(Q37999397)

26 August 2017

title

CD28-specific immunomodulating antibodies: what can be learned from experimental models? (English)

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26 August 2017

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N Poirier

1

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26 August 2017

G Blancho

series ordinal

2

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26 August 2017

B Vanhove

series ordinal

3

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26 August 2017

language of work or name

English

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publication date

4 April 2012

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American Journal of Transplantation

26 August 2017

published in

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26 August 2017

volume

12

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26 August 2017

issue

7

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26 August 2017

page(s)

1682-1690

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Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses

26 August 2017

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B7-h2 is a costimulatory ligand for CD28 in human

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Manipulation of regulatory T-cell number and function with CD28-specific monoclonal antibodies

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A CD28 superagonistic antibody elicits 2 functionally distinct waves of T cell activation in rats

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Rapid regulatory T-cell response prevents cytokine storm in CD28 superagonist treated mice

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Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis

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Polyclonal expansion of regulatory T cells interferes with effector cell migration in a model of multiple sclerosis.

21 January 2018

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A superagonistic monoclonal antibody for CD28 ameliorates crescentic glomerulonephritis in wistar-kyoto rats

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CD28 superagonists: what makes the difference in humans?

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Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412

21 January 2018

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Signaling signatures and functional properties of anti-human CD28 superagonistic antibodies

21 January 2018

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Monoclonal antibody TGN1412 trial failure explained by species differences in CD28 expression on CD4+ effector memory T-cells

21 January 2018

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Relative over-reactivity of human versus chimpanzee lymphocytes: implications for the human diseases associated with immune activation

21 January 2018

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Loss of Siglec expression on T lymphocytes during human evolution

21 January 2018

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Selective blockade of CD28 and not CTLA-4 with a single-chain Fv-alpha1-antitrypsin fusion antibody

21 January 2018

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Blockade of costimulation through B7/CD28 inhibits experimental autoimmune uveoretinitis, but does not induce long-term tolerance.

21 January 2018

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Neonatal activation of CD28 signaling overcomes T cell anergy and prevents autoimmune diabetes by an IL-4-dependent mechanism.

21 January 2018

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Protection from graft-versus-host disease with a novel B7 binding site-specific mouse anti-mouse CD28 monoclonal antibody

21 January 2018

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Differential effect of CD28 versus B7 blockade on direct pathway of allorecognition and self-restricted responses

21 January 2018

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Anti-CD28 antibody-induced kidney allograft tolerance related to tryptophan degradation and TCR class II B7 regulatory cells

21 January 2018

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A blocking anti-CD28-specific antibody induces long-term heart allograft survival by suppression of the PKC theta-JNK signal pathway.

21 January 2018

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FR255734, a humanized, Fc-Silent, Anti-CD28 antibody, improves psoriasis in the SCID mouse-psoriasis xenograft model

21 January 2018

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Induction of alloantigen-specific hyporesponsiveness in human T lymphocytes by blocking interaction of CD28 with its natural ligand B7/BB1

21 January 2018

1 reference

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Inducing CTLA-4-dependent immune regulation by selective CD28 blockade promotes regulatory T cells in organ transplantation

21 January 2018

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Reversal of the TCR stop signal by CTLA-4

21 January 2018

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Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

21 January 2018

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Selective CD28 blockade attenuates acute and chronic rejection of murine cardiac allografts in a CTLA-4-dependent manner

21 January 2018

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The effect of costimulatory and interleukin 2 receptor blockade on regulatory T cells in renal transplantation

21 January 2018

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A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study).

21 January 2018

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Cutting Edge: CD28 Controls Peripheral Homeostasis of CD4+CD25+ Regulatory T Cells

21 January 2018

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B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

21 January 2018

1 reference

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Two functional subsets of FOXP3+ regulatory T cells in human thymus and periphery

21 January 2018

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Murine regulatory T cells contain hyperproliferative and death-prone subsets with differential ICOS expression

21 January 2018

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All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation

21 January 2018

1 reference

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Strong CD28 costimulation suppresses induction of regulatory T cells from naive precursors through Lck signaling

21 January 2018

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TGF-beta induces Foxp3 + T-regulatory cells from CD4 + CD25 - precursors

21 January 2018

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TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells

21 January 2018

1 reference

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Targeted CTLA-4 engagement induces CD4+CD25+CTLA-4high T regulatory cells with target (allo)antigen specificity.

21 January 2018

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IDO expression by dendritic cells: tolerance and tryptophan catabolism

21 January 2018

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Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

21 January 2018

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The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation

21 January 2018

1 reference

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21 January 2018

The B7 family revisited

1 reference

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CTLA-4 control over Foxp3+ regulatory T cell function

21 January 2018

1 reference

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Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2012.04032.X

Three-year outcomes from BENEFIT, a randomized, active-controlled, parallel-group study in adult kidney transplant recipients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2012.04032.X

Efficient expansion of regulatory T cells in vitro and in vivo with a CD28 superagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2012.04032.X

Costimulation and autoimmune diabetes in BB rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2012.04032.X

CTLA-4-Ig therapy diminishes the frequency but enhances the function of Treg cells in patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2012.04032.X

Deleterious effect of CTLA4-Ig on a Treg-dependent transplant model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2012.04032.X

Distinct T cell dynamics in lymph nodes during the induction of tolerance and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-6143.2012.04032.X

10.1111/J.1600-6143.2012.04032.X

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference