(Q38010996)

26 August 2017

title

Systems metabolic engineering of microorganisms for natural and non-natural chemicals (English)

1 reference

26 August 2017

Dokyun Na

2

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Sang Yup Lee

object named as

Sang Yup Lee

6

0 references

Joungmin Lee

4

object named as

Joungmin Lee

1 reference

26 August 2017

Jeong Wook Lee

1

1 reference

26 August 2017

Jong Myoung Park

3

1 reference

26 August 2017

Sol Choi

5

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26 August 2017

publication date

17 May 2012

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26 August 2017

published in

Nature Chemical Biology

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26 August 2017

volume

8

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26 August 2017

issue

6

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26 August 2017

page(s)

536-546

1 reference

https://scigraph.springernature.com/pub.10.1038/nchembio.970

26 August 2017

exact match

0 references

cites work

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Engineering a platform for photosynthetic isoprene production in cyanobacteria, using Synechocystis as the model organism

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Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels

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Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol

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Prediction of novel synthetic pathways for the production of desired chemicals

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Computational framework for predictive biodegradation

21 January 2018

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Two approaches for metabolic pathway analysis?

21 January 2018

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Optknock: a bilevel programming framework for identifying gene knockout strategies for microbial strain optimization

21 January 2018

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OptStrain: a computational framework for redesign of microbial production systems.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Metabolic engineering of Escherichia coli for the production of polylactic acid and its copolymers

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Theozymes and compuzymes: theoretical models for biological catalysis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Kemp elimination catalysts by computational enzyme design

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction

21 January 2018

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De novo computational design of retro-aldol enzymes

21 January 2018

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De novo enzyme design using Rosetta3

21 January 2018

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A co-fermentation strategy to consume sugar mixtures effectively

21 January 2018

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An evolved xylose transporter from Zymomonas mobilis enhances sugar transport in Escherichia coli

21 January 2018

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Phosphotransferase system-independent glucose utilization in corynebacterium glutamicum by inositol permeases and glucokinases.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Systems metabolic engineering of Escherichia coli for L-threonine production

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Metabolic engineering of Escherichia coli for the production of L-valine based on transcriptome analysis and in silico gene knockout simulation

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Engineering microbial biofuel tolerance and export using efflux pumps

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Driving forces enable high-titer anaerobic 1-butanol synthesis in Escherichia coli

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Engineered reversal of the β-oxidation cycle for the synthesis of fuels and chemicals

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Stress-induced evolution of Escherichia coli points to original concepts in respiratory cofactor selectivity

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Genetic basis of growth adaptation of Escherichia coli after deletion of pgi, a major metabolic gene

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Improving NADPH availability for natural product biosynthesis in Escherichia coli by metabolic engineering.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Replacing Escherichia coli NAD-dependent glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with a NADP-dependent enzyme from Clostridium acetobutylicum facilitates NADPH dependent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Optimization of a heterologous mevalonate pathway through the use of variant HMG-CoA reductases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Engineered ketol-acid reductoisomerase and alcohol dehydrogenase enable anaerobic 2-methylpropan-1-ol production at theoretical yield in Escherichia coli

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Reversal of coenzyme specificity of 2,3-butanediol dehydrogenase from Saccharomyces cerevisae and in vivo functional analysis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Messy biology and the origins of evolutionary innovations

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Constraints-based genome-scale metabolic simulation for systems metabolic engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Genome-based metabolic engineering of Mannheimia succiniciproducens for succinic acid production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Evolution, genomic analysis, and reconstruction of isobutanol tolerance in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Mathematical modeling of translation initiation for the estimation of its efficiency to computationally design mRNA sequences with desired expression levels in prokaryotes

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Automated design of synthetic ribosome binding sites to control protein expression

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

The zero-sum game of pathway optimization: emerging paradigms for tuning gene expression

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Combining metabolic engineering and metabolic evolution to develop nonrecombinant strains of Escherichia coli C that produce succinate and malate

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Combining metabolic and protein engineering of a terpenoid biosynthetic pathway for overproduction and selectivity control

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Programming cells by multiplex genome engineering and accelerated evolution

21 January 2018

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What is flux balance analysis?

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

A protocol for generating a high-quality genome-scale metabolic reconstruction

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

A genome-scale computational study of the interplay between transcriptional regulation and metabolism

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Thermodynamics-based metabolic flux analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Prediction of metabolic fluxes by incorporating genomic context and flux-converging pattern analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Probabilistic integrative modeling of genome-scale metabolic and regulatory networks in Escherichia coli and Mycobacterium tuberculosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Economics of membrane occupancy and respiro-fermentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Analysis of optimality in natural and perturbed metabolic networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Large-scale identification of genetic design strategies using local search

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

OptForce: an optimization procedure for identifying all genetic manipulations leading to targeted overproductions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

OptORF: Optimal metabolic and regulatory perturbations for metabolic engineering of microbial strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

In silico identification of gene amplification targets for improvement of lycopene production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

EMILiO: a fast algorithm for genome-scale strain design.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Enhancing sesquiterpene production in Saccharomyces cerevisiae through in silico driven metabolic engineering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Application of functional genomics to pathway optimization for increased isoprenoid production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Isoprenoid pathway optimization for Taxol precursor overproduction in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Systems biology meets synthetic biology: a case study of the metabolic effects of synthetic rewiring

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Model-driven engineering of RNA devices to quantitatively program gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Synthetic protein scaffolds provide modular control over metabolic flux.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Use of modular, synthetic scaffolds for improved production of glucaric acid in engineered E. coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Eliminating side products and increasing succinate yields in engineered strains of Escherichia coli C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Metabolic evolution of energy-conserving pathways for succinate production in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Rapid profiling of a microbial genome using mixtures of barcoded oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Biosynthesis of polylactic acid and its copolymers using evolved propionate CoA transferase and PHA synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Metabolic engineering of Escherichia coli for 1-butanol production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

An engineered microbial platform for direct biofuel production from brown macroalgae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Use of catabolite repression mutants for fermentation of sugar mixtures to ethanol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Conversion of proteins into biofuels by engineering nitrogen flux

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Native-sized recombinant spider silk protein produced in metabolically engineered Escherichia coli results in a strong fiber

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Continuous control of the flow in biochemical pathways through 5' untranslated region sequence modifications in mRNA expressed from the broad-host-range promoter Pm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Expanding metabolism for total biosynthesis of the nonnatural amino acid L-homoalanine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Production of L -alanine by metabolically engineered Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Transcriptome analysis of a phenol-producing Pseudomonas putida S12 construct: genetic and physiological basis for improved production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Engineering of solvent-tolerant Pseudomonas putida S12 for bioproduction of phenol from glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

From zero to hero—Design-based systems metabolic engineering of Corynebacterium glutamicum for l-lysine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.970

Systems level engineering of Corynebacterium glutamicum - Reprogramming translational efficiency for superior production

21 January 2018

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Discovery and analysis of novel metabolic pathways for the biosynthesis of industrial chemicals: 3-hydroxypropanoate

21 January 2018

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12 December 2020

The challenges of integrating multi-omic data sets

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Styrene biosynthesis from glucose by engineered E. coli

1 reference

12 December 2020

Metabolic engineering of Escherichia coli for the production of putrescine: a four carbon diamine

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12 December 2020

Metabolic engineering of Escherichia coli for the production of cadaverine: A five carbon diamine

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12 December 2020

Identifiers

DOI

10.1038/NCHEMBIO.970

1 reference

Dimensions Publication ID

26 August 2017

1025152074

0 references

1 reference