(Q37979549)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22285251%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

Intrinsic axonal degeneration pathways are critical for glaucomatous damage (English)

1 reference

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21 January 2020

2

1 reference

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21 January 2020

Richard T. Libby

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22285251%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

author name string

Gareth R Howell

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22285251%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Simon W M John

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22285251%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

language of work or name

English

0 references

publication date

18 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22285251%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

published in

Experimental Neurology

1 reference

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21 January 2020

volume

246

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22285251%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

page(s)

54-61

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22285251%20AND%20SRC:MED&resulttype=core&format=json

Under pressure: cellular and molecular responses during glaucoma, a common neurodegeneration with axonopathy

21 January 2020

cites work

1 reference

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DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activity

6 September 2017

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Datgan, a reusable software system for facile interrogation and visualization of complex transcription profiling data

6 September 2017

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Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma

6 September 2017

1 reference

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The optic nerve head is the site of axonal transport disruption, axonal cytoskeleton damage and putative axonal regeneration failure in a rat model of glaucoma

6 September 2017

1 reference

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Lack of neuroprotection against experimental glaucoma in c-Jun N-terminal kinase 3 knockout mice

6 September 2017

1 reference

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Axonal degeneration is mediated by the mitochondrial permeability transition pore.

6 September 2017

1 reference

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Myelination transition zone astrocytes are constitutively phagocytic and have synuclein dependent reactivity in glaucoma.

6 September 2017

1 reference

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Mitochondrial optic neuropathies - disease mechanisms and therapeutic strategies

6 September 2017

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Functions of astrocytes and their potential as therapeutic targets

6 September 2017

1 reference

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A biomechanical paradigm for axonal insult within the optic nerve head in aging and glaucoma

6 September 2017

1 reference

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Cell proliferation and interleukin-6-type cytokine signaling are implicated by gene expression responses in early optic nerve head injury in rat glaucoma

6 September 2017

1 reference

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Neuroprotection in glaucoma - Is there a future role?

6 September 2017

1 reference

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The role of the classical complement cascade in synapse loss during development and glaucoma

6 September 2017

1 reference

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Microglia in neurodegenerative disease

6 September 2017

1 reference

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Distal axonopathy with structural persistence in glaucomatous neurodegeneration

6 September 2017

1 reference

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A neurotrophic rationale for the therapy of neurodegenerative disorders

6 September 2017

1 reference

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Ocular hypertension impairs optic nerve axonal transport leading to progressive retinal ganglion cell degeneration

6 September 2017

1 reference

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Molecular dissection of reactive astrogliosis and glial scar formation

6 September 2017

1 reference

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Gene expression changes in areas of focal loss of retinal ganglion cells in the retina of DBA/2J mice

6 September 2017

1 reference

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Friend or foe? Resolving the impact of glial responses in glaucoma

6 September 2017

1 reference

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Network analysis of human glaucomatous optic nerve head astrocytes.

6 September 2017

1 reference

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APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

6 September 2017

1 reference

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Mitochondrial dysfunction and glaucoma

6 September 2017

1 reference

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Mouse models of retinal ganglion cell death and glaucoma

6 September 2017

1 reference

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Effect of CNTF on retinal ganglion cell survival in experimental glaucoma

6 September 2017

1 reference

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Mouse genetic models: an ideal system for understanding glaucomatous neurodegeneration and neuroprotection

6 September 2017

1 reference

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Bioinformatic and statistical analysis of the optic nerve head in a primate model of ocular hypertension

6 September 2017

1 reference

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Remodeling of the connective tissue microarchitecture of the lamina cribrosa in early experimental glaucoma

6 September 2017

1 reference

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The WldS gene delays axonal but not somatic degeneration in a rat glaucoma model

6 September 2017

1 reference

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6 September 2017

Nerve injury signaling

1 reference

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Endothelin and its potential role in glaucoma

6 September 2017

1 reference

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Phosphorylation-dependent interaction with 14-3-3 in the regulation of bad trafficking in retinal ganglion cells

6 September 2017

1 reference

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Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma

6 September 2017

1 reference

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Changes in gene expression in experimental glaucoma and optic nerve transection: the equilibrium between protective and detrimental mechanisms

6 September 2017

1 reference

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Rodent models for glaucoma retinopathy and optic neuropathy

6 September 2017

1 reference

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Global changes in optic nerve head gene expression after exposure to elevated intraocular pressure in a rat glaucoma model

6 September 2017

1 reference

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Neuronal death: where does the end begin?

6 September 2017

1 reference

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Vascular matrix adhesion and the blood-brain barrier

6 September 2017

1 reference

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Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric

6 September 2017

1 reference

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Müller cells in the healthy and diseased retina

6 September 2017

1 reference

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Intravitreal injection of endothelin-1 caused optic nerve damage following to ocular hypoperfusion in rabbits

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

The number of people with glaucoma worldwide in 2010 and 2020

6 September 2017

1 reference

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The slow Wallerian degeneration protein, WldS, binds directly to VCP/p97 and partially redistributes it within the nucleus

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

Inherited glaucoma in DBA/2J mice: pertinent disease features for studying the neurodegeneration

6 September 2017

1 reference

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Expression of phosphorylated c-Jun N-terminal protein kinase (JNK) in experimental glaucoma in rats

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

Susceptibility to neurodegeneration in a glaucoma is modified by Bax gene dosage

6 September 2017

1 reference

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Glaucoma: thinking in new ways-a rôle for autonomous axonal self-destruction and other compartmentalised processes?

6 September 2017

1 reference

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Sunday Driver links axonal transport to damage signaling

6 September 2017

1 reference

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The progressive nature of Wallerian degeneration in wild-type and slow Wallerian degeneration (WldS) nerves

6 September 2017

1 reference

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Understanding mechanisms of pressure-induced optic nerve damage

6 September 2017

1 reference

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Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

6 September 2017

1 reference

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The distributions of mitochondria and sodium channels reflect the specific energy requirements and conduction properties of the human optic nerve head

6 September 2017

1 reference

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Cues for apoptotic cell engulfment: eat-me, don't eat-me and come-get-me signals

6 September 2017

1 reference

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Gene therapy with brain-derived neurotrophic factor as a protection: retinal ganglion cells in a rat glaucoma model.

6 September 2017

1 reference

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Morphology of the murine optic nerve.

6 September 2017

1 reference

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Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

Optic nerve head structure in glaucoma: astrocytes as mediators of axonal damage

6 September 2017

1 reference

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Introductory comments on blood flow autoregulation in the optic nerve head and vascular risk factors in glaucoma

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

Number of people with glaucoma worldwide

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

Axoplasmic flow during chronic experimental glaucoma. 1. Light and electron microscopic studies of the monkey optic nervehead during development of glaucomatous cupping

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

Distribution of axonal transport blockade by acute intraocular pressure elevation in the primate optic nerve head

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

Orthograde and retrograde axoplasmic transport during acute ocular hypertension in the monkey

6 September 2017

1 reference

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Failure of increased intracranial pressure to affect rapid axonal transport at the optic nerve head

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

The dynamics and location of axonal transport blockade by acute intraocular pressure elevation in primate optic nerve

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

Blockade of rapid axonal transport. Effect of intraocular pressure elevation in primate optic nerve

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

Structural basis of glaucoma: the fortified astrocytes of the optic nerve head are the target of raised intraocular pressure

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

A dual leucine kinase-dependent axon self-destruction program promotes Wallerian degeneration

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

The effects of elevated intraocular pressure on slow axonal protein flow.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

Selective effects of experimental glaucoma on axonal transport by retinal ganglion cells to the dorsal lateral geniculate nucleus

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

Mitochondria: Their role in ganglion cell death and survival in primary open angle glaucoma

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

Pathogenesis of ganglion "cell death" in glaucoma and neuroprotection: focus on ganglion cell axonal mitochondria

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

Microarray analysis of retinal gene expression in the DBA/2J model of glaucoma

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J mice

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

The pig eye as a novel model of glaucoma

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

A rat model of slow Wallerian degeneration (WldS) with improved preservation of neuromuscular synapses

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

Role of tumor necrosis factor receptor-1 in the death of retinal ganglion cells following optic nerve crush injury in mice

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

Non-apoptotic neurite degeneration in apoptotic neuronal death: pivotal role of mitochondrial function in neurites

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

Neurites can remain viable after destruction of the neuronal soma by programmed cell death (apoptosis).

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

Increase in mitochondrial DNA mutations impairs retinal function and renders the retina vulnerable to injury

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831512

Optic nerve damage in human glaucoma. II. The site of injury and susceptibility to damage

3 December 2018

1 reference

12 December 2020

Absence of Wallerian Degeneration does not Hinder Regeneration in Peripheral Nerve

1 reference

12 December 2020

Rapid axonal transport in primate optic nerve. Distribution of pressure-induced interruption

1 reference

12 December 2020

Regional differences in the structure of the lamina cribrosa and their relation to glaucomatous optic nerve damage

1 reference

12 December 2020

Circulation and axonal transport in the optic nerve

1 reference

12 December 2020

Retrograde axonal transport of JNK signaling molecules influence injury induced nuclear changes in p-c-Jun and ATF3 in adult rat sensory neurons

1 reference

12 December 2020

Chronic experimental glaucoma in primates. I. Production of elevated intraocular pressure by anterior chamber injection of autologous ghost red blood cells

1 reference

12 December 2020

The role of endothelin-1 and its receptors in optic nerve head astrocyte proliferation

1 reference

12 December 2020

Evidence that the Rate of Wallerian Degeneration is Controlled by a Single Autosomal Dominant Gene

1 reference

12 December 2020

Chronic experimental glaucoma in primates. II. Effect of extended intraocular pressure elevation on optic nerve head and axonal transport

1 reference

12 December 2020

Prolonged survival of transected nerve fibres in C57BL/Ola mice is an intrinsic characteristic of the axon

1 reference

12 December 2020

Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma

1 reference

12 December 2020

Endothelin-1 impairs retrograde axonal transport and leads to axonal injury in rat optic nerve

1 reference

12 December 2020

Very Slow Retrograde and Wallerian Degeneration in the CNS of C57BL/Ola Mice

1 reference

12 December 2020

Effect of intraocular pressure on rapid axoplasmic transport in monkey optic nerve

1 reference

12 December 2020

Effect of elevated intraocular pressure on endothelin-1 in a rat model of glaucoma

1 reference

12 December 2020

Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats

1 reference

12 December 2020

Mitochondrial abnormalities in patients with primary open-angle glaucoma

1 reference

12 December 2020

Morphologic changes in the lamina cribrosa correlated with neural loss in open-angle glaucoma

1 reference

12 December 2020

Persistence of neuromuscular junctions after axotomy in mice with slow Wallerian degeneration (C57BL/WldS)

1 reference

12 December 2020

10.1016/J.EXPNEUROL.2012.01.014

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22285251%20AND%20SRC:MED&resulttype=core&format=json

release_rkd4kaub6vhhrcimy3nlf75bqy

21 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rkd4kaub6vhhrcimy3nlf75bqy

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22285251%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference