(Q37994954)

PubMed publication ID

22430017

26 August 2017

title

Optogenetic investigation of neural circuits underlying brain disease in animal models (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6682316&resulttype=core&format=json

11 May 2020

1 reference

2

Karl Deisseroth

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6682316&resulttype=core&format=json

11 May 2020

author name string

Kay M Tye

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6682316&resulttype=core&format=json

11 May 2020

language of work or name

English

0 references

publication date

20 March 2012

1 reference

PubMed publication ID

22430017

Nature Reviews Neuroscience

26 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6682316&resulttype=core&format=json

11 May 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6682316&resulttype=core&format=json

11 May 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6682316&resulttype=core&format=json

11 May 2020

page(s)

251-266

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6682316&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrn3171

11 May 2020

exact match

0 references

1 reference

Next-generation optical technologies for illuminating genetically targeted brain circuits

31 March 2020

1 reference

The microbial opsin family of optogenetic tools

31 March 2020

1 reference

Temporally precise in vivo control of intracellular signalling

31 March 2020

1 reference

Millisecond-timescale, genetically targeted optical control of neural activity

31 March 2020

1 reference

Optogenetics in neural systems

31 March 2020

1 reference

The development and application of optogenetics

31 March 2020

1 reference

Optogenetic investigation of neural circuits in vivo

31 March 2020

1 reference

An optical neural interface: in vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology

31 March 2020

1 reference

Optogenetic manipulation of neural circuitry in vivo.

31 March 2020

1 reference

Remote control of behavior through genetically targeted photostimulation of neurons

31 March 2020

1 reference

Channelrhodopsin-1: a light-gated proton channel in green algae.

31 March 2020

1 reference

Channelrhodopsin-2, a directly light-gated cation-selective membrane channel

31 March 2020

1 reference

Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri

31 March 2020

1 reference

High-efficiency channelrhodopsins for fast neuronal stimulation at low light levels

31 March 2020

1 reference

Molecular and cellular approaches for diversifying and extending optogenetics

31 March 2020

1 reference

Bi-stable neural state switches

31 March 2020

1 reference

Multimodal fast optical interrogation of neural circuitry

31 March 2020

1 reference

High-performance genetically targetable optical neural silencing by light-driven proton pumps

31 March 2020

1 reference

Ultrafast optogenetic control.

31 March 2020

1 reference

Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsins

31 March 2020

1 reference

A simple head-mountable LED device for chronic stimulation of optogenetic molecules in freely moving mice

31 March 2020

1 reference

Controlling neuronal activity

31 March 2020

1 reference

An optogenetic toolbox designed for primates

31 March 2020

1 reference

Neural substrates of awakening probed with optogenetic control of hypocretin neurons

31 March 2020

1 reference

Multi-site optical excitation using ChR2 and micro-LED array.

31 March 2020

1 reference

A FLEX switch targets Channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mapping

31 March 2020

1 reference

High-resolution labeling and functional manipulation of specific neuron types in mouse brain by Cre-activated viral gene expression

31 March 2020

1 reference

Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning

31 March 2020

1 reference

In vivo light-induced activation of neural circuitry in transgenic mice expressing channelrhodopsin-2.

31 March 2020

1 reference

Cell type–specific channelrhodopsin-2 transgenic mice for optogenetic dissection of neural circuitry function

31 March 2020

1 reference

A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex.

31 March 2020

1 reference

Optetrode: a multichannel readout for optogenetic control in freely moving mice

31 March 2020

1 reference

Integrated device for combined optical neuromodulation and electrical recording for chronic in vivo applications.

31 March 2020

1 reference

Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement

31 March 2020

1 reference

Global and local fMRI signals driven by neurons defined optogenetically by type and wiring

31 March 2020

1 reference

Optical probing of neuronal circuits with calcium indicators

31 March 2020

1 reference

Optogenetics meets optical wavefront shaping

31 March 2020

1 reference

Channelrhodopsin-2-assisted circuit mapping of long-range callosal projections

31 March 2020

1 reference

The subcellular organization of neocortical excitatory connections

31 March 2020

1 reference

Lateral competition for cortical space by layer-specific horizontal circuits

31 March 2020

1 reference

Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolution

31 March 2020

1 reference

Improved expression of halorhodopsin for light-induced silencing of neuronal activity

31 March 2020

1 reference

eNpHR: a Natronomonas halorhodopsin enhanced for optogenetic applications

31 March 2020

1 reference

Characterization of engineered channelrhodopsin variants with improved properties and kinetics

31 March 2020

1 reference

Neocortical excitation/inhibition balance in information processing and social dysfunction

31 March 2020

1 reference

Imaging synaptic inhibition with the genetically encoded chloride indicator Clomeleon

31 March 2020

1 reference

Cholinergic interneurons control local circuit activity and cocaine conditioning

31 March 2020

1 reference

Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry

31 March 2020

1 reference

Optogenetic interrogation of dopaminergic modulation of the multiple phases of reward-seeking behavior

31 March 2020

1 reference

Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

31 March 2020

1 reference

Driving fast-spiking cells induces gamma rhythm and controls sensory responses

31 March 2020

1 reference

Optical deconstruction of parkinsonian neural circuitry

31 March 2020

1 reference

Amygdala circuitry mediating reversible and bidirectional control of anxiety

31 March 2020

1 reference

AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training

31 March 2020

1 reference

Activation of groups of excitatory neurons in the mammalian spinal cord or hindbrain evokes locomotion

31 March 2020

1 reference

Selective viral vector transduction of ErbB4 expressing cortical interneurons in vivo with a viral receptor-ligand bridge protein.

31 March 2020

1 reference

Targeted entry via somatostatin receptors using a novel modified retrovirus glycoprotein that delivers genes at levels comparable to those of wild-type viral glycoproteins

31 March 2020

1 reference

Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking

31 March 2020

1 reference

Multiwaveguide implantable probe for light delivery to sets of distributed brain targets

31 March 2020

1 reference

A wirelessly powered and controlled device for optical neural control of freely-behaving animals

31 March 2020

1 reference

Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication

31 March 2020

1 reference

Efficacy of drug treatments for generalised anxiety disorder: systematic review and meta-analysis

31 March 2020

1 reference

Optical activation of lateral amygdala pyramidal cells instructs associative fear learning

31 March 2020

1 reference

Fear and the human amygdala.

31 March 2020

1 reference

The role of the amygdala in fear and anxiety

31 March 2020

1 reference

Emotion: clues from the brain

31 March 2020

1 reference

The Amygdala, Fear, and Memory

31 March 2020

1 reference

Synaptic mechanisms of associative memory in the amygdala.

31 March 2020

1 reference

Neuropeptide S-mediated control of fear expression and extinction: role of intercalated GABAergic neurons in the amygdala

31 March 2020

1 reference

The lateral amygdaloid nucleus: sensory interface of the amygdala in fear conditioning

31 March 2020

1 reference

Blocking of acquisition but not expression of conditioned fear-potentiated startle by NMDA antagonists in the amygdala

31 March 2020

1 reference

New vistas on amygdala networks in conditioned fear

31 March 2020

1 reference

Intra-amygdala blockade of the NR2B subunit of the NMDA receptor disrupts the acquisition but not the expression of fear conditioning.

31 March 2020

1 reference

Rethinking the fear circuit: the central nucleus of the amygdala is required for the acquisition, consolidation, and expression of Pavlovian fear conditioning.

31 March 2020

1 reference

Selective erasure of a fear memory

31 March 2020

1 reference

Genetic dissection of an amygdala microcircuit that gates conditioned fear

31 March 2020

1 reference

Encoding of conditioned fear in central amygdala inhibitory circuits

31 March 2020

1 reference

Post-traumatic stress disorder

31 March 2020

1 reference

Neurocircuitry models of posttraumatic stress disorder and extinction: human neuroimaging research--past, present, and future

31 March 2020

1 reference

Fear extinction in rats: implications for human brain imaging and anxiety disorders

31 March 2020

1 reference

Contextual fear, gestalt memories, and the hippocampus

31 March 2020

1 reference

Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning

31 March 2020

1 reference

Memory--a century of consolidation

31 March 2020

1 reference

Consolidation of CS and US representations in associative fear conditioning

31 March 2020

1 reference

The organization of recent and remote memories

31 March 2020

1 reference

New circuits for old memories: the role of the neocortex in consolidation

31 March 2020

1 reference

Independent cellular processes for hippocampal memory consolidation and reconsolidation

31 March 2020

1 reference

Dynamics of retrieval strategies for remote memories.

31 March 2020

1 reference

Drugs of abuse: anatomy, pharmacology and function of reward pathways

31 March 2020

1 reference

Drug-activation of brain reward pathways.

31 March 2020

1 reference

Neural systems of reinforcement for drug addiction: from actions to habits to compulsion

31 March 2020

1 reference

The neural basis of drug craving: an incentive-sensitization theory of addiction

31 March 2020

1 reference

The neuroscience of natural rewards: relevance to addictive drugs.

31 March 2020

1 reference

A neural substrate of prediction and reward

31 March 2020

1 reference

The dopamine hypothesis of reward: past and current status

31 March 2020

1 reference

What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?

31 March 2020

1 reference

The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking

31 March 2020

1 reference

Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity

31 March 2020

1 reference

Basolateral amygdala neurons facilitate reward-seeking behavior by exciting nucleus accumbens neurons

31 March 2020

1 reference

Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex

31 March 2020

1 reference

Firing of nucleus accumbens neurons during the consummatory phase of a discriminative stimulus task depends on previous reward predictive cues

31 March 2020

1 reference

Measuring reward with the conditioned place preference paradigm: a comprehensive review of drug effects, recent progress and new issues

31 March 2020

1 reference

Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward

31 March 2020

1 reference

Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain

31 March 2020

1 reference

Drug-evoked synaptic plasticity in addiction: from molecular changes to circuit remodeling

31 March 2020

1 reference

Orbitofrontal cortex and basolateral amygdala encode expected outcomes during learning

31 March 2020

1 reference

Orbitofrontal cortex, associative learning, and expectancies

31 March 2020

1 reference

Rapid strengthening of thalamo-amygdala synapses mediates cue-reward learning

31 March 2020

1 reference

Methylphenidate facilitates learning-induced amygdala plasticity

31 March 2020

1 reference

A comparison of nucleus accumbens neuronal firing patterns during cocaine self-administration and water reinforcement in rats.

31 March 2020

1 reference

Evidence that separate neural circuits in the nucleus accumbens encode cocaine versus "natural" (water and food) reward.

31 March 2020

1 reference

Dissociation of the role of nucleus accumbens dopamine in responding to reward-predictive cues and waiting for reward

31 March 2020

1 reference

Prefrontal cortical cell firing during maintenance, extinction, and reinstatement of goal-directed behavior for natural reward.

31 March 2020

1 reference

Amygdala neural encoding of the absence of reward during extinction.

31 March 2020

1 reference

Amygdala neurons differentially encode motivation and reinforcement

31 March 2020

1 reference

Subsecond dopamine release promotes cocaine seeking.

31 March 2020

1 reference

Enhanced sucrose and cocaine self-administration and cue-induced drug seeking after loss of VGLUT2 in midbrain dopamine neurons in mice.

31 March 2020

1 reference

Research: Methods, Mechanisms, and Causes Introduction

31 March 2020

1 reference

Dopamine, depression and antidepressants

31 March 2020

1 reference

The compliance with antidepressants in general practice

31 March 2020

1 reference

The effects of adherence to antidepressant treatment guidelines on relapse and recurrence of depression.

31 March 2020

1 reference

Deep brain stimulation for treatment-resistant depression

31 March 2020

1 reference

Modulating limbic-cortical circuits in depression: targets of antidepressant treatments

31 March 2020

1 reference

Antidepressant effect of optogenetic stimulation of the medial prefrontal cortex

31 March 2020

1 reference

Neuronal tryptophan hydroxylase mRNA expression in the human dorsal and median raphe nuclei: major depression and suicide

31 March 2020

1 reference

Freewheel running prevents learned helplessness/behavioral depression: role of dorsal raphe serotonergic neurons.

31 March 2020

1 reference

Altered depression-related behaviors and functional changes in the dorsal raphe nucleus of serotonin transporter-deficient mice

31 March 2020

1 reference

High-speed imaging reveals neurophysiological links to behavior in an animal model of depression

31 March 2020

1 reference

Hippocampal volume reduction in major depression.

31 March 2020

1 reference

Adult hippocampal neurogenesis in depression

31 March 2020

1 reference

The possibility of neurotoxicity in the hippocampus in major depression: a primer on neuron death

31 March 2020

1 reference

Quantitative MRI of the hippocampus and amygdala in severe depression

31 March 2020

1 reference

Amygdala core nuclei volumes are decreased in recurrent major depression.

31 March 2020

1 reference

Increased amygdala response to masked emotional faces in depressed subjects resolves with antidepressant treatment: an fMRI study

31 March 2020

1 reference

Increased amygdala and decreased dorsolateral prefrontal BOLD responses in unipolar depression: related and independent features.

31 March 2020

1 reference

In vivo evidence for the involvement of dopamine-D2 receptors in striatum and anterior cingulate gyrus in major depression.

31 March 2020

1 reference

Stress-induced depressive behaviors are correlated with Par-4 and DRD2 expression in rat striatum

31 March 2020

1 reference

Lower dopamine transporter binding potential in striatum during depression

31 March 2020

1 reference

Involvement of dopamine receptors in the antidepressant-like effect of melatonin in the tail suspension test.

31 March 2020

1 reference

Dopamine and depression: A review of recent evidence. II. Theoretical approaches

31 March 2020

1 reference

Deep brain stimulation of the ventral capsule/ventral striatum for treatment-resistant depression.

31 March 2020

1 reference

Serotonin-Containing Neurons in Brain: Depression of Firing by Monoamine Oxidase Inhibitors

31 March 2020

1 reference

Serotonin brain circuits involved in major depression and suicide

31 March 2020

1 reference

Review of pharmacological treatment in mood disorders and future directions for drug development.

31 March 2020

1 reference

Anxiety in high-functioning children with autism

31 March 2020

1 reference

Defining autism spectrum disorders.

31 March 2020

1 reference

Molecular pathology of schizophrenia: more than one disease process?

31 March 2020

1 reference

A diagnostic interview: the schedule for affective disorders and schizophrenia

31 March 2020

1 reference

The positive and negative syndrome scale (PANSS) for schizophrenia

31 March 2020

1 reference

Altered Excitatory-Inhibitory Balance in the NMDA-Hypofunction Model of Schizophrenia

31 March 2020

1 reference

Alterations of cortical GABA neurons and network oscillations in schizophrenia.

31 March 2020

1 reference

Pathophysiologically based treatment interventions in schizophrenia

31 March 2020

1 reference

Optogenetic control of epileptiform activity

31 March 2020

1 reference

A new mode of corticothalamic transmission revealed in the Gria4(-/-) model of absence epilepsy

31 March 2020

1 reference

The Intense World Theory – A Unifying Theory of the Neurobiology of Autism

31 March 2020

1 reference

A computational model for cerebral cortical dysfunction in autism spectrum disorders

31 March 2020

1 reference

Model of autism: increased ratio of excitation/inhibition in key neural systems

31 March 2020

1 reference

Excess of high frequency electroencephalogram oscillations in boys with autism

31 March 2020

1 reference

The neural basis of addiction: a pathology of motivation and choice

31 March 2020

1 reference

Addiction and schizophrenia

31 March 2020

1 reference

Quality of life in schizophrenia: contributions of anxiety and depression

31 March 2020

1 reference

CCK, schizophrenia, and anxiety. CCK-B antagonists inhibit the activity of brain dopamine neurons

31 March 2020

1 reference

Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa

31 March 2020

1 reference

Optogenetic approaches to restoring visual function in retinitis pigmentosa.

31 March 2020

1 reference

Active expiration induced by excitation of ventral medulla in adult anesthetized rats

31 March 2020

1 reference

Astrocytes control breathing through pH-dependent release of ATP

31 March 2020

1 reference

Functional architecture of basal ganglia circuits: neural substrates of parallel processing

31 March 2020

1 reference

A computational model of action selection in the basal ganglia. I. A new functional anatomy.

31 March 2020

1 reference

Behavioural assessment of mice lacking D1A dopamine receptors

31 March 2020

1 reference

Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases

31 March 2020

1 reference

Diagnostic criteria for Parkinson disease

31 March 2020

1 reference

Deep brain stimulation for Parkinson’s disease

31 March 2020

1 reference

A randomized trial of deep-brain stimulation for Parkinson's disease.

31 March 2020

1 reference

Double-blind evaluation of subthalamic nucleus deep brain stimulation in advanced Parkinson's disease.

31 March 2020

1 reference

SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate α-synuclein and are susceptible to oxidative stress

31 March 2020

1 reference

Functional identification of an aggression locus in the mouse hypothalamus

31 March 2020

1 reference

Optogenetics: background and concepts for neurosurgery

31 March 2020

1 reference

Millisecond-timescale optical control of neural dynamics in the nonhuman primate brain

31 March 2020

1 reference

The dawning of primate optogenetics

31 March 2020

1 reference

Myosin-dependent targeting of transmembrane proteins to neuronal dendrites

31 March 2020

1 reference

Ultra light-sensitive and fast neuronal activation with the Ca²+-permeable channelrhodopsin CatCh.

31 March 2020

1 reference

Crystal structure of the channelrhodopsin light-gated cation channel

31 March 2020

1 reference

Contextual fear conditioning, conjunctive representations, pattern completion, and the hippocampus.

31 March 2020

1 reference

12 December 2020

Definitions of antidepressant treatment response, remission, nonresponse, partial response, and other relevant outcomes: a focus on treatment-resistant depression

1 reference

12 December 2020

Benzodiazepines: use, abuse, and consequences

1 reference

12 December 2020

Anxiety disorders: clinical presentation and epidemiology.

1 reference

12 December 2020

Prosthetic systems for therapeutic optical activation and silencing of genetically-targeted neurons

1 reference

12 December 2020

Construction of implantable optical fibers for long-term optogenetic manipulation of neural circuits

1 reference

12 December 2020

The prevalence and distribution of major depression in a national community sample: the National Comorbidity Survey

1 reference

12 December 2020

Effects of amygdala, hippocampus, and periaqueductal gray lesions on short- and long-term contextual fear

1 reference

12 December 2020

Psychobiologic mechanisms of posttraumatic stress disorder

1 reference

12 December 2020

Microcircuitry of the direct and indirect pathways of the basal ganglia

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRN3171

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6682316&resulttype=core&format=json

Dimensions Publication ID

11 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6682316&resulttype=core&format=json

11 May 2020

PubMed publication ID

22430017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6682316&resulttype=core&format=json