(Q37974525)

26 August 2017

Type I interferons: beneficial in Th1 and detrimental in Th17 autoimmunity (English)

1 reference

26 August 2017

Robert C Axtell

1

1 reference

PMCID

5478162

26 August 2017

Chander Raman

series ordinal

2

1 reference

PMCID

5478162

26 August 2017

Lawrence Steinman

series ordinal

3

1 reference

26 August 2017

1 April 2013

1 reference

Clinical Reviews in Allergy & Immunology

26 August 2017

1 reference

26 August 2017

44

1 reference

26 August 2017

2

1 reference

26 August 2017

114-120

1 reference

https://scigraph.springernature.com/pub.10.1007/s12016-011-8296-5

26 August 2017

0 references

cites work

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Immunotherapeutic effects of IL-7 during a chronic viral infection in mice

6 September 2017

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Suppression of inflammation in ulcerative colitis by interferon-β-1a is accompanied by inhibition of IL-13 production

6 September 2017

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Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

6 September 2017

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6 September 2017

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IFNβ-1b may severely exacerbate Japanese optic-spinal MS in neuromyelitis optica spectrum

6 September 2017

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Humoral autoimmunity in multiple sclerosis

6 September 2017

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T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis

6 September 2017

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IL-17 activates the canonical NF-kappaB signaling pathway in autoimmune B cells of BXD2 mice to upregulate the expression of regulators of G-protein signaling 16.

6 September 2017

1 reference

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Heterogeneous, longitudinally stable molecular signatures in response to interferon-beta

6 September 2017

1 reference

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A type I interferon signature in monocytes is associated with poor response to interferon-beta in multiple sclerosis

6 September 2017

1 reference

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Recent advances in the genetics of autoimmune disease

6 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Interleukin-17 causes neutrophil mediated inflammation in ovalbumin-induced uveitis in DO11.10 mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice

6 September 2017

1 reference

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Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: a phase II, double-blind, placebo-controlled, randomised, dose-ranging study

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Polymorphisms of the IL12B and IL23R genes are associated with psoriasis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

IL-23 is required for neutrophil homeostasis in normal and neutrophilic mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Using measurements of neutralizing antibodies: the challenge of IFN-beta therapy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Rheumatoid arthritis subtypes identified by genomic profiling of peripheral blood cells: assignment of a type I interferon signature in a subpopulation of patients.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Plasmacytoid predendritic cells initiate psoriasis through interferon-alpha production.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Interferon regulatory factor 1 (IRF-1) and IRF-2 distinctively up-regulate gene expression and production of interleukin-7 in human intestinal epithelial cells.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

A randomized, controlled trial of interferon-beta-1a (Avonex(R)) in patients with rheumatoid arthritis: a pilot study [ISRCTN03626626

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Interferon and granulopoiesis signatures in systemic lupus erythematosus blood

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

A role for humoral mechanisms in the pathogenesis of Devic's neuromyelitis optica

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Immunologic therapy of multiple sclerosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

IFN-gamma-dependent IL-7 gene regulation in keratinocytes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Interleukin-7 permits Th1/Tc1 maturation and promotes ex vivo expansion of cord blood T cells: a critical step toward adoptive immunotherapy after cord blood transplantation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Efficacy and safety of ABT-874, a monoclonal anti-interleukin 12/23 antibody, for the treatment of chronic plaque psoriasis: 36-week observation/retreatment and 60-week open-label extension phases of a randomized phase II trial.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Preferential increase of B-cell activating factor in the cerebrospinal fluid of neuromyelitis optica in a white population

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Interferon Beta treatment in neuromyelitis optica: increase in relapses and aquaporin 4 antibody titers

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Adjuvant treatment suppresses IL-17 production by T cell-independent myeloid sources in nonobese diabetic mice.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

New-onset psoriasis following treatment with pegylated interferon-alpha 2b and ribavirin for chronic hepatitis C.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

IFN-beta inhibits human Th17 cell differentiation

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

T-helper 17 cells expand in multiple sclerosis and are inhibited by interferon-beta.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Neuromyelitis optica with clinical and histopathological involvement of the brain.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Induction of genes mediating interferon-dependent extracellular trap formation during neutrophil differentiation

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

In psoriasis lesional skin the type I interferon signaling pathway is activated, whereas interferon-alpha sensitivity is unaltered

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5478162

Distinct and Nonredundant In Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12016-011-8296-5

Different responses to interferon beta-1b treatment in patients with neuromyelitis optica and multiple sclerosis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12016-011-8296-5

Variation in interleukin 7 receptor α chain (IL7R) influences risk of multiple sclerosis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12016-011-8296-5

Type I interferons as anti-inflammatory mediators

21 January 2018

1 reference

12 December 2020

Intrathecal activation of the IL-17/IL-8 axis in opticospinal multiple sclerosis

1 reference

12 December 2020

Exacerbation of psoriasis by interferon-alpha therapy for hepatitis C

1 reference

12 December 2020

Type I IFNs inhibit human dendritic cell IL-12 production and Th1 cell development

1 reference

12 December 2020

Clinical trial: a multicentre, randomized, double-blind, placebo-controlled, dose-finding, phase II study of subcutaneous interferon-beta-la in moderately active ulcerative colitis

1 reference

12 December 2020

Interferon-beta increases BAFF levels in multiple sclerosis: implications for B cell autoimmunity

1 reference

12 December 2020

Interferon beta-1b exacerbates multiple sclerosis with severe optic nerve and spinal cord demyelination

1 reference

12 December 2020

Human Th17 cells comprise heterogeneous subsets including IFN-gamma-producing cells with distinct properties from the Th1 lineage

1 reference

12 December 2020

Interferon-beta mediates opposing effects on interferon-gamma-dependent Interleukin-12 p70 secretion by human monocyte-derived dendritic cells

1 reference

12 December 2020

Verrucous psoriasis in a patient with chronic C hepatitis treated with interferon

1 reference

12 December 2020

New-onset psoriasis in a patient treated with interferon beta-1a

1 reference

12 December 2020

Beta interferon restricts the inflammatory potential of CD4+ cells through the boost of the Th2 phenotype, the inhibition of Th17 response and the prevalence of naturally occurring T regulatory cells

1 reference

12 December 2020

Ciclosporin treatment of psoriasis in a patient with chronic hepatitis C

1 reference

12 December 2020

CD8(+) T cell-mediated skin disease in mice lacking IRF-2, the transcriptional attenuator of interferon-alpha/beta signaling

1 reference

12 December 2020

Development of extensive brain lesions following interferon beta therapy in relapsing neuromyelitis optica and longitudinally extensive myelitis

1 reference

12 December 2020

CNS demyelination during anti–tumor necrosis factor alpha therapy

1 reference

12 December 2020

Cutaneous ulcerations and pustular psoriasis flare caused by recombinant interferon beta injections in patients with multiple sclerosis

1 reference

12 December 2020

Concomitant vitiligo and psoriasis in a patient treated with interferon alfa-2a for chronic hepatitis B infection

1 reference

12 December 2020

Psoriasis during interferon beta treatment for multiple sclerosis

1 reference

12 December 2020

10.1007/S12016-011-8296-5

Identifiers

DOI

1 reference

26 August 2017

1 reference

26 August 2017

1 reference

PMCID

5478162