(Q38002928)

26 August 2017

title

A tan in a test tube - in vitro models for investigating ultraviolet radiation-induced damage in skin (English)

1 reference

26 August 2017

main subject

ultraviolet radiation

1 reference

Michael G Kimlin

4

0 references

Zee Upton

series ordinal

5

object named as

Zee Upton

1 reference

26 August 2017

Tara L Fernandez

1

1 reference

26 August 2017

Rebecca A Dawson

series ordinal

2

1 reference

26 August 2017

Derek R Van Lonkhuyzen

series ordinal

3

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26 August 2017

publication date

16 April 2012

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26 August 2017

published in

Experimental Dermatology

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26 August 2017

volume

21

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26 August 2017

issue

6

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26 August 2017

page(s)

404-410

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Molecular mechanisms of photocarcinogenesis

26 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Neuroendocrinology of the skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

What is the 'true' function of skin?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Skin as an endocrine organ: implications for its function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Differential expression of HPA axis homolog in the skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Cutaneous expression of corticotropin-releasing hormone (CRH), urocortin, and CRH receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Corticotropin-releasing hormone induces keratinocyte differentiation in the adult human epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Melanocyte-stimulating hormone directly enhances UV-Induced DNA repair in keratinocytes by a xeroderma pigmentosum group A-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Potential mechanism of skin response to stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Neuroendocrine activity of the melanocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Inhibition of TASK-3 (KCNK9) channel biosynthesis changes cell morphology and decreases both DNA content and mitochondrial function of melanoma cells maintained in cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Co-overexpression of Bag-1 and heat shock protein 70 in human epidermal squamous cell carcinoma: Bag-1-mediated resistance to 5-fluorouracil-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Protective effects of platinum nanoparticles against UV‐light‐induced epidermal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

The influence of culture time and passage number on the morphological and physiological development of Caco-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Collagen VI protects against neuronal apoptosis elicited by ultraviolet irradiation via an Akt/phosphatidylinositol 3-kinase signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Influence of extracellular matrix proteins on human keratinocyte attachment, proliferation and transfer to a dermal wound model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

The IGF-1/IGF-1R signaling axis in the skin: a new role for the dermis in aging-associated skin cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Photocarcinogenesis: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Recent advances in sunlight-induced carcinogenesis using the Xiphophorus melanoma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Temozolomide-mediated radiosensitization of human glioma cells in a zebrafish embryonic system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

A mutated EGFR is sufficient to induce malignant melanoma with genetic background-dependent histopathologies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Ultraviolet A does not induce melanomas in a Xiphophorus hybrid fish model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Histopathology of melanocytic lesions in goats and establishment of a melanoma cell line: a potential model for human melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Inflammation, gene mutation and photoimmunosuppression in response to UVR-induced oxidative damage contributes to photocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Multistep skin cancer in mice as a model to study the evolution of cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Ki-67 immunostaining of normal human epidermis: comparison with 3H-thymidine labelling and PCNA immunostaining

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Animals under the sun: effects of ultraviolet radiation on mammalian skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Populations of p53 codon 270 CGT to TGT mutant cells in SKH-1 mouse skin tumors induced by simulated solar light

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Impact of Nrf2 on UVB-induced skin inflammation/photoprotection and photoprotective effect of sulforaphane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Acute exposure to solar simulated ultraviolet radiation affects oxidative stress-related biomarkers in skin, liver and blood of hairless mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Aberrant DNA hypermethylation patterns lead to transcriptional silencing of tumor suppressor genes in UVB-exposed skin and UVB-induced skin tumors of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Somatic p16(INK4a) loss accelerates melanomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Targeted delivery of NRASQ61R and Cre-recombinase to post-natal melanocytes induces melanoma in Ink4a/Arflox/lox mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Effects of baicalein and wogonin isolated from Scutellaria baicalensis roots on skin damage in acute UVB-irradiated hairless mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Effects of exogenous MSH on the transformation from phaeo- to eumelanogenesis within C57BL/6J-Ay/a hairbulb melanocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Cyclosporine a mediates pathogenesis of aggressive cutaneous squamous cell carcinoma by augmenting epithelial-mesenchymal transition: role of TGFβ signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Photocarcinogenesis in human adult skin grafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Differential roles of the pRb and Arf/p53 pathways in murine naevus and melanoma genesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Murine neonatal melanocytes exhibit a heightened proliferative response to ultraviolet radiation and migrate to the epidermal basal layer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Melanogenesis is coupled to murine anagen: toward new concepts for the role of melanocytes and the regulation of melanogenesis in hair growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Hair follicle pigmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

The influence of the hair cycle on the thickness of mouse skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Differential Expression and Activity of Melanogenesis-Related Proteins During Induced Hair Growth in Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

25 Hydroxyvitamin D 1 alpha-hydroxylase is required for optimal epidermal differentiation and permeability barrier homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Effect of Vitamin D3 receptor ablation on murine mammary gland development and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Scatter factor/hepatocyte growth factor as a regulator of skeletal muscle and neural crest development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Effect of the spectral range of a UV lamp on the production of cyclobutane pyrimidine dimers in human skin in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

The effect of ultraviolet (UV) A1, UVB and solar-simulated radiation on p53 activation and p21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Assessment of the Photoprotection Properties of Sunscreens by Chromatographic Measurement of DNA Damage in Skin Explants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Development and characterisation of an in vitro photomicronucleus test using ex vivo human skin tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Quantitative analysis of the proliferation of epidermal cells using a human skin organ culture system and the effect of DbcAMP using markers of proliferation (BrdU, Ki-67, PCNA).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Skin constructs for replacement of skin tissues for in vitro testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

The use of polymers for dermal and transdermal delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Synthesis and characterization of a model extracellular matrix that induces partial regeneration of adult mammalian skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

A simple reconstructed human epidermis: preparation of the culture model and utilization in in vitro studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Protective effect of matrix metalloproteinase inhibitors against epidermal basement membrane damage: skin equivalents partially mimic photoageing process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Comparison of an in vitro skin model to normal human skin for dermatological research

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

The use of reconstructed human skin to evaluate UV-induced modifications and sunscreen efficacy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

GammaH2AX, an accurate marker that analyzes UV genotoxic effects on human keratinocytes and on human skin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Use of peracetic acid to sterilize human donor skin for production of acellular dermal matrices for clinical use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Optimization and characterization of an engineered human skin equivalent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Ultraviolet irradiation induces keratinocyte proliferation and epidermal hyperplasia through the activation of the epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Molecular mechanism of ultraviolet-induced keratinocyte apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Successive alteration and recovery of epidermal differentiation and morphogenesis after specific UVB-damages in skin reconstructed in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Epidermal growth factor receptor/beta-catenin/T-cell factor 4/matrix metalloproteinase 1: a new pathway for regulating keratinocyte invasiveness after UVA irradiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Astaxanthin attenuates the UVA-induced up-regulation of matrix-metalloproteinase-1 and skin fibroblast elastase in human dermal fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

CDK4 coexpression with Ras generates malignant human epidermal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Corrective gene transfer in the human skin disorder lamellar ichthyosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Mechanistic effects of long-term ultraviolet B irradiation induce epidermal and dermal changes in human skin xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

The regulation of normal melanocyte proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

BRAF, HRAS, KRAS, NRAS and CDKN2A genes analysis in cultured melanocytes used for vitiligo treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Molecular and functional analysis of cadherin-based adherens junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Reconstruction of a tissue-engineered skin containing melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Pigmented human skin equivalent--as a model of the mechanisms of control of cell-cell and cell-matrix interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Co-culture of human melanocytes and keratinocytes in a skin equivalent model: effect of ultraviolet radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Quercetin-induced melanogenesis in a reconstituted three-dimensional human epidermal model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Isolation, differentiation and characterization of vascular cells derived from human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Resistance of CD1d-/- mice to ultraviolet-induced skin cancer is associated with increased apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Differential activity of UV-DDB in mouse keratinocytes and fibroblasts: impact on DNA repair and UV-induced skin cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

PKCepsilon overexpression, irrespective of genetic background, sensitizes skin to UVR-induced development of squamous-cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Initial studies on an in vivo action spectrum for melanoma induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Animal models of melanoma: an HGF/SF transgenic mouse model may facilitate experimental access to UV initiating events

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Applications of the human p53 knock-in (Hupki) mouse model for human carcinogen testing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Humanized MC1R transgenic mice reveal human specific receptor function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Gain-of-function mutant p53 but not p53 deletion promotes head and neck cancer progression in response to oncogenic K-ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Modulation of basal and squamous cell carcinoma by endogenous estrogen in mouse models of skin cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Synergistic effects of combined phytochemicals and skin cancer prevention in SENCAR mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Effects of high-fat diets rich in either omega-3 or omega-6 fatty acids on UVB-induced skin carcinogenesis in SKH-1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Increased IKKα expression in the basal layer of the epidermis of transgenic mice enhances the malignant potential of skin tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Inhibition of melanoma growth after treatment with dendritic cells in a Tyr-SV40E murine model requires CD4+ T cells but not CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Overexpression of hedgehog signaling is associated with epidermal tumor formation in vitamin D receptor-null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

Influences of p53 deficiency on the apoptotic response, DNA damage removal and mutagenesis in UVB-exposed mouse skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01485.X

10.1111/J.1600-0625.2012.01485.X

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference