative stress, NO suppression and superoxide dismutase during postischemic reperfusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Oral L-arginine improves endothelial function in healthy individuals older than 70 years

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

The L-arginine paradox: Importance of the L-arginine/asymmetrical dimethylarginine ratio

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Homocysteine lowering and cardiovascular events after acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Human macrophage-induced vascular smooth muscle cell apoptosis requires NO enhancement of Fas/Fas-L interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Atrial expression of endothelial nitric oxide synthase in patients with and without atrial fibrillation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

In vivo measurement of oxygen-derived free radicals during reperfusion injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Endothelial dihydrofolate reductase: critical for nitric oxide bioavailability and role in angiotensin II uncoupling of endothelial nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Tetrahydrobiopterin: regulator of endothelial nitric oxide synthase in vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Oxidized LDL inhibits vascular endothelial growth factor-induced endothelial cell migration by an inhibitory effect on the Akt/endothelial nitric oxide synthase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Modulation of electron transport protects cardiac mitochondria and decreases myocardial injury during ischemia and reperfusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Blood levels of homocysteine and increased risks of cardiovascular disease: causal or casual?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Oral L-arginine improves endothelium-dependent dilation in hypercholesterolemic young adults.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Chronic treatment with tetrahydrobiopterin reverses endothelial dysfunction and oxidative stress in hypercholesterolaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterin-eNOS stoichiometry and biopterin redox status: insights from cells with tet-regulated GTP cyclohydrolase I expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Transplantation of endothelial progenitor cells overexpressing endothelial nitric oxide synthase enhances inhibition of neointimal hyperplasia and restores endothelium-dependent vasodilatation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Role of endothelial dysfunction in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Tetrahydrobiopterin attenuates homocysteine induced endothelial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Vascular repair by circulating endothelial progenitor cells: the missing link in atherosclerosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Folate improves endothelial function in coronary artery disease: an effect mediated by reduction of intracellular superoxide?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Myocardial ischemia results in tetrahydrobiopterin (BH4) oxidation with impaired endothelial function ameliorated by BH4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Cigarette smoke-mediated oxidative stress, shear stress, and endothelial dysfunction: role of VEGFR2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

VEGFR-2 inhibition augments cigarette smoke-induced oxidative stress and inflammatory responses leading to endothelial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Changes in caveolin-1 expression and vasoreactivity in the aorta and corpus cavernosum of fructose and streptozotocin-induced diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Hydroxy-methylglutaryl-coenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Critical role of the nitric oxide/reactive oxygen species balance in endothelial progenitor dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Response of human coronary arteries to aggregating platelets: importance of endothelium-derived relaxing factor and prostanoids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Improvement in left ventricular remodeling by the endothelial nitric oxide synthase enhancer AVE9488 after experimental myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

The eNOS enhancer AVE 9488: a novel cardioprotectant against ischemia reperfusion injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Hyperglycemia induces apoptosis of pancreatic islet endothelial cells via reactive nitrogen species-mediated Jun N-terminal kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

S-nitroso human serum albumin treatment reduces ischemia/reperfusion injury in skeletal muscle via nitric oxide release

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Nitric oxide: a key factor behind the dysfunctionality of endothelial progenitor cells in diabetes mellitus type-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Nitric oxide overproduction derived from inducible nitric oxide synthase increases cardiomyocyte apoptosis in human atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Oxidative stress and hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

HMG-CoA reductase inhibitor increases GTP cyclohydrolase I mRNA and tetrahydrobiopterin in vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Homocysteine impairs coronary artery endothelial function by inhibiting tetrahydrobiopterin in patients with hyperhomocysteinemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Tetrahydrobiopterin improves endothelium-dependent vasodilation in chronic smokers : evidence for a dysfunctional nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Tetrahydrobiopterin improves aging-related impairment of endothelium-dependent vasodilation through increase in nitric oxide production

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Mechanisms underlying endothelial dysfunction in diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

eNOS, metabolic syndrome and cardiovascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Accuracy of quantitative coronary angiography with computed tomography and its dependency on plaque composition: plaque composition and accuracy of cardiac CT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Interaction of 5-methyltetrahydrofolate and tetrahydrobiopterin on endothelial function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Nitric oxide as a signaling molecule in the vascular system: an overview.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Estrogen-mediated, endothelial nitric oxide synthase-dependent mobilization of bone marrow-derived endothelial progenitor cells contributes to reendothelialization after arterial injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

C-reactive protein: risk marker or mediator in atherothrombosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Expression of nitric oxide synthase in skeletal muscle: a novel role for nitric oxide as a modulator of insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Endothelial NO synthase overexpression inhibits lesion formation in mouse model of vascular remodeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Hyperglycemia reduces coronary collateral blood flow through a nitric oxide-mediated mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Protection from reoxygenation injury by inhibition of rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

A myocardial Nox2 containing NAD(P)H oxidase contributes to oxidative stress in human atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Endothelial function and coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Impairment of endothelium-dependent vasorelaxation in experimental atherosclerosis is dependent on gender.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Genetic deficiency of inducible nitric oxide synthase reduces atherosclerosis and lowers plasma lipid peroxides in apolipoprotein E-knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Atheroprotective effects of neuronal nitric oxide synthase in apolipoprotein e knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Heat shock protein 90 transfection reduces ischemia-reperfusion-induced myocardial dysfunction via reciprocal endothelial NO synthase serine 1177 phosphorylation and threonine 495 dephosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: implications for uncoupling endothelial nitric-oxide synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Statin-induced improvement of endothelial progenitor cell mobilization, myocardial neovascularization, left ventricular function, and survival after experimental myocardial infarction requires endothelial nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Methods for evaluating endothelial function: a position statement from the European Society of Cardiology Working Group on Peripheral Circulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Impairment of both nitric oxide-mediated and EDHF-type relaxation in small mesenteric arteries from rats with streptozotocin-induced diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Tetrahydrobiopterin deficiency and nitric oxide synthase uncoupling contribute to atherosclerosis induced by disturbed flow

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Inflammation in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Homocysteine lowering with folic acid and B vitamins in vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Homocysteine trials--clear outcomes for complex reasons

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Time-dependent inhibition and tetrahydrobiopterin depletion of endothelial nitric-oxide synthase caused by cigarettes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Gene transfer of endothelial nitric oxide synthase improves relaxation of carotid arteries from diabetic rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Oxidized low density lipoprotein impairs endothelial progenitor cells by regulation of endothelial nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition prevents endothelial NO synthase downregulation by atherogenic levels of native LDLs: balance between transcriptional and posttranscriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Circulating endothelial progenitor cells and clinical outcome in patients with congestive heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Plasma levels of nitrite/nitrate and platelet cGMP levels are decreased in patients with atrial fibrillation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

FcgammaRIIB mediates C-reactive protein inhibition of endothelial NO synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

High-dose folic acid pretreatment blunts cardiac dysfunction during ischemia coupled to maintenance of high-energy phosphates and reduces postreperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Flow-mediated vasodilation: a diagnostic instrument, or an experimental tool?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Tetrahydrobiopterin and cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Bi-modal dose-dependent cardiac response to tetrahydrobiopterin in pressure-overload induced hypertrophy and heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Targeting endothelial and myocardial dysfunction with tetrahydrobiopterin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Reversal of cardiac hypertrophy and fibrosis from pressure overload by tetrahydrobiopterin: efficacy of recoupling nitric oxide synthase as a therapeutic strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Mechanisms and potential therapeutic targets for folic acid in cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Does nitric oxide modulate mitochondrial energy generation and apoptosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser(1179).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Phosphoinositide 3-kinase signalling in the vascular system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Tetrahydrobiopterin depletion and NOS2 uncoupling contribute to heart failure-induced alterations in atrial electrophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Homocysteine, a thrombogenic agent, suppresses anticoagulant heparan sulfate expression in cultured porcine aortic endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Nitric oxide synthesis by cultured endothelial cells is modulated by flow conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Attenuation of angiotensin II signaling recouples eNOS and inhibits nonendothelial NOX activity in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Sirt1 modulates premature senescence-like phenotype in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Chronic oral supplementation with sepiapterin prevents endothelial dysfunction and oxidative stress in small mesenteric arteries from diabetic (db/db) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

C-reactive protein accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Tetrahydrobiopterin: a novel antihypertensive therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Atrial sources of reactive oxygen species vary with the duration and substrate of atrial fibrillation: implications for the antiarrhythmic effect of statins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Interactions of nitric oxide and peroxynitrite with low-density lipoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Induction of NAD(P)H oxidase by oxidized low-density lipoprotein in human endothelial cells: antioxidative potential of hydroxymethylglutaryl coenzyme A reductase inhibitor therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Leptin enhances the recruitment of endothelial progenitor cells into neointimal lesions after vascular injury by promoting integrin-mediated adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

L-arginine therapy in acute myocardial infarction: the Vascular Interaction With Age in Myocardial Infarction (VINTAGE MI) randomized clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Neuronal nitric oxide synthase regulates basal microvascular tone in humans in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Liver sinusoidal endothelial cells are responsible for nitric oxide modulation of resistance in the hepatic sinusoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Mice with gene disruption of both endothelial and neuronal nitric oxide synthase exhibit insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Chronic hypoxia increases endothelial nitric oxide synthase generation of nitric oxide by increasing heat shock protein 90 association and serine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Biosynthesis of tetrahydrobiopterin. Purification and characterization of 6-pyruvoyl-tetrahydropterin synthase from human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Abnormal biopterin metabolism is a major cause of impaired endothelium-dependent relaxation through nitric oxide/O2- imbalance in insulin-resistant rat aorta

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Uncoupled cardiac nitric oxide synthase mediates diastolic dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

C-reactive protein decreases endothelial nitric oxide synthase activity via uncoupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Functional consequences of the collagen/elastin switch in vascular remodeling in hyperhomocysteinemic wild-type, eNOS-/-, and iNOS-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Homocysteine impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Cigarette smoke extract inhibits angiogenesis of pulmonary artery endothelial cells: the role of calpain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

ADMA and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitamins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Atrial fibrillation impairs endothelial function of forearm vessels in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Mechanisms of salt-sensitive hypertension: role of inducible nitric oxide synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Impaired coronary vasodilation by magnetic resonance angiography is associated with advanced coronary artery calcification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Tetrahydrobiopterin biosynthesis, regeneration and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Endothelial dysfunction of coronary resistance arteries is improved by tetrahydrobiopterin in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Restoration of endothelium-dependent vasodilation after reperfusion injury by tetrahydrobiopterin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Cerebral blood flow regulation by nitric oxide: recent advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Control of systemic and pulmonary blood pressure by nitric oxide formed through neuronal nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Homocysteine induces oxidative stress by uncoupling of NO synthase activity through reduction of tetrahydrobiopterin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Neuronal nitric oxide synthase as a novel anti-atherogenic factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Mechanisms of homocysteine-induced oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Endothelial function and nitric oxide: clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Impaired NO-dependent vasodilation in patients with Type II (non-insulin-dependent) diabetes mellitus is restored by acute administration of folate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Folic acid supplementation normalizes the endothelial progenitor cell transcriptome of patients with type 1 diabetes: a case-control pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Endothelial dysfunction and vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Altered tetrahydrobiopterin metabolism in atherosclerosis: implications for use of oxidized tetrahydrobiopterin analogues and thiol antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

C-reactive protein attenuates endothelial progenitor cell survival, differentiation, and function: further evidence of a mechanistic link between C-reactive protein and cardiovascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Novel cardioprotective effects of tetrahydrobiopterin after anoxia and reoxygenation: Identifying cellular targets for pharmacologic manipulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

A self-fulfilling prophecy: C-reactive protein attenuates nitric oxide production and inhibits angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Oxidative stress, endothelial dysfunction and atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Inhibiting NOS blocks microvascular recruitment and blunts muscle glucose uptake in response to insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Arginine restores nitric oxide activity and inhibits monocyte accumulation after vascular injury in hypercholesterolemic rabbits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Influence of hyperhomocysteinemia on the cellular redox state--impact on homocysteine-induced endothelial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Antiatherosclerotic effects of small-molecular-weight compounds enhancing endothelial nitric-oxide synthase (eNOS) expression and preventing eNOS uncoupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Hyperglycemia induces inducible nitric oxide synthase gene expression and consequent nitrosative stress via c-Jun N-terminal kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

AVE3085, an enhancer of endothelial nitric oxide synthase, restores endothelial function and reduces blood pressure in spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Oxygen metabolism by endothelial nitric-oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Endothelial Progenitor Cell Dysfunction: A Novel Concept in the Pathogenesis of Vascular Complications of Type 1 Diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Effects of Oral Folic Acid Supplementation on Endothelial Function in Familial Hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Salt-induced hypertension in Dahl salt-resistant and salt-sensitive rats with NOS II inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

A Specific Role for eNOS-Derived Reactive Oxygen Species in Atherosclerosis Progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00540.2011

10.1152/AJPENDO.00540.2011

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference

PubMed ID

22167522