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Transcriptional mechanisms that regulate T helper 1 cell differentiation.
scientific article published on 10 January 2012
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PMC publication ID
3319510
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22240120%20AND%20SRC:MED&resulttype=core&format=json
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20 January 2020
title
Transcriptional mechanisms that regulate T helper 1 cell differentiation
(English)
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Europe PubMed Central
PMC publication ID
3319510
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22240120%20AND%20SRC:MED&resulttype=core&format=json
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20 January 2020
main subject
cell differentiation
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author
Kenneth J Oestreich
series ordinal
1
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3319510
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22240120%20AND%20SRC:MED&resulttype=core&format=json
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20 January 2020
author name string
Amy S Weinmann
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2
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3319510
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20 January 2020
publication date
10 January 2012
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3319510
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20 January 2020
published in
Current Opinion in Immunology
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3319510
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20 January 2020
volume
24
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3319510
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20 January 2020
issue
2
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Europe PubMed Central
PMC publication ID
3319510
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20 January 2020
page(s)
191-195
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3319510
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20 January 2020
cites work
Functional and epigenetic studies reveal multistep differentiation and plasticity of in vitro-generated and in vivo-derived follicular T helper cells
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PubMed Central
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Helper T-cell differentiation and plasticity: insights from epigenetics.
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6 September 2017
An essential role of the transcription factor GATA-3 for the function of regulatory T cells
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Encoding stability versus flexibility: lessons learned from examining epigenetics in T helper cell differentiation.
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6 September 2017
The lineage-defining factors T-bet and Bcl-6 collaborate to regulate Th1 gene expression patterns
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Regulatory T cells and Foxp3
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6 September 2017
Genomic views of STAT function in CD4+ T helper cell differentiation
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6 September 2017
Follicular helper CD4 T cells (TFH)
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PubMed Central
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6 September 2017
The Polycomb complex PRC2 and its mark in life
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6 September 2017
T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
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6 September 2017
Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors.
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PubMed Central
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6 September 2017
Effector T cell plasticity: flexibility in the face of changing circumstances
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6 September 2017
Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation
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PubMed Central
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6 September 2017
Differentiation of effector CD4 T cell populations (*)
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6 September 2017
Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells
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PubMed Central
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6 September 2017
Heterogeneity and plasticity of T helper cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
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6 September 2017
Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
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6 September 2017
CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner.
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PubMed Central
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6 September 2017
Plasticity of CD4+ T cell lineage differentiation.
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PubMed Central
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6 September 2017
How are T(H)1 and T(H)2 effector cells made?
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
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6 September 2017
Common themes emerge in the transcriptional control of T helper and developmental cell fate decisions regulated by the T-box, GATA and ROR families
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
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6 September 2017
Epigenetics and T helper 1 differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
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6 September 2017
Epigenetic control of T-helper-cell differentiation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
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6 September 2017
Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells
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PubMed Central
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6 September 2017
CD4 T cells: fates, functions, and faults
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6 September 2017
Identification of a distant T-bet enhancer responsive to IL-12/Stat4 and IFNgamma/Stat1 signals.
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PubMed Central
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6 September 2017
Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-gamma
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
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6 September 2017
Methylation of lysine 4 on histone H3: intricacy of writing and reading a single epigenetic mark
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PubMed Central
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6 September 2017
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
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PubMed Central
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6 September 2017
Long-range histone acetylation of the Ifng gene is an essential feature of T cell differentiation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
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6 September 2017
An epigenetic view of helper T cell differentiation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
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6 September 2017
Targeted recruitment of Set1 histone methylase by elongating Pol II provides a localized mark and memory of recent transcriptional activity
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
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6 September 2017
Active genes are tri-methylated at K4 of histone H3
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
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6 September 2017
T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
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6 September 2017
A novel transcription factor, T-bet, directs Th1 lineage commitment
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
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6 September 2017
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
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6 September 2017
Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
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PubMed Central
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6 September 2017
Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression
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PubMed Central
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14 September 2017
Coordinated but physically separable interaction with H3K27-demethylase and H3K4-methyltransferase activities are required for T-box protein-mediated activation of developmental gene expression
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
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14 September 2017
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
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28 September 2017
Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
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23 June 2018
T-bet's ability to regulate individual target genes requires the conserved T-box domain to recruit histone methyltransferase activity and a separate family member-specific transactivation domain
1 reference
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PubMed Central
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23 June 2018
EZH2 and histone 3 trimethyl lysine 27 associated with Il4 and Il13 gene silencing in Th1 cells
1 reference
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PubMed Central
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23 June 2018
T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
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23 June 2018
Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
retrieved
1 September 2018
The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
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1 September 2018
Sequential polarization and imprinting of type 1 T helper lymphocytes by interferon-gamma and interleukin-12.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319510
retrieved
1 September 2018
T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22240120
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22240120
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Chromatin remodeling of interleukin-17 (IL-17)-IL-17F cytokine gene locus during inflammatory helper T cell differentiation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22240120
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.COI.2011.12.004
1 reference
stated in
Europe PubMed Central
PMC publication ID
3319510
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22240120%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
PMC publication ID
3319510
1 reference
stated in
Europe PubMed Central
PMC publication ID
3319510
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22240120%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
PubMed publication ID
22240120
1 reference
stated in
Europe PubMed Central
PMC publication ID
3319510
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22240120%20AND%20SRC:MED&resulttype=core&format=json
retrieved
20 January 2020
ResearchGate publication ID
221742969
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