(Q38301301)

English

Tumor suppressor p16INK4a--modulator of glycomic profile and galectin-1 expression to increase susceptibility to carbohydrate-dependent induction of anoikis in pancreatic carcinoma cells

scientific article published on 29 May 2007

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Europe PubMed Central

PubMed publication ID

1 September 2017

Tumor suppressor p16INK4a--modulator of glycomic profile and galectin-1 expression to increase susceptibility to carbohydrate-dependent induction of anoikis in pancreatic carcinoma cells (English)

1 reference

Europe PubMed Central

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1 September 2017

pancreatic carcinoma

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based on heuristic

inferred from title

Bertram Wiedenmann

11

object named as

Bertram Wiedenmann

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object named as

Thomas M Gress

13

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object named as

Sabine André

1

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Hans-Joachim Gabius

object named as

Hans-Joachim Gabius

16

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Magnus von Knebel Doeberitz

12

object named as

Magnus von Knebel Doeberitz

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Europe PubMed Central

PubMed publication ID

1 September 2017

author name string

Hugo Sanchez-Ruderisch

2

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1 September 2017

Hiroaki Nakagawa

3

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Europe PubMed Central

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1 September 2017

Malte Buchholz

4

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1 September 2017

Jürgen Kopitz

5

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Europe PubMed Central

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1 September 2017

Pia Forberich

6

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Europe PubMed Central

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1 September 2017

Wolfgang Kemmner

7

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1 September 2017

Corina Böck

8

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1 September 2017

Kisaburo Deguchi

9

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1 September 2017

Katharia M Detjen

10

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1 September 2017

Shin-Ichiro Nishimura

14

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1 September 2017

Stefan Rosewicz

15

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1 September 2017

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publication date

29 May 2007

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Europe PubMed Central

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1 September 2017

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Europe PubMed Central

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1 September 2017

274

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13

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1 September 2017

3233-3256

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Europe PubMed Central

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1 September 2017

Eukaryotic glycosylation: whim of nature or multipurpose tool?

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

A genetic approach to Mammalian glycan function

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

The glycan code of the endoplasmic reticulum: asparagine-linked carbohydrates as protein maturation and quality-control tags

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Cell surface glycans: the why and how of their functionality as biochemical signals in lectin-mediated information transfer

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Malignant cell glycoproteins and glycolipids

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Transcriptional regulation of N-acetylglucosaminyltransferase V by the src oncogene

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

The her-2/neu oncogene stimulates the transcription of N-acetylglucosaminyltransferase V and expression of its cell surface oligosaccharide products

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Ras oncogene induces beta-galactoside alpha2,6-sialyltransferase (ST6Gal I) via a RalGEF-mediated signal to its housekeeping promoter

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Expression of N-acetylglucosaminyltransferase v is associated with prognosis and histology in non-small cell lung cancers

1 reference

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21 January 2018

High expression of N-acetylglucosaminyltransferase V in favorable neuroblastomas: Involvement of its effect on apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

N-acetylglucosaminyltransferase V and beta1-6 branching N-linked oligosaccharides are associated with good prognosis of patients with bladder cancer

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Ras oncogene directs expression of a differentially sialylated, functionally altered β1 integrin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Occurrence of oligosialic acids on integrin alpha 5 subunit and their involvement in cell adhesion to fibronectin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Carbohydrate-carbohydrate binding of ganglioside to integrin alpha(5) modulates alpha(5)beta(1) function.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Galectin-1 interacts with the {alpha}5{beta}1 fibronectin receptor to restrict carcinoma cell growth via induction of p21 and p27.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Galectin-8 binds specific beta1 integrins and induces polarized spreading highlighted by asymmetric lamellipodia in Jurkat T cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

A novel function for the tumor suppressor p16(INK4a): induction of anoikis via upregulation of the alpha(5)beta(1) fibronectin receptor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Down-regulation of beta1,4-galactosyltransferase gene expression by cell-cycle suppressor gene p16.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Rapid cell senescence-associated changes in galactosylation of N-linked oligosaccharides in human lung adenocarcinoma A549 cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Aberrant expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Transcriptional regulation of the human beta-1,4-galactosyltransferase V gene in cancer cells: essential role of transcription factor Sp1

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Elevated beta1,4-galactosyltransferase I in highly metastatic human lung cancer cells. Identification of E1AF as important transcription activator

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Beta1,4-galactosyltransferase V functions as a positive growth regulator in glioma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Down-regulation of the expression of beta1,4-galactosyltransferase V promotes integrin beta1 maturation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Deletion of mouse embryo fibroblast N-acetylglucosaminyltransferase V stimulates alpha5beta1 integrin expression mediated by the protein kinase C signaling pathway

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Regulation on the expression and N-glycosylation of integrins by N-acetylglucosaminyltransferase V

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Galectins bind to the multivalent glycoprotein asialofetuin with enhanced affinities and a gradient of decreasing binding constants

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Glycohistochemistry: the why and how of detection and localization of endogenous lectins.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Chemical biology of the sugar code

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Determination of modulation of ligand properties of synthetic complex-type biantennary N-glycans by introduction of bisecting GlcNAc in silico, in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Introduction of extended LEC14-type branching into core-fucosylated biantennary N-glycan

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

The asialoglycoprotein receptor clears glycoconjugates terminating with sialic acid alpha 2,6GalNAc

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Loss of disialyl Lewis(a), the ligand for lymphocyte inhibitory receptor sialic acid-binding immunoglobulin-like lectin-7 (Siglec-7) associated with increased sialyl Lewis(a) expression on human colon cancers.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Polylactosamine synthesis and branch formation of N-glycans in beta1,4-galactosyltransferase-1-deficient mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Synthesis of poly-N-acetyllactosamine in core 2 branched O-glycans. The requirement of novel beta-1,4-galactosyltransferase IV and beta-1,3-n-acetylglucosaminyltransferase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

The acceptor substrate specificity of human beta4-galactosyltransferase V indicates its potential function in O-glycosylation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Mucin synthesis. Conversion of R1-beta 1-3Gal-R2 to R1-beta 1-3(GlcNAc beta 1-6)Gal-R2 and of R1-beta 1-3GalNAc-R2 to R1-beta 1-3(GlcNAc beta 1-6)GalNAc-R2 by a beta 6-N-acetylglucosaminyltransferase in pig gastric mucosa

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

GalNAc-alpha-O-benzyl inhibits NeuAcalpha2-3 glycosylation and blocks the intracellular transport of apical glycoproteins and mucus in differentiated HT-29 cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Hyposialylation of integrins stimulates the activity of myeloid fibronectin receptors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Cell surface alpha 2,6 sialylation affects adhesion of breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Hypersialylation of beta1 integrins, observed in colon adenocarcinoma, may contribute to cancer progression by up-regulating cell motility

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Mitogenic leukoagglutinin from Phaseolus vulgaris binds to a pentasaccharide unit in N-acetyllactosamine-type glycoprotein glycans

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

alpha2,3/alpha2,6-Sialylation of N-glycans: non-synonymous signals with marked developmental regulation in bovine reproductive tracts

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

A secreted type of beta 1,6-N-acetylglucosaminyltransferase V (GnT-V) induces tumor angiogenesis without mediation of glycosylation: a novel function of GnT-V distinct from the original glycosyltransferase activity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Branching mode in complex-type triantennary N-glycans as regulatory element of their ligand properties

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Comparative cross-linking activities of lactose-specific plant and animal lectins and a natural lactose-binding immunoglobulin G fraction from human serum with asialofetuin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Dimeric galectin-1 binds with high affinity to alpha2,3-sialylated and non-sialylated terminal N-acetyllactosamine units on surface-bound extended glycans.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

The ST6Gal I sialyltransferase selectively modifies N-glycans on CD45 to negatively regulate galectin-1-induced CD45 clustering, phosphatase modulation, and T cell death

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Complex N-glycans are the major ligands for galectin-1, -3, and -8 on Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Unique conformer selection of human growth-regulatory lectin galectin-1 for ganglioside GM1 versus bacterial toxins

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Growth-regulatory human galectin-1: crystallographic characterisation of the structural changes induced by single-site mutations and their impact on the thermodynamics of ligand binding

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Human galectin-2: novel inducer of T cell apoptosis with distinct profile of caspase activation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Interaction profile of galectin-5 with free saccharides and mammalian glycoproteins: probing its fine specificity and the effect of naturally clustered ligand presentation.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Gene expression profiling of mouse postnatal cerebellar development using oligonucleotide microarrays designed to detect differences in glycoconjugate expression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

A focused microarray approach to functional glycomics: transcriptional regulation of the glycome

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Cutting edge: differential requirements for Stat4 in expression of glycosyltransferases responsible for selectin ligand formation in Th1 cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

A crucial role for T-bet in selectin ligand expression in T helper 1 (Th1) cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Galectin-1 is a major receptor for ganglioside GM1, a product of the growth-controlling activity of a cell surface ganglioside sialidase, on human neuroblastoma cells in culture

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Negative regulation of neuroblastoma cell growth by carbohydrate-dependent surface binding of galectin-1 and functional divergence from galectin-3.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Determination of structural and functional overlap/divergence of five proto-type galectins by analysis of the growth-regulatory interaction with ganglioside GM1 in silico and in vitro on human neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Carbohydrate chain of ganglioside GM1 as a ligand: identification of the binding strategies of three 15 mer peptides and their divergence from the binding modes of growth-regulatory galectin-1 and cholera toxin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Effect of 5-azacytidine and galectin-1 on growth and differentiation of the human b lymphoma cell line bl36

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Overexpression of pRB in human pancreatic carcinoma cells: function in chemotherapy-induced apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

FosB gene products trigger cell proliferation and morphological alteration with an increased expression of a novel processed form of galectin-1 in the rat 3Y1 embryo cell line.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Galectin-1(L11A) predicted from a computed galectin-1 farnesyl-binding pocket selectively inhibits Ras-GTP.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Galectin-1 is highly expressed in human gliomas with relevance for modulation of invasion of tumor astrocytes into the brain parenchyma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Galectin-1 modulates human glioblastoma cell migration into the brain through modifications to the actin cytoskeleton and levels of expression of small GTPases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Transfection of 2,6 and 2,3-sialyltransferase genes and GlcNAc-transferase genes into human glioma cell line U-373 MG affects glycoconjugate expression and enhances cell death

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Leukocyte adhesion deficiency II: therapy and genetic defect

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Genetic complementation reveals a novel human congenital disorder of glycosylation of type II, due to inactivation of the Golgi CMP-sialic acid transporter

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Galectin-3 precipitates as a pentamer with synthetic multivalent carbohydrates and forms heterogeneous cross-linked complexes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Galectin-3 augments K-Ras activation and triggers a Ras signal that attenuates ERK but not phosphoinositide 3-kinase activity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Persubstituted cyclodextrin-based glycoclusters as inhibitors of protein-carbohydrate recognition using purified plant and mammalian lectins and wild-type and lectin-gene-transfected tumor cells as targets

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Influence of type of linkage and spacer on the interaction of beta-galactoside-binding proteins with immobilized affinity ligands

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Evidence for stimulation of tumor proliferation in cell lines and histotypic cultures by clinically relevant low doses of the galactoside-binding mistletoe lectin, a component of proprietary extracts

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Lectin localization in human nerve by biochemically defined lectin-binding glycoproteins, neoglycoprotein and lectin-specific antibody

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

New aspects of galectin functionality in nuclei of cultured bone marrow stromal and epidermal cells: biotinylated galectins as tool to detect specific binding sites

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Germ cell survival through carbohydrate-mediated interaction with Sertoli cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Galectins-1 and -3 and their ligands in tumor biology. Non-uniform properties in cell-surface presentation and modulation of adhesion to matrix glycoproteins for various tumor cell lines, in biodistribution of free and liposome-bound galectins and i

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

First demonstration of differential inhibition of lectin binding by synthetic tri- and tetravalent glycoclusters from cross-coupling of rigidified 2-propynyl lactoside.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Glycosyldisulfides from dynamic combinatorial libraries as O-glycoside mimetics for plant and endogenous lectins: their reactivities in solid-phase and cell assays and conformational analysis by molecular dynamics simulations

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Discovery of galectin ligands in fully randomized combinatorial one-bead-one-compound (glyco)peptide libraries

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Plant lectins: occurrence, biochemistry, functions and applications.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Activation of human endothelial cells by tumor necrosis factor-α results in profound changes in the expression of glycosylation-related genes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2007.05851.X

21 January 2018

Identifiers

10.1111/J.1742-4658.2007.05851.X

1 reference

Europe PubMed Central

PubMed publication ID

1 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 September 2017

ResearchGate publication ID

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