(Q37976705)

English

Metabolic agents that enhance ATP can improve cognitive functioning: a review of the evidence for glucose, oxygen, pyruvate, creatine, and L-carnitine

scientific article published on 10 August 2011

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

26 August 2017

1 reference

2 October 2023

Metabolic agents that enhance ATP can improve cognitive functioning: a review of the evidence for glucose, oxygen, pyruvate, creatine, and L-carnitine (English)

1 reference

Europe PubMed Central

PMC publication ID

26 August 2017

1 reference

27 September 2019

1 reference

7 November 2019

1 reference

18 November 2019

1 reference

4 July 2020

1 reference

14 August 2020

1 reference

15 August 2020

Sandra I Sünram-Lea

2

1 reference

Europe PubMed Central

PMC publication ID

26 August 2017

author name string

Lauren Owen

1

1 reference

Europe PubMed Central

PMC publication ID

26 August 2017

publication date

10 August 2011

1 reference

Europe PubMed Central

PMC publication ID

26 August 2017

1 August 2011

10 references

27 September 2019

4 November 2019

7 November 2019

18 November 2019

19 November 2019

4 July 2020

14 August 2020

15 August 2020

19 July 2022

2 October 2023

11 references

Europe PubMed Central

PMC publication ID

26 August 2017

27 September 2019

4 November 2019

7 November 2019

18 November 2019

19 November 2019

4 July 2020

14 August 2020

15 August 2020

19 July 2022

2 October 2023

3

1 reference

Europe PubMed Central

PMC publication ID

26 August 2017

8

1 reference

Europe PubMed Central

PMC publication ID

26 August 2017

735-755

1 reference

Europe PubMed Central

PMC publication ID

26 August 2017

copyright license

Creative Commons Attribution 3.0 Unported

10 references

Europe PubMed Central

27 September 2019

Europe PubMed Central

4 November 2019

Europe PubMed Central

7 November 2019

Europe PubMed Central

18 November 2019

Europe PubMed Central

19 November 2019

Europe PubMed Central

4 July 2020

Europe PubMed Central

14 August 2020

Europe PubMed Central

15 August 2020

Europe PubMed Central

19 July 2022

Europe PubMed Central

2 October 2023

copyright status

0 references

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Creatine and creatine kinase in health and disease--a bright future ahead?

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Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress

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6 September 2017

Oral creatine monohydrate supplementation improves brain performance: a double-blind, placebo-controlled, cross-over trial

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Factors influencing creatine loading into human skeletal muscle

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6 September 2017

Multinuclear magnetic resonance spectroscopy of high-energy phosphate metabolites in human brain following oral supplementation of creatine-monohydrate

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Pharmacokinetics of the dietary supplement creatine.

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Creatine kinase B-driven energy transfer in the brain is important for habituation and spatial learning behaviour, mossy fibre field size and determination of seizure susceptibility

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Effects of creatine on mental fatigue and cerebral hemoglobin oxygenation

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Mitochondrial dysfunction in bipolar disorder

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Delayed neuronal death

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Decreases in rat extracellular hippocampal glucose concentration associated with cognitive demand during a spatial task

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6 September 2017

Creatine supplementation--part I: performance, clinical chemistry, and muscle volume

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Prefrontal cortical-amygdalar metabolism in major depression

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6 September 2017

L-carnitine improves glucose disposal in type 2 diabetic patients

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6 September 2017

Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity

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6 September 2017

Glucose effects on cognition in adults with Down's syndrome

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6 September 2017

Pyruvate infusions into the septal area attenuate spontaneous alternation impairments induced by intraseptal morphine injections.

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6 September 2017

Oxidants, antioxidants, and the degenerative diseases of aging

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6 September 2017

Glucose enhancement of memory in patients with probable senile dementia of the Alzheimer's type.

1 reference

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6 September 2017

Healthy aging, memory subsystems and regional cerebral oxygen consumption.

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Metabolic and mechanical effects using L- and D-carnitine in working swine hearts

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Amnesia following the rupture and repair of an anterior communicating artery aneurysm

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6 September 2017

Memory enhancement in elderly humans: effects of glucose ingestion

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6 September 2017

Memory enhancement with posttraining intraventricular glucose injections in rats

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6 September 2017

Glucose enhancement of performance on memory tests in young and aged humans

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Special issues: glucose and the brain

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6 September 2017

Creatine: Biosynthesis, Regulation, and Function

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6 September 2017

Mitochondrial decay in aging

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Excercise physiology in health and disease

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14 September 2017

Carnitine--a known compound, a novel function in neural cells.

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Tricarboxylic acid cycle substrates prevent PARP-mediated death of neurons and astrocytes.

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23 June 2018

Creatine increases survival and suppresses seizures in the hypoxic immature rat.

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Brain blood flow restoration 'rescues' chronically damaged rat CA1 neurons.

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Hyperbaric Oxygenation and the Cognitive Functioning of the Aged

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23 June 2018

Glucose effects on memory: behavioral and pharmacological characteristics.

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Glucose modulation of memory storage processing

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Ca2+-dependent and Ca2+-independent glutamate release, energy status and cytosolic free Ca2+ concentration in isolated nerve terminals following metabolic inhibition: possible relevance to hypoglycaemia and anoxia.

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Acetyl-L-carnitine enhances acetylcholine release in the striatum and hippocampus of awake freely moving rats

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Effect of hypoglycemia on cerebral metabolism and carbon dioxide responsivity.

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Pharmacokinetics of IV and oral acetyl-L-carnitine in a multiple dose regimen in patients with senile dementia of Alzheimer type

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The effects of hyperbaric and normobaric oxygen on cognitive impairment in the elderly.

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Effects of advancing age on regional cerebral blood flow. Studies in normal subjects and subjects with risk factors for atherothrombotic stroke

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Dose-response investigation into glucose facilitation of memory performance and mood in healthy young adults.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

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Cognitive effects of creatine ethyl ester supplementation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Creatine supplementation does not improve cognitive function in young adults

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A study on the effects of 40% oxygen on addition task performance in three levels of difficulty and physiological signals

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1 September 2018

L-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial.

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1 September 2018

Creatine supplementation, sleep deprivation, cortisol, melatonin and behavior

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Inhibition of glycogenolysis in astrocytes interrupts memory consolidation in young chickens

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1 September 2018

Effect of creatine supplementation and sleep deprivation, with mild exercise, on cognitive and psychomotor performance, mood state, and plasma concentrations of catecholamines and cortisol

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Inhibition of the cerebral ischemic injury by ethyl pyruvate with a wide therapeutic window

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1 September 2018

Chemotherapy-induced allodinia: neuroprotective effect of acetyl-L-carnitine.

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1 September 2018

Severe cognitive impairment correlates with higher cerebrospinal fluid levels of lactate and pyruvate in a canine model of senile dementia.

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1 September 2018

Pyruvate administered after severe hypoglycemia reduces neuronal death and cognitive impairment

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1 September 2018

Thiols and the control of carbohydrate metabolism in cerebral tissues

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1 September 2018

Neuroprotective effects of L-carnitine in induced mitochondrial dysfunction

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1 September 2018

Decreased brain creatine levels in elderly apolipoprotein E epsilon 4 carriers

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Meta-analysis of double blind randomized controlled clinical trials of acetyl-L-carnitine versus placebo in the treatment of mild cognitive impairment and mild Alzheimer's disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Oxygen reverses deficits of cognitive function and memory and increased heart rate induced by acute severe isovolemic anemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Investigation into the significance of task difficulty and divided allocation of resources on the glucose memory facilitation effect.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Protection by pyruvate against transient forebrain ischemia in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Glucose facilitation of cognitive performance in healthy young adults: examination of the influence of fast-duration, time of day and pre-consumption plasma glucose levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Cognitive demand and blood glucose.

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1 September 2018

Glucose administration, heart rate and cognitive performance: effects of increasing mental effort.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Age- and dose-dependent glucose-induced increases in memory and attention in schizophrenia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Cognitive performance, hyperoxia, and heart rate following oxygen administration in healthy young adults.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Increase of total creatine in human brain after oral supplementation of creatine-monohydrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Glucose-induced increase in memory performance in patients with schizophrenia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Exogenous creatine delays anoxic depolarization and protects from hypoxic damage: dose-effect relationship

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Oxygen and cognitive performance: the temporal relationship between hyperoxia and enhanced memory.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Oxygen administration selectively enhances cognitive performance in healthy young adults: a placebo-controlled double-blind crossover study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Fuels for memory: the role of oxygen and glucose in memory enhancement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Monocarboxylates (pyruvate and lactate) as alternative energy substrates for the induction of long-term potentiation in rat hippocampal slices

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Effect of Glucose and Peripheral Glucose Regulation on Memory in the Elderly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Involvement of nitric oxide in low glucose-mediated inhibition of hippocampal long-term potentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Oxygen administration enhances memory formation in healthy young adults.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Effects of posttraining administration of glucose on retention of a habituation response in mice: participation of a central cholinergic mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Increased cerebrospinal fluid pyruvate levels in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

The effect of improved glycemic control on cognitive functions in the elderly patient with diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Posthypoxic amnesia: regional cerebral glucose consumption measured by positron emission tomography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Verbal learning and/or memory improves with glycemic control in older subjects with non-insulin-dependent diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Neuroprotective activity of acetyl-L-carnitine: studies in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

Cerebral blood flow and cerebrovascular CO2 reactivity in stroke-age normal controls.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257700

1 September 2018

The relation of strength of stimulus to rapidity of habit-formation

1 reference

https://api.crossref.org/works/10.3390%2FNU3080735

21 January 2018

Creatine Supplementation and Cognitive Performance in Elderly Individuals

1 reference

https://api.crossref.org/works/10.3390%2FNU3080735

21 January 2018

Anti-apoptotic effect of acetyl-l-carnitine and I-carnitine in primary cultured neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/22254121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose, insulin, and insulin-like growth factor I regulate the glycogen content of astroglia-rich primary cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/22254121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocyte survival in the absence of exogenous substrate: comparison of immature and mature cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22254121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary supplement creatine protects against traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/22254121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human visual evoked responses are related to heart rate

1 reference

https://pubmed.ncbi.nlm.nih.gov/22254121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Creatine reduces 3-nitropropionic-acid-induced cognitive and motor abnormalities in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22254121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective effects of acetyl-L-carnitine after stroke in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22254121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Skeletal muscle metabolism during short duration high-intensity exercise: influence of creatine supplementation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22254121

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/NU3080735

1 reference

Europe PubMed Central

PMC publication ID

26 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

26 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

26 August 2017

ResearchGate publication ID

0 references

Sitelinks

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