(Q37301624)

19 August 2017

Mouse genetic models: an ideal system for understanding glaucomatous neurodegeneration and neuroprotection (English)

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ORCID Public Data File 2021

19 August 2017

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author name string

Gareth R Howell

series ordinal

1

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PubMed ID

18929118

19 August 2017

Richard T Libby

series ordinal

2

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PubMed ID

18929118

19 August 2017

Simon W M John

series ordinal

3

1 reference

19 August 2017

1 January 2008

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Progress in Brain Research

19 August 2017

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19 August 2017

173

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19 August 2017

303-321

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Microarray analysis of changes in mRNA levels in the rat retina after experimental elevation of intraocular pressure.

19 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Experimental Mouse Ocular Hypertension: Establishment of the Model

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Evaluation of optineurin sequence variations in 1,048 patients with open-angle glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

High-dose radiation with bone marrow transfer prevents neurodegeneration in an inherited glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Mutations in genes encoding melanosomal proteins cause pigmentary glaucoma in DBA/2J mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Genetic modification of glaucoma associated phenotypes between AKXD-28/Ty and DBA/2J mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Noninvasive assessment of aqueous humor turnover in the mouse eye.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

High occurrence rate of glaucoma among patients with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Erythropoietin--an endogenous retinal survival factor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

The progressive nature of Wallerian degeneration in wild-type and slow Wallerian degeneration (WldS) nerves

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Interacting loci cause severe iris atrophy and glaucoma in DBA/2J mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Neuronal death: where does the end begin?

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

On the use of Tono-Pen XL for the measurement of intraocular pressure in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Quantitative analysis of retinal ganglion cell (RGC) loss in aging DBA/2NNia glaucomatous mice: comparison with RGC loss in aging C57/BL6 mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Optineurin increases cell survival and translocates to the nucleus in a Rab8-dependent manner upon an apoptotic stimulus

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Erythropoietin: novel approaches to neuroprotection in human brain disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Gene mapping for primary open angle glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Mechanisms of optic nerve damage in primary open angle glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Predictability and limitations of non-invasive murine tonometry: comparison of two devices

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Analysis of myocilin mutations in 1703 glaucoma patients from five different populations

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Comparative study of the lamina cribrosa and the pial septa in the vertebrate optic nerve and their relationship to the myelinated axons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Distribution of amyloid precursor protein and amyloid-beta immunoreactivity in DBA/2J glaucomatous mouse retinas

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Prospects for relevant glaucoma models with retinal ganglion cell damage in the rodent eye.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Anterior segment dysgenesis and the developmental glaucomas are complex traits

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Col4a1 mutation causes endoplasmic reticulum stress and genetically modifiable ocular dysgenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Genetically increasing Myoc expression supports a necessary pathologic role of abnormal proteins in glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Mutant myocilin nonsecretion in vivo is not sufficient to cause glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Anterior segment development relevant to glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Laser-induced mouse model of chronic ocular hypertension.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Targeting amyloid-beta in glaucoma treatment.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Distribution of WDR36 DNA sequence variants in patients with primary open-angle glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

The optic nerve head in glaucoma: role of astrocytes in tissue remodeling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Electrophysiological assessment of optic nerve disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Calcineurin cleavage is triggered by elevated intraocular pressure, and calcineurin inhibition blocks retinal ganglion cell death in experimental glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Hsp27 phosphorylation in experimental glaucoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Reactive nonproliferative gliosis predominates in a chronic mouse model of glaucoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Mechanistic insights into glaucoma provided by experimental genetics the cogan lecture

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Demonstration of systematic variation in human intraorbital optic nerve size by quantitative magnetic resonance imaging and histology

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Targeted Disruption of the Myocilin Gene (Myoc) Suggests that Human Glaucoma-Causing Mutations Are Gain of Function

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

The slow Wallerian degeneration protein, WldS, binds directly to VCP/p97 and partially redistributes it within the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Complex genetics of glaucoma susceptibility

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Susceptibility to neurodegeneration in a glaucoma is modified by Bax gene dosage

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Modification of ocular defects in mouse developmental glaucoma models by tyrosinase

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Elevated intraocular pressure and transgenic applications in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Absence of Wallerian Degeneration does not Hinder Regeneration in Peripheral Nerve

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Regional optic nerve damage in experimental mouse glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Studies on copper metabolism. XIV. Copper, ceruloplasmin and oxidase activity in sera of normal human subjects, pregnant women, and patients with infection, hepatolenticular degeneration and the nephrotic syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Causes of optic nerve damage in glaucoma. Robert N. Shaffer lecture

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Optic nerve degeneration in the DBA/2NNia mouse: is the lamina cribrosa important in the development of glaucomatous optic neuropathy?

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Glaucoma: ocular Alzheimer's disease?

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

By altering ocular immune privilege, bone marrow-derived cells pathogenically contribute to DBA/2J pigmentary glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Identification of a novel adult-onset primary open-angle glaucoma (POAG) gene on 5q22.1.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Concentration of astrocytic filaments at the retinal optic nerve junction is coincident with the absence of intra-retinal myelination: comparative and developmental evidence.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Comparison of invasive and non-invasive tonometry in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

IOP-dependent retinal ganglion cell dysfunction in glaucomatous DBA/2J mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Tumor necrosis factor-alpha mediates oligodendrocyte death and delayed retinal ganglion cell loss in a mouse model of glaucoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Noninvasive determination of intraocular pressure (IOP) in nonsedated mice of 5 different inbred strains.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Analysis of porcine optineurin and myocilin expression in trabecular meshwork cells and astrocytes from optic nerve head

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Moving forward with chemical mutagenesis in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Rodent models for glaucoma retinopathy and optic neuropathy

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Electrophysiological analysis of visual function in mutant mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Manometric calibration and comparison of TonoLab and TonoPen tonometers in rats with experimental glaucoma and in normal mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Astrocyte activation and reactive gliosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

The mouse as a model for human biology: a resource guide for complex trait analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Temporal regulation of EphA4 in astroglia during murine retinal and optic nerve development.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Interpretation of the mouse electroretinogram.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

The mouse pattern electroretinogram

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

The pattern electroretinogram as a tool to monitor progressive retinal ganglion cell dysfunction in the DBA/2J mouse model of glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Number of people with glaucoma worldwide

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Regional differences in the structure of the lamina cribrosa and their relation to glaucomatous optic nerve damage

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

The number of people with glaucoma worldwide in 2010 and 2020

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Optic nerve damage in human glaucoma. II. The site of injury and susceptibility to damage

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Blockade of rapid axonal transport. Effect of intraocular pressure elevation in primate optic nerve

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Morphologic changes in the lamina cribrosa correlated with neural loss in open-angle glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Tonopen measurement of intraocular pressure in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Adult-onset primary open-angle glaucoma caused by mutations in optineurin

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Immunolocalization of heat shock proteins in the retina of normal monkey eyes and monkey eyes with laser-induced glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Longitudinal evaluation of retinal ganglion cell function and IOP in the DBA/2J mouse model of glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Optineurin in primary open angle glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Neuroprotective effects and intracellular signaling pathways of erythropoietin in a rat model of multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Intraocular pressure in genetically distinct mice: an update and strain survey

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Expression of mutated mouse myocilin induces open-angle glaucoma in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Glaucoma-causing myocilin mutants require the Peroxisomal targeting signal-1 receptor (PTS1R) to elevate intraocular pressure

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

COL4A1 mutation in Axenfeld-Rieger anomaly with leukoencephalopathy and stroke

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

The mouse anterior chamber angle and trabecular meshwork develop without cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Gene targeting approaches to complex genetic diseases: atherosclerosis and essential hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Ceruloplasmin upregulation in retina of murine and human glaucomatous eyes.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Complement component 1Q (C1Q) upregulation in retina of murine, primate, and human glaucomatous eyes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Microarray analysis of retinal gene expression in the DBA/2J model of glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

The classical complement cascade mediates CNS synapse elimination

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Up-regulation of glial fibrillary acidic protein in the retina of primate eyes with experimental glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Comparison of the lamina cribrosa in mammalian species with good and with indifferent vision

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Immunohistochemical assessment of the glial mitogen-activated protein kinase activation in glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Immunostaining of heat shock proteins in the retina and optic nerve head of normal and glaucomatous eyes.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

The immune system and glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Heat shock proteins, immunity and glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Novel ENU-induced eye mutations in the mouse: models for human eye disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Dominant mutations of Col4a1 result in basement membrane defects which lead to anterior segment dysgenesis and glomerulopathy

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

The relationship between retinal ganglion cell function and retinal nerve fiber thickness in early glaucoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

An immunohistochemical study of neuronal and glial cell reactions in retinae of rats with experimental glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

The importance of models in glaucoma research

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Effect of erythropoietin axotomy-induced apoptosis in rat retinal ganglion cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Prevalence of mutations in TIGR/Myocilin in patients with adult and juvenile primary open-angle glaucoma

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Molecular and clinical evaluation of a patient hemizygous for TIGR/MYOC.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Inhibition of NGF deprivation-induced death by low oxygen involves suppression of BIMEL and activation of HIF-1

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Müller glial cells express nestin coupled with glial fibrillary acidic protein in experimentally induced glaucoma in the rat retina

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Noncancer disease incidence in atomic bomb survivors, 1958-1998.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Neuroprotective effects of erythropoietin on glutamate and nitric oxide toxicity in primary cultured retinal ganglion cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Changes in gene expression in experimental glaucoma and optic nerve transection: the equilibrium between protective and detrimental mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

Erythropoietin promotes survival of retinal ganglion cells in DBA/2J glaucoma mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2808%2901122-9

7 January 2021

10.1016/S0079-6123(08)01122-9

Identifiers

DOI

1 reference

19 August 2017

1 reference

PubMed ID

18929118