(Q36685876)

15 August 2017

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title

The mouse as a model for human biology: a resource guide for complex trait analysis (English)

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15 August 2017

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3

Carol J Bult

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15 August 2017

1

Luanne L Peters

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15 August 2017

5

Beverly J Paigen

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15 August 2017

4

Gary A Churchill

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15 August 2017

6

Karen L Svenson

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15 August 2017

Raymond F Robledo

2

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15 August 2017

1 January 2007

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15 August 2017

Nature Reviews Genetics

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15 August 2017

8

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15 August 2017

58-69

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15 August 2017

1

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https://scigraph.springernature.com/pub.10.1038/nrg2025

15 August 2017

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A collaborative database of inbred mouse strain characteristics.

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A mouse phenome project

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31 March 2020

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Abnormal splicing of the leptin receptor in diabetic mice

31 March 2020

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Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

31 March 2020

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Positional cloning of the mouse obese gene and its human homologue

31 March 2020

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Purkinje cell degeneration associated with erythroid ankyrin deficiency in nb/nb mice

31 March 2020

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Of mice and men: the mice were right

31 March 2020

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440-kD ankyrinB: structure of the major developmentally regulated domain and selective localization in unmyelinated axons

31 March 2020

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nm1054: a spontaneous, recessive, hypochromic, microcytic anemia mutation in the mouse

31 March 2020

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Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells

31 March 2020

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31 March 2020

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31 March 2020

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Mouse ENU mutagenesis

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Recombinant Inbred Lines: Value in the Genetic Analysis of Biochemical Variants

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A new set of BXD recombinant inbred lines from advanced intercross populations in mice

31 March 2020

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Genetic structure of the LXS panel of recombinant inbred mouse strains: a powerful resource for complex trait analysis

31 March 2020

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Strategies for mapping and cloning quantitative trait genes in rodents

31 March 2020

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Genome-wide genetic association of complex traits in heterogeneous stock mice

31 March 2020

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Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains

31 March 2020

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A genome-wide set of congenic mouse strains derived from DBA/2J on a C57BL/6J background

31 March 2020

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Genome-tagged mice (GTM): two sets of genome-wide congenic strains

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Analysing complex genetic traits with chromosome substitution strains

31 March 2020

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Chromosome-wise dissection of the genome of the extremely big mouse line DU6i

31 March 2020

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Chromosome substitution strains: some quantitative considerations for genome scans and fine mapping

31 March 2020

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Germ line integration and Mendelian transmission of the exogenous Moloney leukemia virus

31 March 2020

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Targetted correction of a mutant HPRT gene in mouse embryonic stem cells

31 March 2020

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Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

31 March 2020

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Conditional alleles in mice: practical considerations for tissue-specific knockouts

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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The Ensembl genome database project

31 March 2020

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The UCSC Genome Browser Database: update 2006

31 March 2020

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The UCSC Table Browser data retrieval tool

31 March 2020

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The Mouse Genome Database (MGD): integrating biology with the genome.

31 March 2020

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The Mouse Genome Database (MGD): from genes to mice--a community resource for mouse biology

31 March 2020

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31 March 2020

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The Vertebrate Genome Annotation (Vega) database

31 March 2020

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Mouse Phenome Project: understanding human biology through mouse genetics and genomics

31 March 2020

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Comparative analysis of haplotype association mapping algorithms

31 March 2020

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Use of a dense single nucleotide polymorphism map for in silico mapping in the mouse

31 March 2020

1 reference

Introducing the German Mouse Clinic: open access platform for standardized phenotyping.

31 March 2020

1 reference

Systematic, standardized and comprehensive neurological phenotyping of inbred mice strains in the German Mouse Clinic.

31 March 2020

1 reference

Maps from two interspecific backcross DNA panels available as a community genetic mapping resource

31 March 2020

1 reference

Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse

31 March 2020

1 reference

An efficient SNP system for mouse genome scanning and elucidating strain relationships.

31 March 2020

1 reference

Development of a SNP genotyping panel for genetic monitoring of the laboratory mouse

31 March 2020

1 reference

Insights from human/mouse genome comparisons

31 March 2020

1 reference

Concordance of murine quantitative trait loci for salt-induced hypertension with rat and human loci

31 March 2020

1 reference

Identifying novel genes for atherosclerosis through mouse-human comparative genetics

31 March 2020

1 reference

Unraveling the genetics of chronic kidney disease using animal models

31 March 2020

1 reference

Genetics of variation in HDL cholesterol in humans and mice

31 March 2020

1 reference

Genome-wide search for new genes controlling plasma lipid concentrations in mice and humans

31 March 2020

1 reference

Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility

31 March 2020

1 reference

Complement factor 5 is a quantitative trait gene that modifies liver fibrogenesis in mice and humans

31 March 2020

1 reference

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

31 March 2020

1 reference

From QTL to gene: the harvest begins

31 March 2020

1 reference

The mosaic structure of variation in the laboratory mouse genome

31 March 2020

1 reference

Segmental phylogenetic relationships of inbred mouse strains revealed by fine-scale analysis of sequence variation across 4.6 mb of mouse genome

31 March 2020

1 reference

Genome-wide single-nucleotide polymorphism analysis defines haplotype patterns in mouse

31 March 2020

1 reference

Identification of quantitative trait loci that modify the severity of hereditary spherocytosis in wan, a new mouse model of band-3 deficiency

31 March 2020

1 reference

Genetic modification of hearing in tubby mice: evidence for the existence of a major gene (moth1) which protects tubby mice from hearing loss

31 March 2020

1 reference

Quantitative trait loci for baseline erythroid traits.

31 March 2020

1 reference

Quantitative trait loci for baseline white blood cell count, platelet count, and mean platelet volume.

31 March 2020

1 reference

Association of mean platelet volume with risk of stroke among 3134 individuals with history of cerebrovascular disease

31 March 2020

1 reference

White blood cell count as a predictor of mortality: results over 18 years from the Normative Aging Study

31 March 2020

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Mean platelet volume and myocardial infarction

31 March 2020

1 reference

Influence of platelet size on outcome after myocardial infarction

31 March 2020

1 reference

Prediction of adverse outcomes in children with sickle cell disease

31 March 2020

1 reference

The acute chest syndrome of sickle cell disease

31 March 2020

1 reference

Mortality in sickle cell disease. Life expectancy and risk factors for early death.

31 March 2020

1 reference

Pain in sickle cell disease. Rates and risk factors

31 March 2020

1 reference

A simple method to calculate resolving power and confidence interval of QTL map location

31 March 2020

1 reference

Conserved synteny in rat and mouse for a blood pressure QTL on human chromosome 17

31 March 2020

1 reference

Identification of candidate disease genes by EST alignments, synteny, and expression and verification of Ensembl genes on rat chromosome 1q43-54.

31 March 2020

1 reference

Interspecies synteny mapping identifies a quantitative trait locus for bone mineral density on human chromosome Xp22

31 March 2020

1 reference

Combining data from multiple inbred line crosses improves the power and resolution of quantitative trait loci mapping

31 March 2020

1 reference

Genetic analysis of blood pressure in C3H/HeJ and SWR/J mice

31 March 2020

1 reference

Quantitative trait loci that determine BMD in C57BL/6J and 129S1/SvImJ inbred mice

31 March 2020

1 reference

Haplotype analysis in multiple crosses to identify a QTL gene

31 March 2020

1 reference

Platelet formation is the consequence of caspase activation within megakaryocytes

31 March 2020

1 reference

The birth of the platelet

31 March 2020

1 reference

Megakaryocytes and beyond: the birth of platelets

31 March 2020

1 reference

A role for Rab27b in NF-E2-dependent pathways of platelet formation

31 March 2020

1 reference

Review of microarray experimental design strategies for genetical genomics studies

31 March 2020

1 reference

Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes.

31 March 2020

1 reference

Cis-acting expression quantitative trait loci in mice

31 March 2020

1 reference

Integrating genetic and gene expression data: application to cardiovascular and metabolic traits in mice

31 March 2020

1 reference

Identification of candidate genes in the type 2 diabetes modifier locus using expression QTL

31 March 2020

1 reference

Simulating the collaborative cross: power of quantitative trait loci detection and mapping resolution in large sets of recombinant inbred strains of mice

31 March 2020

1 reference

The Collaborative Cross, a community resource for the genetic analysis of complex traits

31 March 2020

1 reference

In silico mapping of complex disease-related traits in mice.

31 March 2020

1 reference

In silico quantitative trait locus map for atherosclerosis susceptibility in apolipoprotein E-deficient mice

31 March 2020

1 reference

Structural model analysis of multiple quantitative traits

31 March 2020

1 reference

Using advanced intercross lines for high-resolution mapping of HDL cholesterol quantitative trait loci

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRG2025

1 reference

15 August 2017

1 reference

PubMed ID

17173058