(Q37986126)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22348352%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

The placenta, transfer of immunoglobulins, and safety assessment of biopharmaceuticals in pregnancy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22348352%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

4

1 reference

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23 January 2020

author name string

John M DeSesso

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22348352%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Amy L Williams

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22348352%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Arshiya Ahuja

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22348352%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Mark E Hurtt

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22348352%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

language of work or name

English

0 references

publication date

1 March 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22348352%20AND%20SRC:MED&resulttype=core&format=json

Critical Reviews in Toxicology

23 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22348352%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

volume

42

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22348352%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22348352%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

page(s)

185-210

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22348352%20AND%20SRC:MED&resulttype=core&format=json

The versatile MHC class I-related FcRn protects IgG and albumin from degradation: implications for development of new diagnostics and therapeutics.

23 January 2020

cites work

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Cross-species binding analyses of mouse and human neonatal Fc receptor show dramatic differences in immunoglobulin G and albumin binding

21 January 2018

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Expression of functionally active FcRn and the differentiated bidirectional transport of IgG in human placental endothelial cells

21 January 2018

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Multidrug resistance gene expression is controlled by steroid hormones in the secretory epithelium of the uterus

21 January 2018

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Immune and non-immune functions of the (not so) neonatal Fc receptor, FcRn.

21 January 2018

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Strategies and challenges for the next generation of therapeutic antibodies

21 January 2018

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Comparative placental morphology and function

21 January 2018

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Lysosomal Enzyme Inhibition by Trypan Blue: A Theory of Teratogenesis

21 January 2018

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Embryo-fetal developmental toxicity of figitumumab, an anti-insulin-like growth factor-1 receptor (IGF-1R) monoclonal antibody, in cynomolgus monkeys.

21 January 2018

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Cytotrophoblast cells: a barrier to maternofetal transmission of passive immunity.

21 January 2018

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Nutrition of the human fetus during the first trimester--a review

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Mechanisms regulating toxicant disposition to the embryo during early pregnancy: an interspecies comparison

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Trophoblast-uterine interactions in the first days of implantation: models for the study of implantation events in the human

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Differentiation of the embryonic disc, amnion, and yolk sac in the rhesus monkey

21 January 2018

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The MHC class I-related receptor, FcRn, plays an essential role in the maternofetal transfer of gamma-globulin in humans

21 January 2018

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FcRn: the MHC class I-related receptor that is more than an IgG transporter

21 January 2018

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THE SELECTIVITY OF THE HUMAN PLACENTA IN THE TRANSFER OF PLASMA PROTEINS FROM MOTHER TO FETUS.

21 January 2018

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21 January 2018

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Protection of newborn mice against herpes simplex virus infection by prenatal and postnatal transmission of antibody

21 January 2018

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Mode of action: yolk sac poisoning and impeded histiotrophic nutrition--HBOC-related congenital malformations

21 January 2018

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Development, morphology, and function of the yolk-sac placenta of laboratory rodents

21 January 2018

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Drug biotransformation in the placenta

21 January 2018

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Placental transport of immunoglobulins: a clinical review for gastroenterologists who prescribe therapeutic monoclonal antibodies to women during conception and pregnancy

21 January 2018

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FcRn in the yolk sac endoderm of mouse is required for IgG transport to fetus

21 January 2018

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The Fc receptor for IgG expressed in the villus endothelium of human placenta is Fc gamma RIIb2.

21 January 2018

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Placental structure: in a comparative aspect

21 January 2018

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A comparison of placental development and endocrine functions between the human and mouse model

21 January 2018

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Ex vivo human placenta models: transport of immunoglobulin G and its subclasses

21 January 2018

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Developmental toxicity testing of biopharmaceuticals in nonhuman primates: previous experience and future directions

21 January 2018

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Considerations in assessing the developmental and reproductive toxicity potential of biopharmaceuticals

21 January 2018

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Maturation of the maternofoetal transport system for human gamma-globulin in the mouse

21 January 2018

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21 January 2018

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Differences in promiscuity for antibody-FcRn interactions across species: implications for therapeutic antibodies

21 January 2018

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An interspecies comparison of placental antibody transfer: new insights into developmental toxicity testing of monoclonal antibodies

21 January 2018

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The role of the placenta in fetal exposure to xenobiotics: importance of membrane transporters and human models for transfer studies.

21 January 2018

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Selective disruption of lymphotoxin ligands reveals a novel set of mucosal lymph nodes and unique effects on lymph node cellular organization.

21 January 2018

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Isolation and characterization of the Fc receptor from the fetal yolk sac of the rat

21 January 2018

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21 January 2018

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A variable number of tandem repeats polymorphism influences the transcriptional activity of the neonatal Fc receptor alpha-chain promoter.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Morphometric evaluation of the microvillous surface enlargement factor in the human placenta from mid-gestation to term.

21 January 2018

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Divergent activities of an engineered antibody in murine and human systems have implications for therapeutic antibodies

21 January 2018

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Soluble endoglin contributes to the pathogenesis of preeclampsia

21 January 2018

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The use of surrogate antibodies to evaluate the developmental and reproductive toxicity potential of an anti-TNFalpha PEGylated Fab' monoclonal antibody.

21 January 2018

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Effects of natalizumab, an alpha4 integrin inhibitor, on fertility in male and female guinea pigs

21 January 2018

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Angiogenesis during primate placentation in health and disease

21 January 2018

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Translational pharmacokinetics and pharmacodynamics of an FcRn-variant anti-CD4 monoclonal antibody from preclinical model to phase I study

21 January 2018

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