(Q24647242)

English

Curcuminoids inhibit multiple human cytochromes P450, UDP-glucuronosyltransferase, and sulfotransferase enzymes, whereas piperine is a relatively selective CYP3A4 inhibitor

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scholarly article

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Curcuminoids inhibit multiple human cytochromes P450, UDP-glucuronosyltransferase, and sulfotransferase enzymes, whereas piperine is a relatively selective CYP3A4 inhibitor (English)

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Michael H Court

4

object named as

Michael H Court

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author name string

Laurie P Volak

1

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Senait Ghirmai

2

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John R Cashman

3

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language of work or name

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publication date

August 2008

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Drug Metabolism and Disposition

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36

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8

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1594-605

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1 reference

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The human intestinal cytochrome P450 "pie".

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574793

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Biochemical basis of enhanced drug bioavailability by piperine: evidence that piperine is a potent inhibitor of drug metabolism

1 reference

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1 reference

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27 September 2017

In vitro and in vivo inhibition of pulmonary cytochrome P450 activities by piperine, a major ingredient of piper species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574793

30 May 2018

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1 reference

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30 May 2018

The development of a cocktail CYP2B6, CYP2C8, and CYP3A5 inhibition assay and a preliminary assessment of utility in a drug discovery setting.

1 reference

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28 November 2018

Curcumin maintenance therapy for ulcerative colitis: randomized, multicenter, double-blind, placebo-controlled trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574793

28 November 2018

Impact of curcumin-induced changes in P-glycoprotein and CYP3A expression on the pharmacokinetics of peroral celiprolol and midazolam in rats.

1 reference

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Combination treatment with curcumin and quercetin of adenomas in familial adenomatous polyposis.

1 reference

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1 reference

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1 reference

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Photophysical studies on binding of curcumin to bovine serum albumins

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1 reference

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18480186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alprazolam metabolism in vitro: studies of human, monkey, mouse, and rat liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18480186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18480186

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1124/DMD.108.020552

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