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English
Ubiquitination in signaling to and activation of IKK.
scientific article published on March 2012
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scholarly article
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stated in
Europe PubMed Central
PMC publication ID
3549672
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
title
Ubiquitination in signaling to and activation of IKK
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3549672
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
main subject
protein ubiquitination
1 reference
based on heuristic
inferred from title
author
Zhijian Chen
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3549672
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
author name string
Zhijian J Chen
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3549672
retrieved
26 August 2017
language of work or name
English
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inferred from title
publication date
1 March 2012
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Europe PubMed Central
PMC publication ID
3549672
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
published in
Immunological Reviews
1 reference
stated in
Europe PubMed Central
PMC publication ID
3549672
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
volume
246
1 reference
stated in
Europe PubMed Central
PMC publication ID
3549672
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
issue
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3549672
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
page(s)
95-106
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stated in
Europe PubMed Central
PMC publication ID
3549672
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
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TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity
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Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling
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RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
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6 September 2017
Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
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Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]
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6 September 2017
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
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TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains
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6 September 2017
TNF-R1 signaling: a beautiful pathway
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6 September 2017
Ubiquitin enters the new millennium
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6 September 2017
Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death
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6 September 2017
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
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6 September 2017
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
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6 September 2017
RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination
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6 September 2017
Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice
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6 September 2017
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
Identification of the receptor component of the IkappaBalpha-ubiquitin ligase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
NF-kappa B: ten years after
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
TRAF6 is a signal transducer for interleukin-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
Thermolability of ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
Multiple nuclear factors interact with the immunoglobulin enhancer sequences
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
Cyclin is degraded by the ubiquitin pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
6 September 2017
c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
14 September 2017
Direct, noncatalytic mechanism of IKK inhibition by A20.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
14 September 2017
Ubiquitin: Roles in protein modification and breakdown
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
14 September 2017
The Ripoptosome: death decision in the cytosol.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
31 August 2018
Spontaneous mutations in the mouse Sharpin gene result in multiorgan inflammation, immune system dysregulation and dermatitis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
31 August 2018
TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
31 August 2018
The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
31 August 2018
In vitro assembly and recognition of Lys-63 polyubiquitin chains
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3549672
retrieved
31 August 2018
Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22435549
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
TRAF6 is a T cell-intrinsic negative regulator required for the maintenance of immune homeostasis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22435549
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
NF-kappaB activation: Nondegradative ubiquitination implicates NEMO
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22435549
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cutting Edge: Pivotal function of Ubc13 in thymocyte TCR signaling
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22435549
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1111/J.1600-065X.2012.01108.X
1 reference
stated in
Europe PubMed Central
PMC publication ID
3549672
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
PMC publication ID
3549672
1 reference
stated in
Europe PubMed Central
PMC publication ID
3549672
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
PubMed publication ID
22435549
1 reference
stated in
Europe PubMed Central
PMC publication ID
3549672
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22435549%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
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