(Q37979739)

26 August 2017

Balancing self-renewal and differentiation by asymmetric division: insights from brain tumor suppressors in Drosophila neural stem cells (English)

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26 August 2017

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Kai Chen Chang

1

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26 August 2017

Cheng Wang

series ordinal

2

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26 August 2017

Hongyan Wang

series ordinal

3

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26 August 2017

language of work or name

English

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publication date

27 January 2012

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26 August 2017

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26 August 2017

34

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26 August 2017

4

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26 August 2017

301-310

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Brainy but not too brainy: starting and stopping neuroblast divisions in Drosophila.

26 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Proliferation pattern of postembryonic neuroblasts in the brain of Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

The PAR-aPKC system: lessons in polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

The PAR proteins: fundamental players in animal cell polarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Cdc42 acts downstream of Bazooka to regulate neuroblast polarity through Par-6 aPKC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Locomotion defects, together with Pins, regulates heterotrimeric G-protein signaling during Drosophila neuroblast asymmetric divisions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Differential functions of G protein and Baz-aPKC signaling pathways in Drosophila neuroblast asymmetric division.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Role of inscuteable in orienting asymmetric cell divisions in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Asymmetric segregation of Numb and Prospero during cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Staufen-dependent localization of prospero mRNA contributes to neuroblast daughter-cell fate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

The prospero gene specifies cell fates in the drosophila central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

prospero is expressed in neuronal precursors and encodes a nuclear protein that is involved in the control of axonal outgrowth in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Miranda directs Prospero to a daughter cell during Drosophila asymmetric divisions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Miranda is required for the asymmetric localization of Prospero during mitosis in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Identification of Miranda protein domains regulating asymmetric cortical localization, cargo binding, and cortical release

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Partner of Numb colocalizes with Numb during mitosis and directs Numb asymmetric localization in Drosophila neural and muscle progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Modes of protein movement that lead to the asymmetric localization of partner of Numb during Drosophila neuroblast division

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

aPKC phosphorylates Miranda to polarize fate determinants during neuroblast asymmetric cell division.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Stem cells, cancer, and cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Lgl, Pins and aPKC regulate neuroblast self-renewal versus differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Metastatic ability of Drosophila tumors depends on MMP activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Prospero acts as a binary switch between self-renewal and differentiation in Drosophila neural stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Drosophila brain tumor metastases express both neuronal and glial cell type markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Drosophila aPKC regulates cell polarity and cell proliferation in neuroblasts and epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Dap160/intersectin binds and activates aPKC to regulate cell polarity and cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Protein phosphatase 2A regulates self-renewal of Drosophila neural stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Interplay between the transcription factor Zif and aPKC regulates neuroblast polarity and self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

At the crossroads of polarity, proliferation and apoptosis: the use of Drosophila to unravel the multifaceted role of endocytosis in tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Apical-basal polarity in Drosophila neuroblasts is independent of vesicular trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Endocytosis and intracellular trafficking of Notch and its ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Amplification of neural stem cell proliferation by intermediate progenitor cells in Drosophila brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Identification of Drosophila type II neuroblast lineages containing transit amplifying ganglion mother cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

dFezf/Earmuff maintains the restricted developmental potential of intermediate neural progenitors in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

The bHLH factor deadpan is a direct target of Notch signaling and regulates neuroblast self-renewal in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Regulation of cell growth by Notch signaling and its differential requirement in normal vs. tumor-forming stem cells in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Centrosome dysfunction in Drosophila neural stem cells causes tumors that are not due to genome instability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

PP2A antagonizes phosphorylation of Bazooka by PAR-1 to control apical-basal polarity in dividing embryonic neuroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Twins/PP2A regulates aPKC to control neuroblast cell polarity and self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Protein phosphatase 2A negatively regulates aPKC signaling by modulating phosphorylation of Par-6 in Drosophila neuroblast asymmetric divisions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Dronc caspase exerts a non-apoptotic function to restrain phospho-Numb-induced ectopic neuroblast formation in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Protein phosphatase 4 mediates localization of the Miranda complex during Drosophila neuroblast asymmetric divisions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Ric-8 controls Drosophila neural progenitor asymmetric division by regulating heterotrimeric G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Drosophila Ric-8 regulates Galphai cortical localization to promote Galphai-dependent planar orientation of the mitotic spindle during asymmetric cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

The Drosophila NuMA Homolog Mud regulates spindle orientation in asymmetric cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Drosophila Pins-binding protein Mud regulates spindle-polarity coupling and centrosome organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Progenitor properties of symmetrically dividing Drosophila neuroblasts during embryonic and larval development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Apical/basal spindle orientation is required for neuroblast homeostasis and neuronal differentiation in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Huntingtin is required for mitotic spindle orientation and mammalian neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Microtubule-induced Pins/Galphai cortical polarity in Drosophila neuroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Identification of an Aurora-A/PinsLINKER/Dlg spindle orientation pathway using induced cell polarity in S2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Functionally unequal centrosomes drive spindle orientation in asymmetrically dividing Drosophila neural stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

A role for a novel centrosome cycle in asymmetric cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Drosophila neuroblasts retain the daughter centrosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Cnn dynamics drive centrosome size asymmetry to ensure daughter centriole retention in Drosophila neuroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

An ana2/ctp/mud complex regulates spindle orientation in Drosophila neuroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

21 January 2018

Flies without centrioles

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

The PDZ protein Canoe regulates the asymmetric division of Drosophila neuroblasts and muscle progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Canoe binds RanGTP to promote Pins(TPR)/Mud-mediated spindle orientation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

The Rap1-Rgl-Ral signaling network regulates neuroblast cortical polarity and spindle orientation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Expression of the stem cell self-renewal gene Hiwi and risk of tumour-related death in patients with soft-tissue sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

The stem cell-associated Hiwi gene in human adenocarcinoma of the pancreas: expression and risk of tumour-related death

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

The E-cadherin-repressed hNanos1 gene induces tumor cell invasion by upregulating MT1-MMP expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Ectopic expression of germline genes drives malignant brain tumor growth in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Epigenetic licensing of germline gene expression by maternal RNA in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Regulation of spindle orientation and neural stem cell fate in the Drosophila optic lobe

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Coordinated sequential action of EGFR and Notch signaling pathways regulates proneural wave progression in the Drosophila optic lobe.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Regulation of imaginal disc growth by tumor-suppressor genes in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

Influence of fat-hippo and notch signaling on the proliferation and differentiation of Drosophila optic neuroepithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

The tumour suppressor L(3)mbt inhibits neuroepithelial proliferation and acts on insulator elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100090

21 January 2018

Identifiers

DOI

10.1002/BIES.201100090

1 reference

release_fh4x6hsmcfeu5odfcr5nwom7lu

26 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fh4x6hsmcfeu5odfcr5nwom7lu

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference