(Q37977006)

26 August 2017

title

The contribution of bone to whole-organism physiology (English)

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26 August 2017

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Gérard Karsenty

1

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26 August 2017

Mathieu Ferron

series ordinal

2

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26 August 2017

language of work or name

English

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publication date

18 January 2012

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26 August 2017

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26 August 2017

volume

481

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26 August 2017

issue

7381

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26 August 2017

page(s)

314-320

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https://scigraph.springernature.com/pub.10.1038/nature10763

26 August 2017

exact match

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cites work

Basic and clinical aspects of osteoporosis in inflammatory bowel disease.

1 reference

12 December 2020

Lower uncarboxylated osteocalcin concentrations in children with prediabetes is associated with beta-cell function

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12 December 2020

Lrp5 functions in bone to regulate bone mass

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12 December 2020

Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis

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12 December 2020

Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function

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12 December 2020

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance

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12 December 2020

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12 December 2020

Bone resorption by osteoclasts

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12 December 2020

Weight-reducing effects of the plasma protein encoded by the obese gene

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12 December 2020

Positional cloning of the mouse obese gene and its human homologue

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12 December 2020

Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation

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12 December 2020

Leptin regulates bone formation via the sympathetic nervous system

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12 December 2020

Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23

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12 December 2020

The neuroendocrine basis of anorexia nervosa and its impact on bone metabolism

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12 December 2020

Patients with high-bone-mass phenotype owing to Lrp5-T253I mutation have low plasma levels of serotonin

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12 December 2020

Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor

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12 December 2020

Endocrine regulation of energy metabolism by the skeleton

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12 December 2020

Impaired gastric acidification negatively affects calcium homeostasis and bone mass.

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12 December 2020

A unitary model for involutional osteoporosis: estrogen deficiency causes both type I and type II osteoporosis in postmenopausal women and contributes to bone loss in aging men.

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12 December 2020

Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis

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12 December 2020

Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling

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12 December 2020

Identification of SOCS-3 as a potential mediator of central leptin resistance

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12 December 2020

Update in serotonin and bone

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12 December 2020

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12 December 2020

Clinical relevance of changes in bone metabolism in inflammatory bowel disease

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12 December 2020

Improved glucose homeostasis in mice with muscle-specific deletion of protein-tyrosine phosphatase 1B.

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12 December 2020

Erythropoietin, erythropoiesis, and the kidney

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12 December 2020

Relation of serum serotonin levels to bone density and structural parameters in women

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12 December 2020

Low density lipoprotein receptor-related protein 5 (LRP5) mutations and osteoporosis, impaired glucose metabolism and hypercholesterolaemia

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12 December 2020

Leptin inhibits bone formation not only in rodents, but also in sheep

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12 December 2020

Levels of serotonin, sclerostin, bone turnover markers as well as bone density and microarchitecture in patients with high-bone-mass phenotype due to a mutation in Lrp5

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12 December 2020

Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass

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12 December 2020

A method for decarboxylation of gamma-carboxyglutamic acid in proteins. Properties of the decarboxylated gamma-carboxyglutamic acid protein from calf bone

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12 December 2020

Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance

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12 December 2020

Modulation of peripheral serotonin levels by novel tryptophan hydroxylase inhibitors for the potential treatment of functional gastrointestinal disorders

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12 December 2020

Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice

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12 December 2020

Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum

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12 December 2020

Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress

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12 December 2020

Protective effect of beta blockers in postmenopausal women: influence on fractures, bone density, micro and macroarchitecture

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12 December 2020

Minireview: fibroblast growth factor 23 in phosphate homeostasis and bone metabolism

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12 December 2020

Gene array analysis of Wnt-regulated genes in C3H10T1/2 cells

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12 December 2020

Endocrine regulation of male fertility by the skeleton

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12 December 2020

Neuropeptide Y knockout mice reveal a central role of NPY in the coordination of bone mass to body weight

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12 December 2020

Microelectrode studies on the acid microenvironment beneath adherent macrophages and osteoclasts*1

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12 December 2020

ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome

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12 December 2020

Serotonin neuronal function and selective serotonin reuptake inhibitor treatment in anorexia and bulimia nervosa

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12 December 2020

Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin

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12 December 2020

Relationship between central and peripheral serotonin indexes in depressed and suicidal psychiatric inpatients

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12 December 2020

Psychotropic drugs have contrasting skeletal effects that are independent of their effects on physical activity levels

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12 December 2020

High bone density due to a mutation in LDL-receptor-related protein 5

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12 December 2020

Leptin does not directly affect CNS serotonin neurons to influence appetite.

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12 December 2020

Efficacy of serotonin inhibition in mouse models of bone loss

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12 December 2020

Congenital leptin deficiency due to homozygosity for the Delta133G mutation: report of another case and evaluation of response to four years of leptin therapy

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12 December 2020

Osteocalcin and matrix Gla protein: vitamin K-dependent proteins in bone

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12 December 2020

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

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12 December 2020

Central control of bone remodeling by neuromedin U.

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12 December 2020

CREB mediates brain serotonin regulation of bone mass through its expression in ventromedial hypothalamic neurons

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12 December 2020

Identification of a novel extracellular cation-sensing G-protein-coupled receptor

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12 December 2020

Involutional osteoporosis

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12 December 2020

Teleonomic mechanisms in cellular metabolism, growth, and differentiation

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12 December 2020

Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity

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12 December 2020

A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure

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12 December 2020

Leptin regulation of bone resorption by the sympathetic nervous system and CART

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12 December 2020

Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism

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12 December 2020

Leptin and the regulation of body weight in mammals

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12 December 2020

Normal carboxylation of circulating osteocalcin (bone Gla-protein) in Paget's disease of bone

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12 December 2020

Wnt signalling in stem cells and cancer

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12 December 2020

Hematopoietic origin of pathological grooming in Hoxb8 mutant mice

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12 December 2020

Stimulation of Bone Resorption by Parathyroid Hormone in Tissue Culture

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12 December 2020

Discovery and characterization of novel tryptophan hydroxylase inhibitors that selectively inhibit serotonin synthesis in the gastrointestinal tract

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12 December 2020

Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization

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12 December 2020

Leptin-dependent serotonin control of appetite: temporal specificity, transcriptional regulation, and therapeutic implications

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12 December 2020

Interaction between LRP5 and Frat1 mediates the activation of the Wnt canonical pathway.

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12 December 2020

ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae

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12 December 2020

Leptin directly regulates bone cell function in vitro and reduces bone fragility in vivo

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12 December 2020

The osteoblast: a sophisticated fibroblast under central surveillance

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12 December 2020

A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait

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12 December 2020

Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition

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12 December 2020

Dissociation of the neuronal regulation of bone mass and energy metabolism by leptin in vivo

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12 December 2020

Central (ICV) leptin injection increases bone formation, bone mineral density, muscle mass, serum IGF-1, and the expression of osteogenic genes in leptin-deficient ob/ob mice.

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12 December 2020

Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis

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12 December 2020

Bone loss associated with anorexia nervosa

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12 December 2020

The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity

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12 December 2020

Bone and glucose metabolism: a two-way street

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12 December 2020

Osteocyte Wnt/beta-catenin signaling is required for normal bone homeostasis

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12 December 2020

Synthesis of serotonin by a second tryptophan hydroxylase isoform

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12 December 2020

Serum leptin level is a regulator of bone mass

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12 December 2020

Identifiers

DOI

10.1038/NATURE10763

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Dimensions Publication ID

26 August 2017

1053142230

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