(Q48860624)

English

Increased oxidative damage and decreased antioxidant function in aging human substantia nigra compared to striatum: implications for Parkinson's disease.

scientific article published on 5 October 2011

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scholarly article

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21971758

Increased oxidative damage and decreased antioxidant function in aging human substantia nigra compared to striatum: implications for Parkinson's disease. (English)

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21971758

Parkinson's disease

1 reference

based on heuristic

inferred from title

substantia nigra

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

C Venkateshappa

1

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21971758

G Harish

2

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21971758

Rajeswara Babu Mythri

3

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21971758

Anita Mahadevan

4

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21971758

M M Srinivas Bharath

5

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21971758

S K Shankar

6

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21971758

publication date

5 October 2011

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21971758

Neurochemical Research

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21971758

37

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Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21971758

2

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Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21971758

358-369

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Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21971758

https://scigraph.springernature.com/pub.10.1007/s11064-011-0619-7

0 references

Parkinsonism: onset, progression, and mortality

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Staging of brain pathology related to sporadic Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Parkinson's disease--redox mechanisms

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. The Royal Kings and Queens Parkinson's Disease Research Group

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Chemistry and biochemistry of oxidative stress in neurodegenerative disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Selective Increase of Iron in Substantia Nigra Zona Compacta of Parkinsonian Brains

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Glutathione, iron and Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Protein nitration in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Metabolism of 3-nitrotyrosine induces apoptotic death in dopaminergic cells.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Oxidative and nitrative protein modifications in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Increased nitrotyrosine immunoreactivity in substantia nigra neurons in MPTP treated baboons is blocked by inhibition of neuronal nitric oxide synthase.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Oxidative stress and nitration in neurodegeneration: cause, effect, or association?

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Mitochondrial complex I deficiency in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Neuroinflammation in Alzheimer's disease and Parkinson's disease: are microglia pathogenic in either disorder?

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Proteome analysis of human substantia nigra in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Evaluation of markers of oxidative stress, antioxidant function and astrocytic proliferation in the striatum and frontal cortex of Parkinson's disease brains.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Constitutive expression and functional characterization of mitochondrial glutaredoxin (Grx2) in mouse and human brain

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Selective activation of p38 mitogen-activated protein kinase in dopaminergic neurons of substantia nigra leads to nuclear translocation of p53 in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Absence of age-related changes in nigral dopaminergic neurons of Asian Indians: relevance to lower incidence of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Constitutive expression and localization of cytochrome P-450 1A1 in rat and human brain: presence of a splice variant form in human brain

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Drug metabolism in human brain: high levels of cytochrome P4503A43 in brain and metabolism of anti-anxiety drug alprazolam to its active metabolite

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Expression of GDNF receptors GFRalpha1 and RET is preserved in substantia nigra pars compacta of aging Asian Indians

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Ageing enhances alpha-synuclein, ubiquitin and endoplasmic reticular stress protein expression in the nigral neurons of Asian Indians.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Curcumin treatment alleviates the effects of glutathione depletion in vitro and in vivo: therapeutic implications for Parkinson's disease explained via in silico studies

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Catalase in vitro

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Induction of oxidative stress in Rana ridibunda during recovery from winter hibernation

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Glutathione transferase from rat testis.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Mitochondrial complex I inhibition in Parkinson's disease: how can curcumin protect mitochondria?

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Assessment of mitochondrial oxidative phosphorylation in patient muscle biopsies, lymphoblasts, and transmitochondrial cell lines

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Mitochondrial dysfunction in the limelight of Parkinson's disease pathogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Glutathione peroxidase, glial cells and Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Comparative analysis of LPO products in brain structures of Wistar and OXYS rats of different age.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Regional distributions of thiobarbituric acid-reactive products, activities of enzymes regulating the metabolism of oxygen free radicals, and some of the related enzymes in adult and aged rat brains.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

The origins of oxidant stress in Parkinson's disease and therapeutic strategies.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Selective cell death in neurodegeneration: why are some neurons spared in vulnerable regions?

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Immunocytochemical studies on the basal ganglia and substantia nigra in Parkinson's disease and Huntington's chorea

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Aging produces a specific pattern of striatal dopamine loss: implications for the etiology of idiopathic Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Glutamate induces release of glutathione from cultured rat astrocytes--a possible neuroprotective mechanism?

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Complex I, iron, and ferritin in Parkinson's disease substantia nigra

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Age-related changes in Cu,Zn superoxide dismutase, Se-dependent and -independent glutathione peroxidase and catalase activities in specific areas of rat brain.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Age-related changes in antioxidant enzyme activities are region and organ, as well as sex, selective in the rat

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Glial pathology but absence of apoptotic nigral neurons in long-standing Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Age-related histological changes in the canine substantia nigra

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

The concentration of glial fibrillary acidic protein increases with age in the mouse and rat brain.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Delayed neurodegeneration and early astrogliosis after excitotoxicity to the aged brain.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

The impact of age and gender on the striatal astrocytes activation in murine model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Age as a susceptibility factor in the striatal dopaminergic neurotoxicity observed in the mouse following substituted amphetamine exposure

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Exaggerated astrocyte reactivity after nigrostriatal deafferentation in the aged rat.

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Oestrogen and nigrostriatal dopaminergic neurodegeneration: animal models and clinical reports of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Postmenopausal estrogen use affects risk for Parkinson disease

1 reference

https://api.crossref.org/works/10.1007%2FS11064-011-0619-7

21 January 2018

Altered mitochondrial function, iron metabolism and glutathione levels in Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical analysis of protein stability in human brain collected at different post-mortem intervals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebral enzyme antioxidant system. Influence of aging and phosphatidylcholine

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antigen preservation tests for immunocytochemical detection of cytoskeletal proteins: influence of aldehyde fixatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased protein oxidation in human substantia nigra pars compacta in comparison with basal ganglia and prefrontal cortex measured with an improved dinitrophenylhydrazine assay.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic variations of catecholamine content in hypothalamic nerve cells during the estrous cycle of the rat, with a concomitant study of the substantia nigra

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in dopaminergic neurons of the human substantia nigra during normal aging.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen treatment of dyskinetic disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogen and neuroprotection: higher constitutive expression of glutaredoxin in female mice offers protection against MPTP-mediated neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assays of glutathione peroxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial dysfunction and oxidative stress in aging and neurodegenerative disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial complex I deficiency in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21971758

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11064-011-0619-7

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21971758

1 reference

Europe PubMed Central

16 February 2018

http://europepmc.org/abstract/MED/21971758

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