(Q37994016)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22421512%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Podocytes: gaining a foothold (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22421512%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22421512%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

author name string

Lawrence B Holzman

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22421512%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

language of work or name

English

0 references

publication date

7 March 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22421512%20AND%20SRC:MED&resulttype=core&format=json

Experimental Cell Research

26 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22421512%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

318

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22421512%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22421512%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

955-963

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22421512%20AND%20SRC:MED&resulttype=core&format=json

The tight junction protein ZO-1 is concentrated along slit diaphragms of the glomerular epithelium

26 January 2020

cites work

1 reference

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An essential role of the universal polarity protein, aPKClambda, on the maintenance of podocyte slit diaphragms

7 January 2021

1 reference

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Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome

7 January 2021

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The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

7 January 2021

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Regulation of cell polarity during epithelial morphogenesis

7 January 2021

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Prenatal diagnosis of congenital nephrotic syndrome (CNF, NPHS1).

7 January 2021

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Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN

7 January 2021

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Preferential adhesion mediated by Hibris and Roughest regulates morphogenesis and patterning in the Drosophila eye.

7 January 2021

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Synaptic specificity is generated by the synaptic guidepost protein SYG-2 and its receptor, SYG-1.

7 January 2021

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The immunoglobulin superfamily protein SYG-1 determines the location of specific synapses in C. elegans

7 January 2021

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Functional dissection of SYG-1 and SYG-2, cell adhesion molecules required for selective synaptogenesis in C. elegans

7 January 2021

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Nephrin and Neph1 co-localize at the podocyte foot process intercellular junction and form cis hetero-oligomers

7 January 2021

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Bidirectional modulation of synaptic functions by Eph/ephrin signaling.

7 January 2021

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Eph/ephrin molecules--a hub for signaling and endocytosis

7 January 2021

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A role of receptor Notch in ligand cis-inhibition in Drosophila.

7 January 2021

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cis-Inhibition of Notch by endogenous Delta biases the outcome of lateral inhibition.

7 January 2021

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Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization

7 January 2021

1 reference

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Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization

7 January 2021

1 reference

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Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes

7 January 2021

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Actin-depolymerizing factor cofilin-1 is necessary in maintaining mature podocyte architecture

7 January 2021

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Fyn binds to and phosphorylates the kidney slit diaphragm component Nephrin

7 January 2021

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Clustering-induced tyrosine phosphorylation of nephrin by Src family kinases

7 January 2021

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SRC-family kinase Fyn phosphorylates the cytoplasmic domain of nephrin and modulates its interaction with podocin

7 January 2021

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Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome

7 January 2021

1 reference

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Phosphorylation of nephrin triggers its internalization by raft-mediated endocytosis

7 January 2021

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Actin-based motility of vaccinia virus mimics receptor tyrosine kinase signalling.

7 January 2021

1 reference

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Grb2 and Nck act cooperatively to promote actin-based motility of vaccinia virus

7 January 2021

1 reference

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Nck-independent actin assembly is mediated by two phosphorylated tyrosines within enteropathogenic Escherichia coli Tir.

7 January 2021

1 reference

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c-mip impairs podocyte proximal signaling and induces heavy proteinuria

7 January 2021

1 reference

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Phosphorylated YDXV motifs and Nck SH2/SH3 adaptors act cooperatively to induce actin reorganization

7 January 2021

1 reference

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A risk allele for focal segmental glomerulosclerosis in African Americans is located within a region containing APOL1 and MYH9

7 January 2021

1 reference

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MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis

7 January 2021

1 reference

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Podocyte-specific deletion of Myh9 encoding nonmuscle myosin heavy chain 2A predisposes mice to glomerulopathy.

7 January 2021

1 reference

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Association of trypanolytic ApoL1 variants with kidney disease in African Americans

7 January 2021

1 reference

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Motor protein Myo1c is a podocyte protein that facilitates the transport of slit diaphragm protein Neph1 to the podocyte membrane

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

MYO1E mutations and childhood familial focal segmental glomerulosclerosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Disruption of Myosin 1e promotes podocyte injury

7 January 2021

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Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity

7 January 2021

1 reference

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Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus

7 January 2021

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Integrin-linked kinase (ILK): a regulator of integrin and growth-factor signalling.

7 January 2021

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Podocyte-specific deletion of integrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis.

7 January 2021

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Interaction of focal adhesion kinase with cytoskeletal protein talin

7 January 2021

1 reference

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Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2.

7 January 2021

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Tyrosine phosphorylation of paxillin, FAK, and p130CAS: effects on cell spreading and migration

7 January 2021

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Focal adhesion kinase: a prominent determinant in breast cancer initiation, progression and metastasis

7 January 2021

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Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells

7 January 2021

1 reference

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Inhibition of podocyte FAK protects against proteinuria and foot process effacement.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Glomerular structure and function require paracrine, not autocrine, VEGF-VEGFR-2 signaling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases

7 January 2021

1 reference

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VEGF inhibition and renal thrombotic microangiopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Circulating angiogenic factors and the risk of preeclampsia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Placental ischemia and soluble fms-like tyrosine kinase 1: cause or consequence of preeclampsia?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Parietal epithelial cells: their role in health and disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Glomerular epithelial stem cells: the good, the bad, and the ugly.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Podocyte injury damages other podocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Podocyte hypertrophy, "adaptation," and "decompensation" associated with glomerular enlargement and glomerulosclerosis in the aging rat: prevention by calorie restriction.

7 January 2021

1 reference

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The spectrum of podocytopathies: a unifying view of glomerular diseases.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Dynamics of the Rho-family small GTPases in actin regulation and motility

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Rho GTPases and the actin cytoskeleton

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Synaptopodin orchestrates actin organization and cell motility via regulation of RhoA signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidney disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Progressive impairment of kidneys and reproductive organs in mice lacking Rho GDIalpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

The expanding TOR signaling network

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Complexity of the TOR signaling network

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

The regulation of aging: does autophagy underlie longevity?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Development by self-digestion: molecular mechanisms and biological functions of autophagy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Implications of autophagy for glomerular aging and disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030

Spatial coupling of mTOR and autophagy augments secretory phenotypes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.02.030