(Q37973115)

26 August 2017

title

Considering RNAi experimental design in parasitic helminths (English)

1 reference

26 August 2017

Johnathan J Dalzell

1

1 reference

26 August 2017

Neil D Warnock

2

1 reference

26 August 2017

Paul McVeigh

3

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26 August 2017

Nikki J Marks

4

1 reference

26 August 2017

Angela Mousley

5

1 reference

26 August 2017

Louise Atkinson

6

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26 August 2017

Aaron G Maule

7

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26 August 2017

publication date

5 January 2012

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26 August 2017

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26 August 2017

volume

139

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26 August 2017

issue

5

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26 August 2017

page(s)

589-604

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Optimizing gene suppression in schistosomes using RNA interference.

26 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

RNA interference in schistosomes: machinery and methodology

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

RNA interference in Haemonchus contortus: suppression of beta-tubulin gene expression in L3, L4 and adult worms in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

RNA interference in parasitic nematodes of animals: a reality check?

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Polyethyleneimine (PEI) mediated siRNA gene silencing in the Schistosoma mansoni snail host, Biomphalaria glabrata

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

RNA interference: PCR strategies for the quantification of stable degradation-fragments derived from siRNA-targeted mRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Biological basis for restriction of microRNA targets to the 3' untranslated region in mammalian mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

flp gene disruption in a parasitic nematode reveals motor dysfunction and unusual neuronal sensitivity to RNA interference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Genomic insights into the origin of parasitism in the emerging plant pathogen Bursaphelenchus xylophilus

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Genome-wide RNAi screening in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Formation, regulation and evolution of Caenorhabditis elegans 3'UTRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Development of methods for RNA interference in the sheep gastrointestinal parasite, Trichostrongylus colubriformis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Mechanisms of dsRNA uptake in insects and potential of RNAi for pest control: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Small RNA asymmetry in RNAi: function in RISC assembly and gene regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Importance of quantitative PCR primer location for short interfering RNA efficacy determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Distinct populations of primary and secondary effectors during RNAi in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Decay of mRNAs targeted by RISC requires XRN1, the Ski complex, and the exosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Defining and assaying RNAi in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Activation of Nippostrongylus brasiliensis infective larvae is regulated by a pathway distinct from the hookworm Ancylostoma caninum

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Engineering broad root-knot resistance in transgenic plants by RNAi silencing of a conserved and essential root-knot nematode parasitism gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

siRNA-like double-stranded RNAs are specifically protected against degradation in human cell extract

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Kinetic PCR Analysis: Real-time Monitoring of DNA Amplification Reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Meloidogyne incognita: molecular and biochemical characterisation of a cathepsin L cysteine proteinase and the effect on parasitism following RNAi.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Real time quantitative PCR

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

SID-1 is a dsRNA-selective dsRNA-gated channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

A simple competitive RT-PCR assay for quantitation of HIV-1 subtype B and non-B RNA in plasma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

The SID-1 double-stranded RNA transporter is not selective for dsRNA length

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Effect of target secondary structure on RNAi efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Impact of target mRNA structure on siRNA silencing efficiency: A large-scale study

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Caveat of RNAi in plants: the off-target effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

RNAi-induced off-target effects in Drosophila melanogaster: frequencies and solutions

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

RNAi experiments in D. melanogaster: solutions to the overlooked problem of off-targets shared by independent dsRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Off-target effects dominate a large-scale RNAi screen for modulators of the TGF-β pathway and reveal microRNA regulation of TGFBR2

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Local RNA target structure influences siRNA efficacy: systematic analysis of intentionally designed binding regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Mfold web server for nucleic acid folding and hybridization prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Tissue specificity of Caenorhabditis elegans enhanced RNA interference mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Schistosoma japonicum: inhibition of Mago nashi gene expression by shRNA-mediated RNA interference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Necrotic cell death in C. elegans requires the function of calreticulin and regulators of Ca(2+) release from the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Real-time PCR for mRNA quantitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Genetic variation in parasitic nematodes and its implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Cytosine methylation regulates oviposition in the pathogenic blood fluke Schistosoma mansoni.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Distinct phases of siRNA synthesis in an endogenous RNAi pathway in C. elegans soma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

RNA interference in parasitic helminths: current situation, potential pitfalls and future prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Testing the efficacy of RNA interference in Haemonchus contortus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

RNAi and functional genomics in plant parasitic nematodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Transport of dsRNA into cells by the transmembrane protein SID-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

C. elegans dss-1 is functionally conserved and required for oogenesis and larval growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Development of an in vivo RNAi protocol to investigate gene function in the filarial nematode, Brugia malayi

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Toxicity in mice expressing short hairpin RNAs gives new insight into RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

A specific antibody to neuropeptide AF1 (KNEFIRFamide) recognizes a small subset of neurons in Ascaris suum: differences from Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

On the road to reading the RNA-interference code

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

RETRACTED: Secondary siRNAs result from unprimed RNA synthesis and form a distinct class

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Schistosome I/Lamides--a new family of bioactive helminth neuropeptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

The silencing of cysteine proteases in Fasciola hepatica newly excysted juveniles using RNA interference reduces gut penetration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Evaluation of RNA isolation methods and reference genes for RT-PCR analyses of rare target RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

RNA interference targeting cathepsin L and Z-like cysteine proteases of Onchocerca volvulus confirmed their essential function during L3 molting

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

New perspectives on host-parasite interplay by comparative transcriptomic and proteomic analyses of Schistosoma japonicum

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Identification of an RNA-dependent RNA polymerase in Drosophila establishes a common theme in RNA silencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Characterisation by RNAi of pioneer genes expressed in the dorsal pharyngeal gland cell of Heterodera glycines and the effects of combinatorial RNAi.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Effective delivery of a nematode-repellent peptide using a root-cap-specific promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

A PAL for Schistosoma mansoni PHM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Prediction of microRNAs affecting mRNA expression during retinal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

In vitro analyses of the production and activity of secondary small interfering RNAs in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

The modification of siRNA with 3' cholesterol to increase nuclease protection and suppression of native mRNA by select siRNA polyplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Gene silencing in Caenorhabditis elegans by transitive RNA interference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Attempts to establish RNA interference in the parasitic nematode Heligmosomoides polygyrus

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Molecular variation in trichostrongylid nematodes from sheep and cattle

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Schistosoma mansoni: the dicer gene and its expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Suppressing glucose transporter gene expression in schistosomes impairs parasite feeding and decreases survival in the mammalian host

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Defining the optimal parameters for hairpin-based knockdown constructs

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Off-target effects by siRNA can induce toxic phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Conservation of the global sex determination gene tra-1 in distantly related nematodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Analysis of chitin synthase function in a plant parasitic nematode, Meloidogyne artiellia, using RNAi.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

RNA interference in a cestode reveals specific silencing of selected highly expressed gene transcripts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

A new mathematical model for relative quantification in real-time RT-PCR

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Schistosoma mansoni: evaluation of an RNAi-based treatment targeting HGPRTase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Calreticulin, a calcium-binding molecular chaperone, is required for stress response and fertility in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Crystal structures of RNase H bound to an RNA/DNA hybrid: substrate specificity and metal-dependent catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Efficacy and specificity of RNA interference in larval life-stages of Ostertagia ostertagi.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Two hypotheses to explain why RNA interference does not work in animal parasitic nematodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Ingestion of double-stranded RNA by preparasitic juvenile cyst nematodes leads to RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Double-stranded RNA is internalized by scavenger receptor-mediated endocytosis in Drosophila S2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Exploring systemic RNA interference in insects: a genome-wide survey for RNAi genes in Tribolium

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

A protein sensor for siRNA asymmetry

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

RNA major groove modifications improve siRNA stability and biological activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

RNA interference in Lepidoptera: an overview of successful and unsuccessful studies and implications for experimental design.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

AtXRN4 degrades mRNA in Arabidopsis and its substrates include selected miRNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Enzymatic degradation by the sera of various animal species of penicillium chrysogenum mycophage double-stranded RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Short interfering RNA-mediated knockdown of drosha and pasha in undifferentiated Meloidogyne incognita eggs leads to irregular growth and embryonic lethality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Detection of siRNA induced mRNA silencing by RT-qPCR: considerations for experimental design

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

RNAi effector diversity in nematodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Non-nematode-derived double-stranded RNAs induce profound phenotypic changes in Meloidogyne incognita and Globodera pallida infective juveniles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Error propagation in relative real-time reverse transcription polymerase chain reaction quantification models: the balance between accuracy and precision.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Short interfering RNA-mediated gene silencing in Globodera pallida and Meloidogyne incognita infective stage juveniles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

A genome-scale shRNA resource for transgenic RNAi in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Enhanced neuronal RNAi in C. elegans using SID-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

In situ hybridization of neuropeptide-encoding transcripts afp-1, afp-3, and afp-4 in neurons of the nematode Ascaris suum

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

A comparative chemogenomics strategy to predict potential drug targets in the metazoan pathogen, Schistosoma mansoni

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

The 26S proteasome in Schistosoma mansoni: bioinformatics analysis, developmental expression, and RNA interference (RNAi) studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Redefining regulation of DNA methylation by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Phenotypic screen of early-developing larvae of the blood fluke, schistosoma mansoni, using RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

RNA interference of Schistosoma mansoni cathepsin D, the apical enzyme of the hemoglobin proteolysis cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Off-target effects associated with long dsRNAs in Drosophila RNAi screens

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

RNA interference-based therapeutics for human immunodeficiency virus HIV-1 treatment: synthetic siRNA or vector-based shRNA?

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

RNA interference in Schistosoma mansoni schistosomula: selectivity, sensitivity and operation for larger-scale screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Regulation of protein synthesis by mRNA structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

Factors affecting susceptibility to RNA interference in Haemonchus contortus and in vivo silencing of an H11 aminopeptidase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

7 January 2021

Host-generated double stranded RNA induces RNAi in plant-parasitic nematodes and protects the host from infection

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

7 January 2021

Localisation of Globodera pallida FMRFamide-related peptide encoding genes using in situ hybridisation

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

7 January 2021

DNA methylation: Bisulphite modification and analysis

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

7 January 2021

Peroxiredoxins from the plant parasitic root-knot nematode, Meloidogyne incognita, are required for successful development within the host

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

7 January 2021

The development of Haemonchus contortus in vitro. I. The effect of pH and pCO2 on the rate of development to the fourth-stage larva

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

7 January 2021

Gene silencing in Echinococcus multilocularis protoscoleces using RNA interference

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

7 January 2021

https://api.crossref.org/works/10.1017%2FS0031182011001946

1 reference

7 January 2021

Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors

1 reference

https://api.crossref.org/works/10.1017%2FS0031182011001946

7 January 2021

10.1017/S0031182011001946

Identifiers

DOI

1 reference

release_fsp3c3kstrafrd6c7fwi3o7bly

26 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fsp3c3kstrafrd6c7fwi3o7bly

24 November 2022

mapped directly with Wikidata item

1 reference