(Q38004594)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22524425%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Beyond glycoproteins as galectin counterreceptors: tumor-effector T cell growth control via ganglioside GM1 [corrected] (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22524425%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

3

1 reference

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29 January 2020

Herbert Kaltner

6

1 reference

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29 January 2020

Hans-Joachim Gabius

8

1 reference

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29 January 2020

author name string

Robert W Ledeen

1

1 reference

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29 January 2020

Gusheng Wu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22524425%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

David Bleich

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22524425%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Guillemette Huet

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22524425%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Jürgen Kopitz

7

1 reference

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29 January 2020

language of work or name

English

0 references

publication date

1 April 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22524425%20AND%20SRC:MED&resulttype=core&format=json

Annals of the New York Academy of Sciences

29 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22524425%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

1253

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22524425%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

206-221

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22524425%20AND%20SRC:MED&resulttype=core&format=json

Precision mapping of an in vivo N-glycoproteome reveals rigid topological and sequence constraints.

29 January 2020

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Role of glycosylation in development

21 January 2018

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Compensation of loss of protein function in microsatellite-unstable colon cancer cells (HCT116): a gene-dependent effect on the cell surface glycan profile.

21 January 2018

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Nitric oxide changes distinct aspects of the glycophenotype of human neuroblastoma NB69 cells.

21 January 2018

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From structural to functional glycomics: core substitutions as molecular switches for shape and lectin affinity of N-glycans

21 January 2018

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The repertoire of glycan determinants in the human glycome

21 January 2018

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Regulation of intracellular signaling by extracellular glycan remodeling.

21 January 2018

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From lectin structure to functional glycomics: principles of the sugar code.

21 January 2018

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Clusters, bundles, arrays and lattices: novel mechanisms for lectin-saccharide-mediated cellular interactions

21 January 2018

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Functions of cell surface galectin-glycoprotein lattices

21 January 2018

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Glycosylation, galectins and cellular signaling

21 January 2018

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Growth-regulatory human galectin-1: crystallographic characterisation of the structural changes induced by single-site mutations and their impact on the thermodynamics of ligand binding

21 January 2018

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Galectin-1 interacts with the {alpha}5{beta}1 fibronectin receptor to restrict carcinoma cell growth via induction of p21 and p27.

21 January 2018

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Galectin-1 sensitizes carcinoma cells to anoikis via the fibronectin receptor α5β1-integrin.

21 January 2018

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The ST6Gal I sialyltransferase selectively modifies N-glycans on CD45 to negatively regulate galectin-1-induced CD45 clustering, phosphatase modulation, and T cell death

21 January 2018

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Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death

21 January 2018

1 reference

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Tumor suppressor p16INK4a--modulator of glycomic profile and galectin-1 expression to increase susceptibility to carbohydrate-dependent induction of anoikis in pancreatic carcinoma cells

21 January 2018

1 reference

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A novel function for the tumor suppressor p16(INK4a): induction of anoikis via upregulation of the alpha(5)beta(1) fibronectin receptor

21 January 2018

1 reference

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Tumor suppressor p16 INK4a: Downregulation of galectin-3, an endogenous competitor of the pro-anoikis effector galectin-1, in a pancreatic carcinoma model.

21 January 2018

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Galectin-glycan lattices regulate cell-surface glycoprotein organization and signalling

21 January 2018

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Sialic acids in T cell development and function

21 January 2018

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How does it act when soluble? Critical evaluation of mechanism of galectin-1 induced T-cell apoptosis

21 January 2018

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(Glyco)sphingolipidology: an amazing challenge and opportunity for systems biology

21 January 2018

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Gangliosides in cell recognition and membrane protein regulation

21 January 2018

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In search of a solution to the sphinx-like riddle of GM1.

21 January 2018

1 reference

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Molecular cloning and characterization of a plasma membrane-associated sialidase specific for gangliosides

21 January 2018

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Modulation of cell functions by glycosphingolipid metabolic remodeling in the plasma membrane.

21 January 2018

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Stable transfection of GM1 synthase gene into GM1-deficient NG108-15 cells, CR-72 cells, rescues the responsiveness of Trk-neurotrophin receptor to its ligand, NGF.

21 January 2018

1 reference

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Potentiation of a sodium-calcium exchanger in the nuclear envelope by nuclear GM1 ganglioside.

21 January 2018

1 reference

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Interaction of the delta-opioid receptor with GM1 ganglioside: conversion from inhibitory to excitatory mode

21 January 2018

1 reference

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Promotion of neuritogenesis in mouse neuroblastoma cells by exogenous gangliosides. Relationship between the effect and the cell association of ganglioside GM1.

21 January 2018

1 reference

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Biology of gangliosides: neuritogenic and neuronotrophic properties

21 January 2018

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Regulation of axonal development by plasma membrane gangliosides

21 January 2018

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Role of plasma membrane ganglioside sialidase of human neuroblastoma cells in growth control and differentiation

21 January 2018

1 reference

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Galectin-1 is a major receptor for ganglioside GM1, a product of the growth-controlling activity of a cell surface ganglioside sialidase, on human neuroblastoma cells in culture

21 January 2018

1 reference

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Negative regulation of neuroblastoma cell growth by carbohydrate-dependent surface binding of galectin-1 and functional divergence from galectin-3.

21 January 2018

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How adhesion/growth-regulatory galectins-1 and -3 attain cell specificity: case study defining their target on neuroblastoma cells (SK-N-MC) and marked affinity regulation by affecting microdomain organization of the membrane

21 January 2018

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Unique conformer selection of human growth-regulatory lectin galectin-1 for ganglioside GM1 versus bacterial toxins

21 January 2018

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Determination of structural and functional overlap/divergence of five proto-type galectins by analysis of the growth-regulatory interaction with ganglioside GM1 in silico and in vitro on human neuroblastoma cells

21 January 2018

1 reference

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The plasma membrane ganglioside sialidase cofractionates with markers of lipid rafts

21 January 2018

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Oligosaccharide specificity of galectins: a search by frontal affinity chromatography.

21 January 2018

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Binding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowth

21 January 2018

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Co-localization of galectin-1 with GM1 ganglioside in the course of its clathrin- and raft-dependent endocytosis

21 January 2018

1 reference

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Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis.

21 January 2018

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Galectin-1: a key effector of regulation mediated by CD4+CD25+ T cells.

21 January 2018

1 reference

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Cross-linking of GM1 ganglioside by galectin-1 mediates regulatory T cell activity involving TRPC5 channel activation: possible role in suppressing experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

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Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptor

21 January 2018

1 reference

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Immune modulation by the cholera-like enterotoxins: from adjuvant to therapeutic

21 January 2018

1 reference

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Galectin-1 is a novel functional receptor for tissue plasminogen activator in pancreatic cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Transmembrane signaling by the B subunit of cholera toxin: increased cytoplasmic free calcium in rat lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Involvement of CD2 and CD3 in galectin-1 induced signaling in human Jurkat T-cells

21 January 2018

1 reference

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The TRP ion channel family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Characterization of cholera toxin B subunit-induced Ca(2+) influx in neuroblastoma cells: evidence for a voltage-independent GM1 ganglioside-associated Ca(2+) channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Induction of calcium influx through TRPC5 channels by cross-linking of GM1 ganglioside associated with alpha5beta1 integrin initiates neurite outgrowth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

The NOD mouse: a model of immune dysregulation

21 January 2018

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The effector T cells of diabetic subjects are resistant to regulation via CD4+ FOXP3+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors

21 January 2018

1 reference

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Ganglioside GM1 deficiency in effector T cells from NOD mice induces resistance to regulatory T-cell suppression

21 January 2018

1 reference

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CD8+ T cells in autoimmunity

21 January 2018

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Quantitative differences in lipid raft components between murine CD4+ and CD8+ T cells

21 January 2018

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Cross-linking of cell surface ganglioside GM1 induces the selective apoptosis of mature CD8+ T lymphocytes

21 January 2018

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Ganglioside GM1 effects on the expression of nerve growth factor (NGF), Trk-A receptor, proinflammatory cytokines and on autoimmune diabetes onset in non-obese diabetic (NOD) mice.

21 January 2018

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Suppression of experimental allergic encephalomyelitis in Lewis rats by administration of gangliosides.

21 January 2018

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Brain-derived gangliosides suppress the chronic relapsing-remitting experimental autoimmune encephalomyelitis in NOD mice induced with myelin oligodendrocyte glycoprotein peptide.

21 January 2018

1 reference

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Th1 and Th2 cytokine immunomodulation by gangliosides in experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

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Gangliosides offer partial protection in experimental allergic neuritis

21 January 2018

1 reference

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Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Lateral compartmentalization of T cell receptor versus CD45 by galectin-N-glycan binding and microfilaments coordinate basal and activation signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation.

21 January 2018

1 reference

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Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation

21 January 2018

1 reference

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Cell surface glycans: the why and how of their functionality as biochemical signals in lectin-mediated information transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Human galectin-2: novel inducer of T cell apoptosis with distinct profile of caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Galectin-4 and small intestinal brush border enzymes form clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Lipid raft organization and function in brush borders of epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Galectin-4 and sulfatides in apical membrane trafficking in enterocyte-like cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Galectin-4-regulated delivery of glycoproteins to the brush border membrane of enterocyte-like cells

21 January 2018

1 reference

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Galectins bind to the multivalent glycoprotein asialofetuin with enhanced affinities and a gradient of decreasing binding constants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Galectin-4 binds to sulfated glycosphingolipids and carcinoembryonic antigen in patches on the cell surface of human colon adenocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Glycosylation pattern of brush border-associated glycoproteins in enterocyte-like cells: involvement of complex-type N-glycans in apical trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Secretion of the galectin family of mammalian carbohydrate-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

CD62/P-selectin recognition of myeloid and tumor cell sulfatides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Sulfated glycolipids are ligands for a lymphocyte homing receptor, L-selectin (LECAM-1), Binding epitope in sulfated sugar chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

P-selectin mediates metastatic progression through binding to sulfatides on tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Sulfatide, a major lipid component of myelin sheath, activates inflammatory responses as an endogenous stimulator in brain-resident immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

New aspects of galectin functionality in nuclei of cultured bone marrow stromal and epidermal cells: biotinylated galectins as tool to detect specific binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Nuclear presence of adhesion-/growth-regulatory galectins in normal/malignant cells of squamous epithelial origin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

GM1 in the nuclear envelope regulates nuclear calcium through association with a nuclear sodium-calcium exchanger

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Dynamics of galectin-3 in the nucleus and cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

New findings on nuclear gangliosides: overview on metabolism and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Differential partitioning and trafficking of GM gangliosides and cholesterol-rich lipid rafts in thymic and splenic CD4 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06479.X

Effects of polyvalency of glycotopes and natural modifications of human blood group ABH/Lewis sugars at the Galβ1-terminated core saccharides on the binding of domain-I of recombinant tandem-repeat-type galectin-4 from rat gastrointestinal tract (G4

21 January 2018

1 reference

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10.1111/J.1749-6632.2012.06479.X

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22524425%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference