(Q37970012)

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G protein-coupled receptor signalling in the cardiac nuclear membrane: evidence and possible roles in physiological and pathophysiological function.

scientific article published on 19 December 2011

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19 January 2020

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G protein-coupled receptor signalling in the cardiac nuclear membrane: evidence and possible roles in physiological and pathophysiological function (English)

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19 January 2020

G protein-coupled receptor

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pathophysiology

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19 January 2020

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19 January 2020

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Artavazd Tadevosyan

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19 January 2020

George Vaniotis

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19 January 2020

Terence E Hébert

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19 January 2020

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19 December 2011

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19 January 2020

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Journal of Physiology

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19 January 2020

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19 January 2020

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19 January 2020

1313-1330

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19 January 2020

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Anatomical profiling of G protein-coupled receptor expression

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Long-term (2-year) clinical events following transthoracic intramyocardial gene transfer of VEGF-2 in no-option patients.

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Group I metabotropic glutamate receptor signalling and its implication in neurological disease

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Reconstitution of ionic channels from inner and outer membranes of mammalian cardiac nuclei

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A-kinase-interacting protein localizes protein kinase A in the nucleus

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Expression of endogenous nuclear bradykinin B2 receptors mediating signaling in immediate early gene activation.

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Nuclear import of insulin-like growth factor-binding protein-3 and -5 is mediated by the importin beta subunit

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Pathophysiology of gap junctions in heart disease

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Nuclear localization of angiotensinogen in astrocytes.

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Regional expression of CXCL12/CXCR4 in liver and hepatocellular carcinoma and cell-cycle variation during in vitro differentiation

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Regulation of RhoGEF proteins by G12/13-coupled receptors

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Activation of the intracellular renin-angiotensin system in cardiac fibroblasts by high glucose: role in extracellular matrix production

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

High-glucose-induced regulation of intracellular ANG II synthesis and nuclear redistribution in cardiac myocytes

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Endocytosis and signalling: intertwining molecular networks

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Chemokine receptor CXCR4 and early-stage non-small cell lung cancer: pattern of expression and correlation with outcome

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Mitochondrial and nuclear forms of Wnt13 are generated via alternative promoters, alternative RNA splicing, and alternative translation start sites

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Angiogenesis and the ischaemic heart

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Nuclear-delimited angiotensin receptor-mediated signaling regulates cardiomyocyte gene expression.

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

GPCR expression in the heart; "new" receptors in myocytes and fibroblasts

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Receptor activity-independent recruitment of betaarrestin2 reveals specific signalling modes

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Molecular restoration of beta-adrenergic receptor signaling improves contractile function of failing hearts

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Cell communications in the heart.

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Renin-angiotensin system component expression in the HL-1 atrial cell line and in a pig model of atrial fibrillation

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Angiogenin is translocated to the nucleus of HeLa cells and is involved in ribosomal RNA transcription and cell proliferation

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Cellular localization and regional distribution of an angiotensin II-forming chymase in the heart

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Identification of a gonadotropin-releasing hormone receptor orthologue in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Nuclear localization of vasoactive intestinal peptide (VIP) receptors in human breast cancer.

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Calcium and the endothelin-1 and alpha 1-adrenergic stimulated phosphatidylinositol cycle in cultured rat cardiomyocytes

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Nuclear GPCRs in cardiomyocytes: an insider's view of β-adrenergic receptor signaling

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Nuclear β-adrenergic receptors modulate gene expression in adult rat heart

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Opioid peptide gene expression primes cardiogenesis in embryonal pluripotent stem cells

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Nuclear opioid receptors activate opioid peptide gene transcription in isolated myocardial nuclei

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Protein kinase C signaling transduces endorphin-primed cardiogenesis in GTR1 embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

High glucose concentration stimulates intracellular renin activity and angiotensin II generation in rat mesangial cells

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Induction of angiogenesis by a fragment of human tyrosyl-tRNA synthetase

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Subcellular localization of beta-arrestins is determined by their intact N domain and the nuclear export signal at the C terminus

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Integrin signalling regulates the nuclear localization and function of the lysophosphatidic acid receptor-1 (LPA1) in mammalian cells

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Nuclear localization of the type 1 PTH/PTHrP receptor in rat tissues.

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Nuclear localization of the type 1 parathyroid hormone/parathyroid hormone-related peptide receptor in MC3T3-E1 cells: association with serum-induced cell proliferation

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Removal of the membrane-anchoring domain of epidermal growth factor leads to intracrine signaling and disruption of mammary epithelial cell organization

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Transcellular induction of neuropeptide Y expression by NT4 and BDNF

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Nuclear alpha1-adrenergic receptors signal activated ERK localization to caveolae in adult cardiac myocytes

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Subtype-specific alpha1- and beta-adrenoceptor signaling in the heart

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Preservation of intracellular renin expression is insufficient to compensate for genetic loss of secreted renin.

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Local angiotensin II aggravates cardiac remodeling in hypertension

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Myocyte redistribution of GRK2 and GRK5 in hypertensive, heart-failure-prone rats

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

A therapeutic target for prostate cancer based on angiogenin-stimulated angiogenesis and cancer cell proliferation

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Nuclear localization of G protein beta 5 and regulator of G protein signaling 7 in neurons and brain

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Intracrine signaling through lipid mediators and their cognate nuclear G-protein-coupled receptors: a paradigm based on PGE2, PAF, and LPA1 receptors.

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Intracellular distribution of endothelin-1 receptors in rat liver cells

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Autocrine and intracrine signaling for cardiogenesis in embryonic stem cells: a clue for the development of novel differentiating agents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382322

5 November 2018

A novel localization of the G-protein-coupled CysLT1 receptor in the nucleus of colorectal adenocarcinoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382322

5 November 2018

Intracrine PTHrP protects against serum starvation-induced apoptosis and regulates the cell cycle in MCF-7 breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382322

5 November 2018

Intracrine hepatopoietin potentiates AP-1 activity through JAB1 independent of MAPK pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382322

5 November 2018

Expression of angiotensinogen mRNA and protein in angiotensin II-dependent hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382322

5 November 2018

VEGF nuclear accumulation correlates with phenotypical changes in endothelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382322

5 November 2018

The nature of intracrine peptide hormone action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382322

5 November 2018

Endothelin-1 activates p38 mitogen-activated protein kinase and cytosolic phospholipase A2 in cat iris sphincter smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382322

5 November 2018

Nuclear location of PLA2-I in proliferative cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382322

5 November 2018

Novel opioid binding sites associated with nuclei of NG108-15 neurohybrid cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382322

5 November 2018

Competition between nuclear localization and secretory signals determines the subcellular fate of a single CUG-initiated form of FGF3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382322

5 November 2018

The calcium ion and cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382322

5 November 2018

The cardiac renin-angiotensin system: its possible role in cell communication and impulse propagation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382322

5 November 2018

Identification and subcellular distribution of muscarinic acetylcholine receptor-related proteins in rabbit corneal and Chinese hamster ovary cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382322

5 November 2018

Insulin binding sites on the nuclear envelope: potential relationship to mRNA metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382322

5 November 2018

IL-1 and its receptor are translocated to the nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382322

5 November 2018

Angiotensin-II-binding sites on hepatocyte nuclei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382322

5 November 2018

Detection of angiotensin I and II in cultured rat cardiac myocytes and fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382322

5 November 2018

Ion channels in the nuclear envelope

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Chloride channels in the nuclear membrane

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Platelet-derived endothelial cell growth factor/thymidine phosphorylase expression in normal tissues: An immunohistochemical study

1 reference

https://api.crossref.org/works/10.1113%2FJPHYSIOL.2011.222794

21 January 2018

Identification of three human renin mRNA isoforms from alternative tissue-specific transcriptional initiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382322

3 December 2018

Nuclear muscarinic acetylcholine receptors in corneal cells from rabbit

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear angiotensin receptors induce transcription of renin and angiotensinogen mRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Norepinephrine in neonatal rat ventricular myocytes: association with the cell nucleus and binding to nuclear alpha 1- and beta-adrenergic receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynorphin gene expression and release in the myocardial cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular distribution of adenylate cyclase in human cardiocytes determined by electron microscopic cytochemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An alternative transcript of the rat renin gene can result in a truncated prorenin that is transported into adrenal mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanical stretch and angiotensin II differentially upregulate the renin-angiotensin system in cardiac myocytes In vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endogenous angiogenin in endothelial cells is a general requirement for cell proliferation and angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The distribution and density of ET-1 and its receptors are different in human right and left ventricular endocardial endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of intracellular angiotensin II in vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic angiotensin II nuclear receptors and transcription of growth-related factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exogenous effects and endogenous production of endothelin in cardiac myocytes: potential significance in heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of intracellular interferon-gamma and interleukin-4 in whole blood T lymphocytes from patients with systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myocardial cell death in human diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neomycin inhibits the angiogenic activity of fibroblast and epidermal growth factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of a biological peptide pump to study chronic peptide hormone action in transgenic mice. Direct and indirect effects of angiotensin II on the heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear localization of type I parathyroid hormone/parathyroid hormone-related protein receptors in deer antler osteoclasts: evidence for parathyroid hormone-related protein and receptor activator of NF-kappaB-dependent effects on osteoclast formati

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An alpha1A-adrenergic-extracellular signal-regulated kinase survival signaling pathway in cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G protein-coupled receptors in and on the cell nucleus: a new signaling paradigm?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensin II: rapid localization in nuclei of smooth and cardiac muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensin II receptors in chromatin fragments generated by micrococcal nuclease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis, internalization, and localization of atrial natriuretic peptide in rat adrenal medulla

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a direct action of neuropeptide Y in the rat pituitary gland

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The molecular basis of neurotrophic keratitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of sarcolemma and nuclear membranes ET-1 receptors regulates transcellular calcium levels in heart and vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium-mediated translocation of cytosolic phospholipase A2 to the nuclear envelope and endoplasmic reticulum

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renin-angiotensin system and cell communication in the failing heart.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular angiotensin II regulates the inward calcium current in cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular actions of angiotensin II in vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue-specific expression of a rat renin transcript lacking the coding sequence for the prefragment and its stimulation by myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22183719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1113/JPHYSIOL.2011.222794

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22183719%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22183719%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

ResearchGate publication ID

0 references

Sitelinks

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Wikisource(0 entries)

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