(Q37971591)

26 August 2017

title

Proline metabolism and cancer (English)

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26 August 2017

James M Phang

1

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26 August 2017

Wei Liu

series ordinal

2

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26 August 2017

publication date

1 January 2012

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26 August 2017

published in

Frontiers in Bioscience

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26 August 2017

volume

17

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26 August 2017

page(s)

1835-1845

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Regulation and function of proline oxidase under nutrient stress

26 August 2017

cites work

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12 December 2020

The collagen receptor uPARAP/Endo180.

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12 December 2020

The metabolism of proline, a stress substrate, modulates carcinogenic pathways

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12 December 2020

A novel function for hydroxyproline oxidase in apoptosis through generation of reactive oxygen species

1 reference

12 December 2020

Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

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12 December 2020

Structure and Kinetics of Monofunctional Proline Dehydrogenase from Thermus thermophilus

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12 December 2020

The regulatory functions of proline and pyrroline-5-carboxylic acid

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12 December 2020

CD36, oxidized LDL and PPAR gamma: pathological interactions in macrophages and atherosclerosis

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12 December 2020

Fuel feeds function: energy metabolism and the T-cell response

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12 December 2020

Proline oxidase, a proapoptotic gene, is induced by troglitazone: evidence for both peroxisome proliferator-activated receptor gamma-dependent and -independent mechanisms

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12 December 2020

Wnt and PPARgamma signaling in osteoblastogenesis and adipogenesis

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12 December 2020

Proline oxidase induces apoptosis in tumor cells, and its expression is frequently absent or reduced in renal carcinomas

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12 December 2020

Tumor stroma and regulation of cancer development

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12 December 2020

microRNAs as oncogenes and tumor suppressors

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12 December 2020

Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers.

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12 December 2020

Mutations in PYCR1 cause cutis laxa with progeroid features

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12 December 2020

Redox regulation of the nutrient-sensitive raptor-mTOR pathway and complex

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12 December 2020

miR-23b targets proline oxidase, a novel tumor suppressor protein in renal cancer

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12 December 2020

Structural biology of proline catabolism

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12 December 2020

Regulation of human dihydrofolate reductase activity and expression

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12 December 2020

Proline metabolism and microenvironmental stress

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12 December 2020

Matrix metalloproteinases: regulators of the tumor microenvironment

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12 December 2020

Metabolic profiling reveals key metabolic features of renal cell carcinoma

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12 December 2020

Pro-MMP-2 activation by the PPARgamma agonist, ciglitazone, induces cell invasion through the generation of ROS and the activation of ERK.

1 reference

12 December 2020

Proline oxidase functions as a mitochondrial tumor suppressor in human cancers

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12 December 2020

Familial Hyperprolinemia, Cerebral Dysfunction and Renal Anomalies Occurring in a Family with Hereditary Nephropathy and Deafness

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12 December 2020

Oxidized low-density lipoproteins upregulate proline oxidase to initiate ROS-dependent autophagy

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12 December 2020

MicroRNAs as tumor suppressors

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12 December 2020

Hypoxia, inflammation, and the tumor microenvironment in metastatic disease

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12 December 2020

MnSOD inhibits proline oxidase-induced apoptosis in colorectal cancer cells.

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12 December 2020

Molecular characterisation of six patients with prolidase deficiency: identification of the first small duplication in the prolidase gene and of a mutation generating symptomatic and asymptomatic outcomes within the same family.

1 reference

12 December 2020

Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer.

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12 December 2020

MYC, microRNAs and glutamine addiction in cancers

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12 December 2020

Defining the role of mTOR in cancer

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12 December 2020

Cellular metabolic stress: considering how cells respond to nutrient excess.

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12 December 2020

Proline oxidase activates both intrinsic and extrinsic pathways for apoptosis: the role of ROS/superoxides, NFAT and MEK/ERK signaling

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12 December 2020

Coevolution of cancer and stromal cellular responses

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12 December 2020

Induction of glyoxylate cycle enzymes in rat liver upon food starvation

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12 December 2020

Overexpression of proline oxidase induces proline-dependent and mitochondria-mediated apoptosis.

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12 December 2020

Quantitative metabolome profiling of colon and stomach cancer microenvironment by capillary electrophoresis time-of-flight mass spectrometry.

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12 December 2020

Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma

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12 December 2020

A model for p53-induced apoptosis

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12 December 2020

Matrix metalloproteinases as modulators of inflammation and innate immunity

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12 December 2020

Response of a human colon adenocarcinoma (DLD-1) to X irradiation and mitomycin C in vivo

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12 December 2020

Role of PPAR-gamma in inflammation. Prospects for therapeutic intervention by food components

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12 December 2020

Brick by brick: metabolism and tumor cell growth

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12 December 2020

Role of autophagy in cancer: management of metabolic stress

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12 December 2020

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

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12 December 2020

Metabolism of Proline and of Hydroxyproline

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12 December 2020

Inflammation and cancer

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12 December 2020

Proline oxidase, encoded by p53-induced gene-6, catalyzes the generation of proline-dependent reactive oxygen species

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12 December 2020

The role of proteases in transforming growth factor-beta activation

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12 December 2020

Regulation of matrix metalloproteinase gene expression

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12 December 2020

Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK-ERK linkage

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12 December 2020

The metabolism of proline as microenvironmental stress substrate

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12 December 2020

Dermal collagen metabolism during tumor promotion with 12-O-tetradecanoylphorbol-13-acetate in mouse skin.

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12 December 2020

Purified human erythrocyte pyrroline-5-carboxylate reductase. Preferential oxidation of NADPH

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12 December 2020

Oncogenic alterations of metabolism

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12 December 2020

Targeting matrix metalloproteinases in inflammatory conditions.

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12 December 2020

Hypoxic tumor microenvironments reduce collagen I fiber density

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12 December 2020

The double-edged sword of autophagy modulation in cancer

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12 December 2020

Identifiers

DOI

10.2741/4022

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26 August 2017

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