(Q37975053)

26 August 2017

Fibroblast activation protein: A potential therapeutic target in cancer (English)

1 reference

26 August 2017

Rui Liu

1

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26 August 2017

Hui Li

2

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26 August 2017

Liang Liu

3

1 reference

26 August 2017

Jinpu Yu

4

1 reference

26 August 2017

Xiubao Ren

5

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26 August 2017

1 February 2012

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Cancer Biology and Therapy

26 August 2017

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26 August 2017

13

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26 August 2017

3

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26 August 2017

123-129

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Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

26 August 2017

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Fibroblast activation protein: purification, epitope mapping and induction by growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

A 170-kDa membrane-bound protease is associated with the expression of invasiveness by human malignant melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Mouse fibroblast-activation protein--conserved Fap gene organization and biochemical function as a serine protease

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Seprase complexes in cellular invasiveness.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Molecular cloning of seprase: a serine integral membrane protease from human melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Identification and characterization of the promoter of fibroblast activation protein

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair-deficient malignant glioma xenograft

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Effect of fibroblast activation protein and alpha2-antiplasmin cleaving enzyme on collagen types I, III, and IV.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-α

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Ala657 and conserved active site residues promote fibroblast activation protein endopeptidase activity via distinct mechanisms of transition state stabilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

The gene for fibroblast activation protein alpha (FAP), a putative cell surface-bound serine protease expressed in cancer stroma and wound healing, maps to chromosome band 2q23

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Fibroblast activation protein is expressed by rheumatoid myofibroblast-like synoviocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Fibroblast activation protein alpha is expressed by chondrocytes following a pro-inflammatory stimulus and is elevated in osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Fibroblast activation protein and chronic liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Fibroblast activation protein: a serine protease expressed at the remodeling interface in idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Cell surface glycoprotein of reactive stromal fibroblasts as a potential antibody target in human epithelial cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Histogenesis-specific expression of fibroblast activation protein and dipeptidylpeptidase-IV in human bone and soft tissue tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Fibroblast-activation protein: a single marker that confidently differentiates morpheaform/infiltrative basal cell carcinoma from desmoplastic trichoepithelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Fibroblast activation protein alpha identifies mesenchymal stromal cells from human bone marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Antiplasmin-cleaving enzyme is a soluble form of fibroblast activation protein

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

A novel plasma proteinase potentiates alpha2-antiplasmin inhibition of fibrin digestion

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Seprase, a membrane-bound protease, alleviates the serum growth requirement of human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Immunotherapy targeting fibroblast activation protein inhibits tumor growth and increases survival in a murine colon cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

TGF-beta induces fibroblast activation protein expression; fibroblast activation protein expression increases the proliferation, adhesion, and migration of HO-8910PM [corrected].

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Fibroblast activation protein and its relationship to clinical outcome in pancreatic adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Seprase: an overview of an important matrix serine protease

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

FAPalpha, a surface peptidase expressed during wound healing, is a tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Differential gene expression in tumorigenic and nontumorigenic HeLa x normal human fibroblast hybrid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Stromal expression of fibroblast activation protein/seprase, a cell membrane serine proteinase and gelatinase, is associated with longer survival in patients with invasive ductal carcinoma of breast

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

The evolving concept of tumor microenvironments

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

FAP-overexpressing fibroblasts produce an extracellular matrix that enhances invasive velocity and directionality of pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Fibroblast activation protein increases apoptosis, cell adhesion, and migration by the LX-2 human stellate cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Molecular proximity of seprase and the urokinase-type plasminogen activator receptor on malignant melanoma cell membranes: dependence on beta1 integrins and the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

A novel protease-docking function of integrin at invadopodia

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Expression and role of the cell surface protease seprase/fibroblast activation protein-α (FAP-α) in astroglial tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Fibroblast activation protein-α promotes tumor growth and invasion of breast cancer cells through non-enzymatic functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Seprase promotes rapid tumor growth and increased microvessel density in a mouse model of human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Expression of fibroblast activation proteins in corneal stromal neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

PT-100, a small molecule dipeptidyl peptidase inhibitor, has potent antitumor effects and augments antibody-mediated cytotoxicity via a novel immune mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Hematopoietic stimulation by a dipeptidyl peptidase inhibitor reveals a novel regulatory mechanism and therapeutic treatment for blood cell deficiencies

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Phase II trial of single agent Val-boroPro (Talabostat) inhibiting Fibroblast Activation Protein in patients with metastatic colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Phase II trial of talabostat and docetaxel in advanced non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Stromal antigen targeting by a humanised monoclonal antibody: an early phase II trial of sibrotuzumab in patients with metastatic colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Effective immunoconjugate therapy in cancer models targeting a serine protease of tumor fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Photodynamic molecular beacon triggered by fibroblast activation protein on cancer-associated fibroblasts for diagnosis and treatment of epithelial cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Evaluation of the tumor targeting of a FAPα-based doxorubicin prodrug

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Cancer associated fibroblasts promote tumor growth and metastasis by modulating the tumor immune microenvironment in a 4T1 murine breast cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

A new tumor vaccine: FAPτ-MT elicits effective antitumor response by targeting indolamine2,3-dioxygenase in antigen presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Tumor-specific crosslinking of GITR as costimulation for immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

The road to integrative cancer therapies: emergence of a tumor-associated fibroblast protease as a potential therapeutic target in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.13.3.18696

21 January 2018

Identifiers

DOI

10.4161/CBT.13.3.18696

1 reference

26 August 2017

1 reference