(Q38010957)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22595787%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Insights into CNS ageing from animal models of senescence (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22595787%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22595787%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Richard G.A. Faragher

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22595787%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

author name string

Greg Scutt

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22595787%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

language of work or name

English

0 references

publication date

10 May 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22595787%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Neuroscience

1 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22595787%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22595787%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22595787%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

page(s)

435-445

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22595787%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrn3230

1 February 2020

exact match

0 references

cites work

Cognitive impairment in older people: future demand for long-term care services and the associated costs

1 reference

Prevalence of age-associated memory impairment in a randomly selected population from eastern Finland

31 March 2020

1 reference

Insights into the ageing mind: a view from cognitive neuroscience

31 March 2020

1 reference

Neurophysiological correlates of age-related changes in human motor function.

31 March 2020

1 reference

Senescent swallowing: impact, strategies, and interventions

31 March 2020

1 reference

Increased oxidative damage and decreased antioxidant function in aging human substantia nigra compared to striatum: implications for Parkinson's disease.

31 March 2020

1 reference

Life-history connections to rates of aging in terrestrial vertebrates

31 March 2020

1 reference

An analysis of the relationship between metabolism, developmental schedules, and longevity using phylogenetic independent contrasts

31 March 2020

1 reference

Life, death and membrane bilayers

31 March 2020

1 reference

Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms

31 March 2020

1 reference

31 March 2020

Free radicals and aging.

1 reference

Oxidants, oxidative stress and the biology of ageing

31 March 2020

1 reference

31 March 2020

1 reference

Parameters of calcium homeostasis in normal neuronal ageing

31 March 2020

1 reference

Prolonged Ca2+-dependent afterhyperpolarizations in hippocampal neurons of aged rats.

31 March 2020

1 reference

Calcium homeostasis and modulation of synaptic plasticity in the aged brain

31 March 2020

1 reference

Intracellular calcium stores contribute to increased susceptibility to LTD induction during aging

31 March 2020

1 reference

Synaptic plasticity impairment and hypofunction of NMDA receptors induced by glutathione deficit: relevance to schizophrenia

31 March 2020

1 reference

Redox sensitive calcium stores underlie enhanced after hyperpolarization of aged neurons: role for ryanodine receptor mediated calcium signaling

31 March 2020

1 reference

Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons

31 March 2020

1 reference

Aging-dependent alterations in synaptic plasticity and memory in mice that overexpress extracellular superoxide dismutase.

31 March 2020

1 reference

Influence of viral vector-mediated delivery of superoxide dismutase and catalase to the hippocampus on spatial learning and memory during aging

31 March 2020

1 reference

The senescence-associated secretory phenotype: the dark side of tumor suppression

31 March 2020

1 reference

Microarray analysis of senescent vascular smooth muscle cells: A link to atherosclerosis and vascular calcification

31 March 2020

1 reference

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

31 March 2020

1 reference

A transcriptomic analysis of the EK1.Br strain of human fibroblastoid keratocytes: the effects of growth, quiescence and senescence

31 March 2020

1 reference

Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice

31 March 2020

1 reference

New findings in gene knockout, mutant and transgenic mice

31 March 2020

1 reference

Dwarf mice and the ageing process.

31 March 2020

1 reference

Single-gene mutations and healthy ageing in mammals

31 March 2020

1 reference

Genome-environment interactions that modulate aging: powerful targets for drug discovery

31 March 2020

1 reference

Aging-dependent and -independent modulation of associative learning behavior by insulin/insulin-like growth factor-1 signal in Caenorhabditis elegans.

31 March 2020

1 reference

The insulin/PI 3-kinase pathway regulates salt chemotaxis learning in Caenorhabditis elegans

31 March 2020

1 reference

31 March 2020

1 reference

Analgesic, learning and memory and anxiolytic effects of insulin in mice

31 March 2020

1 reference

Insulin receptor substrate 2 is a negative regulator of memory formation

31 March 2020

1 reference

Ribosomal protein S6 kinase 1 signaling regulates mammalian life span

31 March 2020

1 reference

Evolutionary conservation of regulated longevity assurance mechanisms

31 March 2020

1 reference

Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice

31 March 2020

1 reference

Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease

31 March 2020

1 reference

Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

31 March 2020

1 reference

Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments

31 March 2020

1 reference

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

31 March 2020

1 reference

Rapamycin and FK506 induce long-term potentiation by pairing stimulation via an intracellular Ca(2+) signaling mechanism in rat hippocampal CA1 neurons

31 March 2020

1 reference

A transient, neuron-wide form of CREB-mediated long-term facilitation can be stabilized at specific synapses by local protein synthesis.

31 March 2020

1 reference

A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus

31 March 2020

1 reference

Selective pharmacogenetic inhibition of mammalian target of Rapamycin complex I (mTORC1) blocks long-term synaptic plasticity and memory storage

31 March 2020

1 reference

Single-channel activity of the Ca2+-dependent K+ channel is modulated by FK506 and rapamycin.

31 March 2020

1 reference

Systemic inhibition of mammalian target of rapamycin inhibits fear memory reconsolidation

31 March 2020

1 reference

Consolidation and reconsolidation of contextual fear memory requires mammalian target of rapamycin-dependent translation in the dorsal hippocampus

31 March 2020

1 reference

Characterization of the FKBP.rapamycin.FRB ternary complex

31 March 2020

1 reference

Extreme longevity is associated with increased resistance to oxidative stress in Arctica islandica, the longest-living non-colonial animal

31 March 2020

1 reference

Maximum shell size, growth rate, and maturation age correlate with longevity in bivalve molluscs

31 March 2020

1 reference

Masters of longevity: lessons from long-lived bivalves--a mini-review.

31 March 2020

1 reference

Impairment of long-term associative memory in aging snails (Lymnaea stagnalis).

31 March 2020

1 reference

Increased age affects properties characterizing behavioral plasticity in freely behaving Aplysia

31 March 2020

1 reference

Changes in the properties of the modulatory cerebral giant cells contribute to aging in the feeding system of Lymnaea.

31 March 2020

1 reference

Synapse-specific changes in serotonin signalling contribute to age-related changes in the feeding behaviour of the pond snail, Lymnaea.

31 March 2020

1 reference

Potential-dependent Ca Channels of neurons in the mollusc Lymnaea stagnalis in aging: Effect of norepinephrine

31 March 2020

1 reference

The new biology of ageing

31 March 2020

1 reference

PLEIOTROPY, NATURAL SELECTION, AND THE EVOLUTION OF SENESCENCE

31 March 2020

1 reference

The aging process: major risk factor for disease and death

31 March 2020

1 reference

Is the oxidative stress theory of aging dead?

31 March 2020

1 reference

Chemical changes in aging Drosophila melanogaster.

31 March 2020

1 reference

A database of vertebrate longevity records and their relation to other life-history traits

31 March 2020

1 reference

Metformin supplementation and life span in Fischer-344 rats

31 March 2020

1 reference

Effects of age on feeding behavior and chemosensory processing in the pond snail, Lymnaea stagnalis.

31 March 2020

1 reference

Defining wild-type life span in Caenorhabditis elegans

31 March 2020

1 reference

Alterations in intrinsic neuronal excitability during normal aging.

31 March 2020

1 reference

Aging and implicit learning: explorations in contextual cuing.

31 March 2020

1 reference

The effects of aging on the neural basis of implicit associative learning in a probabilistic triplets learning task

31 March 2020

1 reference

Aging and classical conditioning: parallel studies in rabbits and humans

31 March 2020

1 reference

31 March 2020

1 reference

Is procedural memory relatively spared from age effects?

31 March 2020

1 reference

Fischer 344 rats display age-related memory deficits in trace fear conditioning.

31 March 2020

1 reference

The effects of age on eyeblink conditioning in the freely moving Fischer-344 rat.

31 March 2020

1 reference

Context processing in aging: older mice are impaired in renewal of extinguished fear.

31 March 2020

1 reference

Caenorhabditis elegans as a model system to study aging of learning and memory

31 March 2020

1 reference

Impact of aging on hippocampal function: plasticity, network dynamics, and cognition

31 March 2020

1 reference

Patterns of cognitive decline in aged rhesus monkeys.

31 March 2020

1 reference

31 March 2020

1 reference

31 March 2020

1 reference

31 March 2020

1 reference

The neurobiology of memory changes in normal aging

31 March 2020

1 reference

The effects of aging in delay and trace human eyeblink conditioning

31 March 2020

1 reference

Classical conditioning in 3-, 30-, and 45-month-old rabbits: behavioral learning and hippocampal unit activity.

31 March 2020

1 reference

Critical decline in fine motor hand movements in human aging

31 March 2020

1 reference

Prevalence of parkinsonian signs and associated mortality in a community population of older people.

31 March 2020

1 reference

Contributions of age and alcohol consumption to cerebellar integrity, gait and cognition in non-demented very old individuals.

31 March 2020

1 reference

An automated movement assessment panel for upper limb motor functions in rhesus monkeys and humans.

31 March 2020

1 reference

Aged monkeys as a partial model for Parkinson's disease

31 March 2020

1 reference

The effects of aging and oxidative stress on learning behavior in C. elegans

31 March 2020

1 reference

Executive system dysfunction occurs as early as middle-age in the rhesus monkey.

31 March 2020

1 reference

The premature ageing syndromes: insights into the ageing process

31 March 2020

1 reference

31 March 2020

1 reference

The effects of aging on area 46 of the frontal cortex of the rhesus monkey.

31 March 2020

1 reference

Preserved number of entorhinal cortex layer II neurons in aged macaque monkeys.

31 March 2020

1 reference

Conservation of neuron number and size in entorhinal cortex layers II, III, and V/VI of aged primates

31 March 2020

1 reference

Morphological changes in the cerebellar cortex of aging Macaca nemestrina

31 March 2020

1 reference

Neuron number in the parahippocampal region is preserved in aged rats with spatial learning deficits.

31 March 2020

1 reference

Senescent microstructural changes in rat cerebellum

31 March 2020

1 reference

Hippocampal neuron and synaptophysin-positive bouton number in aging C57BL/6 mice.

31 March 2020

1 reference

Atrophy and degeneration of peptidergic neurons and cessation of egg laying in the aging pond snail Lymnaea stagnalis

31 March 2020

1 reference

Life and death of neurons in the aging brain

31 March 2020

1 reference

Morphology of a sensory neuron in Drosophila is abnormal in memory mutants and changes during aging

31 March 2020

1 reference

Excitability and branching of neuroendocrine cells during reproductive senescence

31 March 2020

1 reference

Layer-specific dendritic regression of pyramidal cells with ageing in the human prefrontal cortex.

31 March 2020

1 reference

31 March 2020

1 reference

Selective changes in thin spine density and morphology in monkey prefrontal cortex correlate with aging-related cognitive impairment

31 March 2020

1 reference

The effects of aging on layer 1 in area 46 of prefrontal cortex in the rhesus monkey.

31 March 2020

1 reference

Dying-back of Purkinje cell dendrites with synapse loss in aging rats

31 March 2020

1 reference

Multiple synaptic connections of a single neuron change differentially with age

31 March 2020

1 reference

Solubilization and characterization of thyrotropin-releasing hormone receptors from rat brain

31 March 2020

1 reference

Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease.

31 March 2020

1 reference

Neuropathology of older persons without cognitive impairment from two community-based studies

31 March 2020

1 reference

Alzheimer-type tau pathology in advanced aged nonhuman primate brains harboring substantial amyloid deposition.

31 March 2020

1 reference

Investigation of age-related cognitive decline using mice as a model system: behavioral correlates

31 March 2020

1 reference

Normal aging results in decreased synaptic excitation and increased synaptic inhibition of layer 2/3 pyramidal cells in the monkey prefrontal cortex

31 March 2020

1 reference

Increased action potential firing rates of layer 2/3 pyramidal cells in the prefrontal cortex are significantly related to cognitive performance in aged monkeys.

31 March 2020

1 reference

Senescent changes in a neurobiological model system: Cerebellar Purkinje cell electrophysiology and correlative anatomy

31 March 2020

1 reference

Effect of ageing on CA3 interneuron sAHP and gamma oscillations is activity-dependent

31 March 2020

1 reference

Oxidation of a potassium channel causes progressive sensory function loss during aging

31 March 2020

1 reference

A stereological study of substantia nigra in young and old rhesus monkeys.

31 March 2020

1 reference

31 March 2020

1 reference

Aging of the nigrostriatal system in the squirrel monkey

31 March 2020

1 reference

'Rejuvenation' protects neurons in mouse models of Parkinson's disease

31 March 2020

1 reference

Region-specific downregulation of free intracellular calcium in the aged rat brain

31 March 2020

1 reference

Down-regulation of free intracellular calcium in dissociated brain cells of aged mice and rats.

31 March 2020

1 reference

Age-associated changes of cytoplasmic calcium homeostasis in cerebellar granule neurons in situ: investigation on thin cerebellar slices.

31 March 2020

1 reference

31 March 2020

1 reference

Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store

31 March 2020

1 reference

31 March 2020

1 reference

The effects of aging on N-methyl-D-aspartate receptor subunits in the synaptic membrane and relationships to long-term spatial memory.

31 March 2020

1 reference

Nimodipine decreases calcium action potentials in rabbit hippocampal CA1 neurons in an age-dependent and concentration-dependent manner.

31 March 2020

1 reference

Aging changes in voltage-gated calcium currents in hippocampal CA1 neurons.

31 March 2020

1 reference

31 March 2020

1 reference

Increase in single L-type calcium channels in hippocampal neurons during aging.

31 March 2020

1 reference

High-voltage-activated calcium currents in basal forebrain neurons during aging

31 March 2020

1 reference

Early and simultaneous emergence of multiple hippocampal biomarkers of aging is mediated by Ca2+-induced Ca2+ release.

31 March 2020

1 reference

Modulation of neuronal [Ca2+]i by caffeine is altered with aging.

31 March 2020

1 reference

Calcium homeostasis in aged neurones

31 March 2020

1 reference

31 March 2020

1 reference

Increased excitability of aged rabbit CA1 neurons after trace eyeblink conditioning.

31 March 2020

1 reference

31 March 2020

1 reference

Age-dependent changes in calcium currents and calcium homeostasis in mammalian neurons

31 March 2020

1 reference

12 December 2020

1 reference

12 December 2020

Functional history of two motor neurons and the morphometry of their neuromuscular junctions in the gill of Aplysia: evidence for differential aging

1 reference

12 December 2020

Selective neuronal vulnerability to oxidative stress in the brain

1 reference

12 December 2020

Effects of age on water escape behavior and on repeated acquisition in rats.

1 reference

12 December 2020

Learning capabilities and CA1-prefrontal synaptic plasticity in a mice model of accelerated senescence.

1 reference

12 December 2020

Classical conditioning of the eyeblink response in the delay paradigm in adults aged 18-83 years.

1 reference

12 December 2020

Development of senile plaques. Relationships of neuronal abnormalities and amyloid deposits

1 reference

12 December 2020

Cerebellar volume decline in normal aging, alcoholism, and Korsakoff's syndrome: relation to ataxia

1 reference

12 December 2020

An evaluation of spatial information processing in aged rats.

1 reference

12 December 2020

Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat

1 reference

12 December 2020

[cAMP/PKA signaling underlies age-related memory impairment].

1 reference

12 December 2020

Temperature effects on growth, maturation, and lifespan of the california sea hare (Aplysia californica)

1 reference

12 December 2020

Correlations between physiology and lifespan--two widely ignored problems with comparative studies

1 reference

12 December 2020

Neocortical neuron number in humans: effect of sex and age.

1 reference

12 December 2020