(Q37984124)

26 August 2017

title

Curcumin molecular targets in obesity and obesity-related cancers (English)

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26 August 2017

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Adeeb Shehzad

1

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26 August 2017

Salman Khan

series ordinal

2

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26 August 2017

Young Sup Lee

series ordinal

3

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26 August 2017

language of work or name

English

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publication date

1 February 2012

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26 August 2017

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26 August 2017

volume

8

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26 August 2017

issue

2

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26 August 2017

page(s)

179-190

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Obesity wars: molecular progress confronts an expanding epidemic

26 August 2017

cites work

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Obesity in C57BL/6J mice is characterized by adipose tissue hypoxia and cytotoxic T-cell infiltration.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Obesity and cancer risk: the role of the insulin-IGF axis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcumin eliminates leptin's effects on hepatic stellate cell activation via interrupting leptin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Insulin and insulin-like growth factor signalling in neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Reduced susceptibility to two-stage skin carcinogenesis in mice with low circulating insulin-like growth factor I levels

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Insulin-like growth factor 1 (IGF1), IGF binding protein 3 (IGFBP3), and breast cancer risk: pooled individual data analysis of 17 prospective studies

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Non-alcoholic fatty liver disease progresses to hepatocellular carcinoma in the absence of apparent cirrhosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Quantitative FRET imaging of leptin receptor oligomerization kinetics in single cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Adiponectin differentially affects gene expression in human mammary epithelial and breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis.

21 January 2018

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https://api.crossref.org/works/10.2217%2FFON.11.145

Adiponectin as a negative regulator in obesity-related mammary carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Adipocytokines: mediators linking adipose tissue, inflammation and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Adiposity and sex hormones in postmenopausal breast cancer survivors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Identification of molecular targets for dietary energy restriction prevention of skin carcinogenesis: an idea cultivated by Edward Bresnick

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Comparative antioxidant activities of curcumin and its demethoxy and hydrogenated derivatives.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

The potentiation of curcumin on insulin-like growth factor-1 action in MCF-7 human breast carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcumin upregulates insulin-like growth factor binding protein-5 (IGFBP-5) and C/EBPalpha during oral cancer suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Insulin-like growth factors are more effective than progastrin in reversing proapoptotic effects of curcumin: critical role of p38MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcumin and resveratrol inhibit nuclear factor-kappaB-mediated cytokine expression in adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Cytokines suppress adipogenesis and PPAR-gamma function through the TAK1/TAB1/NIK cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Inhibitory effect of curcumin on uterine leiomyoma cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Suppression of fatty acid synthase, differentiation and lipid accumulation in adipocytes by curcumin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Leptin and gastro-intestinal malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcumin protects hepatic stellate cells against leptin-induced activation in vitro by accumulating intracellular lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcumin prevents leptin raising glucose levels in hepatic stellate cells by blocking translocation of glucose transporter-4 and increasing glucokinase

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Targeting inflammation-induced obesity and metabolic diseases by curcumin and other nutraceuticals

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Adiponectin: more than just another fat cell hormone?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Induction of adiponectin by natural and synthetic phenolamides in mouse and human preadipocytes and its enhancement by docosahexaenoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activities

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Effects of curcumin on secretion of adiponectin and interleukin-6 in human adipose tissues: an in vitro study

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Biological mechanisms linking obesity and cancer risk: new perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcumin decreases cholangiocarcinogenesis in hamsters by suppressing inflammation-mediated molecular events related to multistep carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Active spice-derived components can inhibit inflammatory responses of adipose tissue in obesity by suppressing inflammatory actions of macrophages and release of monocyte chemoattractant protein-1 from adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcumin diminishes the impacts of hyperglycemia on the activation of hepatic stellate cells by suppressing membrane translocation and gene expression of glucose transporter-2

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcumin suppresses the expression of extracellular matrix genes in activated hepatic stellate cells by inhibiting gene expression of connective tissue growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcumin-induced suppression of adipogenic differentiation is accompanied by activation of Wnt/beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcumin supplementation lowers TNF-alpha, IL-6, IL-8, and MCP-1 secretion in high glucose-treated cultured monocytes and blood levels of TNF-alpha, IL-6, MCP-1, glucose, and glycosylated hemoglobin in diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcumin inhibits adipogenesis in 3T3-L1 adipocytes and angiogenesis and obesity in C57/BL mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

The metabolic syndrome: A high-risk state for cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcumin adds spice to the debate: lipid metabolism in liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

The antihyperglycemic effect of curcumin in high fat diet fed rats. Role of TNF-α and free fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Hypocholesterolemic effects of curcumin via up-regulation of cholesterol 7a-hydroxylase in rats fed a high fat diet

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcumin induces changes in expression of genes involved in cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Beneficial effects of curcumin on hyperlipidemia and insulin resistance in high-fat-fed hamsters

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Protective effect of dietary curcumin and capsaicin on induced oxidation of low-density lipoprotein, iron-induced hepatotoxicity and carrageenan-induced inflammation in experimental rats

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Redox modulation and human bile duct cancer inhibition by curcumin.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcumin exerts multiple suppressive effects on human breast carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcumin counteracts the proliferative effect of estradiol and induces apoptosis in cervical cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcumin blocks the activation of androgen and interlukin-6 on prostate-specific antigen expression in human prostatic carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Epigenetic regulation of high glucose-induced proinflammatory cytokine production in monocytes by curcumin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Dose escalation of a curcuminoid formulation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Phase I clinical trial of oral curcumin: biomarkers of systemic activity and compliance

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcumin in cancer chemoprevention: molecular targets, pharmacokinetics, bioavailability, and clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcumin effects on blood lipid profile in a 6-month human study

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Mitochondrial and nuclear DNA damage induced by curcumin in human hepatoma G2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

Curcuminoids inhibit multiple human cytochromes P450, UDP-glucuronosyltransferase, and sulfotransferase enzymes, whereas piperine is a relatively selective CYP3A4 inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.11.145

21 January 2018

Identifiers

DOI

10.2217/FON.11.145

1 reference

26 August 2017

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