(Q37994998)

26 August 2017

title

Energy metabolism and proliferation in pancreatic carcinogenesis (English)

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26 August 2017

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4

Mert Erkan

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26 August 2017

Ivonne Regel

1

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26 August 2017

Bo Kong

2

1 reference

26 August 2017

Susanne Raulefs

3

1 reference

26 August 2017

Christoph W Michalski

5

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26 August 2017

Mark Hartel

6

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26 August 2017

Jörg Kleeff

7

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26 August 2017

language of work or name

English

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publication date

20 March 2012

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Langenbeck's Archives of Surgery

26 August 2017

published in

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26 August 2017

volume

397

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26 August 2017

issue

4

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26 August 2017

page(s)

507-512

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The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

26 August 2017

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21 January 2018

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Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

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DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer.

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21 January 2018

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Pancreatic ductal adenocarcinoma and transcription factors: role of c-Myc

21 January 2018

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21 January 2018

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Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

21 January 2018

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MYC-induced cancer cell energy metabolism and therapeutic opportunities

21 January 2018

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21 January 2018

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21 January 2018

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TIGAR, a p53-inducible regulator of glycolysis and apoptosis

21 January 2018

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Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53

21 January 2018

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Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

21 January 2018

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Cancer risks in LKB1 germline mutation carriers.

21 January 2018

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Genome profiling of pancreatic adenocarcinoma

21 January 2018

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LKB1-dependent signaling pathways

21 January 2018

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Functional expression of the cre-lox site-specific recombination system in the yeast Saccharomyces cerevisiae

21 January 2018

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21 January 2018

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Insulin-promoter-factor 1 is required for pancreas development in mice

21 January 2018

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The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas

21 January 2018

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The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

21 January 2018

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Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

21 January 2018

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Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

21 January 2018

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Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice

21 January 2018

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Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

21 January 2018

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Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms

21 January 2018

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LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest

21 January 2018

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Conditional inactivation of Myc impairs development of the exocrine pancreas.

21 January 2018

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21 January 2018

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21 January 2018

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Pancreatic Inactivation of c-Myc Decreases Acinar Mass and Transdifferentiates Acinar Cells Into Adipocytes in Mice

21 January 2018

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21 January 2018

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12 December 2020

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12 December 2020

p16 and K-ras gene mutations in the intraductal precursors of human pancreatic adenocarcinoma

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12 December 2020

Pancreatic adenocarcinomas frequently show p53 gene mutations.

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12 December 2020

K-ras and p53 gene mutations in pancreatic cancer: ductal and nonductal tumors progress through different genetic lesions.

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12 December 2020

The fundamental role of the p53 pathway in tumor metabolism and its implication in tumor therapy

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12 December 2020

c-MYC activation in primary and metastatic ductal adenocarcinoma of the pancreas: incidence, mechanisms, and clinical significance

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12 December 2020

10.1007/S00423-012-0933-9

Identifiers

DOI

1 reference

26 August 2017

1 reference