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Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon.
scientific article
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scholarly article
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stated in
Europe PubMed Central
PMC publication ID
3047501
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17805297%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
title
Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3047501
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17805297%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
main subject
phosphorylation
0 references
Polo Dmel_CG12306
1 reference
stated in
GOA release 2020-03-11
author
Hongyan Wang
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3047501
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17805297%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
author name string
Yingshi Ouyang
series ordinal
2
1 reference
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Europe PubMed Central
PMC publication ID
3047501
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17805297%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
W Gregory Somers
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3047501
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17805297%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
William Chia
series ordinal
4
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Europe PubMed Central
PMC publication ID
3047501
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17805297%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
Bingwei Lu
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
3047501
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17805297%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
language of work or name
English
0 references
publication date
1 September 2007
1 reference
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Europe PubMed Central
PMC publication ID
3047501
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17805297%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
published in
Nature
1 reference
stated in
Europe PubMed Central
PMC publication ID
3047501
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17805297%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
volume
449
1 reference
stated in
Europe PubMed Central
PMC publication ID
3047501
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17805297%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
issue
7158
1 reference
stated in
Europe PubMed Central
PMC publication ID
3047501
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17805297%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
page(s)
96-100
1 reference
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Europe PubMed Central
PMC publication ID
3047501
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17805297%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/nature06056
0 references
cites work
aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
7 July 2018
Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
7 July 2018
Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
7 July 2018
Prospero acts as a binary switch between self-renewal and differentiation in Drosophila neural stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
7 July 2018
Asymmetric and symmetric stem-cell divisions in development and cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
7 July 2018
Drosophila Pins-binding protein Mud regulates spindle-polarity coupling and centrosome organization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
7 July 2018
The NuMA-related Mud protein binds Pins and regulates spindle orientation in Drosophila neuroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
7 July 2018
Polo-like kinases: a team in control of the division
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
7 July 2018
Aberrant activation of notch signaling in human breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
7 July 2018
Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
7 July 2018
Polo-like kinases and the orchestration of cell division
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
7 July 2018
Asymmetric cell division in the Drosophila nervous system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
7 July 2018
Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
7 July 2018
Modes of protein movement that lead to the asymmetric localization of partner of Numb during Drosophila neuroblast division
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
7 July 2018
In vivo localisation of the mitotic POLO kinase shows a highly dynamic association with the mitotic apparatus during early embryogenesis in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
7 July 2018
Partner of Numb colocalizes with Numb during mitosis and directs Numb asymmetric localization in Drosophila neural and muscle progenitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
7 July 2018
Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
7 July 2018
polo, a mitotic mutant of Drosophila displaying abnormal spindle poles.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
7 July 2018
The mammalian Golgi regulates numb signaling in asymmetric cell division by releasing ACBD3 during mitosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
26 October 2018
The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
26 October 2018
Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
26 October 2018
Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
26 October 2018
Lgl, Pins and aPKC regulate neuroblast self-renewal versus differentiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
26 October 2018
Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
26 October 2018
Localization-dependent and -independent roles of numb contribute to cell-fate specification in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
26 October 2018
POLO kinase regulates the Drosophila centromere cohesion protein MEI-S332.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
26 October 2018
PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
26 October 2018
Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
26 October 2018
cdc2 links the Drosophila cell cycle and asymmetric division machineries
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
26 October 2018
Asymmetric segregation of Numb and Prospero during cell division
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3047501
retrieved
26 October 2018
Identifiers
DOI
10.1038/NATURE06056
1 reference
stated in
Europe PubMed Central
PMC publication ID
3047501
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17805297%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
Dimensions Publication ID
1010301032
0 references
PMC publication ID
3047501
1 reference
stated in
Europe PubMed Central
PMC publication ID
3047501
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17805297%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
PubMed ID
17805297
1 reference
stated in
Europe PubMed Central
PMC publication ID
3047501
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17805297%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
ResearchGate publication ID
6035784
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