(Q38017696)

27 August 2017

title

The interplay between retinoic acid receptor-related orphan receptors and human diseases (English)

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27 August 2017

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Harmit S Ranhotra

1

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27 August 2017

publication date

11 June 2012

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Journal of Receptors and Signal Transduction

27 August 2017

published in

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27 August 2017

volume

32

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27 August 2017

issue

4

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27 August 2017

page(s)

181-189

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International Union of Pharmacology. LXVI. Orphan nuclear receptors

27 August 2017

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Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism

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The orphan nuclear receptor, RORalpha, regulates gene expression that controls lipid metabolism: staggerer (SG/SG) mice are resistant to diet-induced obesity.

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Dynamic patterned expression of orphan nuclear receptor genes RORalpha and RORbeta in developing mouse forebrain

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Retinoic acid receptor-related orphan receptor alpha regulates a subset of cone genes during mouse retinal development

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In vitro and in vivo evidence for orphan nuclear receptor RORalpha function in bone metabolism

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Lymphocyte development and function in the absence of retinoic acid-related orphan receptor alpha.

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Activation of the blue opsin gene in cone photoreceptor development by retinoid-related orphan receptor beta

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Identification of human CYP2C8 as a retinoid-related orphan nuclear receptor target gene

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Binding of ligands and activation of transcription by nuclear receptors.

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The functional significance of nuclear receptor acetylation

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The co-repressor hairless protects RORalpha orphan nuclear receptor from proteasome-mediated degradation

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All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta

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OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells

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Coactivators and nuclear receptor transactivation

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Nuclear receptor coactivators: the key to unlock chromatin

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Transcriptional repression by nuclear hormone receptors

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Mechanism of corepressor binding and release from nuclear hormone receptors.

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Identification of oxysterol 7alpha-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor alpha (RORalpha) (NR1F1) target gene and a functional cross-talk between RORalpha and liver X receptor (NR1H3)

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RORA, a large common fragile site gene, is involved in cellular stress response

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Common fragile sites, extremely large genes, neural development and cancer

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Common human cancer genes discovered by integrated gene-expression analysis

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Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray

21 January 2018

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21 January 2018

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Interactions among the transcription factors Runx1, RORgammat and Foxp3 regulate the differentiation of interleukin 17-producing T cells

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Generation and regulation of human CD4+ IL-17-producing T cells in ovarian cancer

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Hypoxia signalling in cancer and approaches to enforce tumour regression

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The gene encoding human retinoic acid-receptor-related orphan receptor alpha is a target for hypoxia-inducible factor 1.

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Farnesol-induced apoptosis in human lung carcinoma cells is coupled to the endoplasmic reticulum stress response

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Increased ischemia-induced angiogenesis in the staggerer mouse, a mutant of the nuclear receptor Roralpha

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Modulatory role for retinoid-related orphan receptor alpha in allergen-induced lung inflammation.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes.

21 January 2018

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The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

21 January 2018

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T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

21 January 2018

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21 January 2018

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TH17 cells in development: an updated view of their molecular identity and genetic programming

21 January 2018

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Th17 T cells: linking innate and adaptive immunity

21 January 2018

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RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F.

21 January 2018

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Transcriptional oscillation of canonical clock genes in mouse peripheral tissues

21 January 2018

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The crosstalk between physiology and circadian clock proteins

21 January 2018

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Classification of distinct baseline insulin infusion patterns in children and adolescents with type 1 diabetes on continuous subcutaneous insulin infusion therapy

21 January 2018

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Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease

21 January 2018

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Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands

21 January 2018

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Sterol efflux is impaired from macrophage foam cells selectively enriched with 7-ketocholesterol

21 January 2018

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A nuclear receptor-mediated xenobiotic response and its implication in drug metabolism and host protection.

21 January 2018

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Orphan nuclear receptor-mediated xenobiotic regulation in drug metabolism

21 January 2018

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An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

21 January 2018

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SXR, a novel steroid and xenobiotic-sensing nuclear receptor

21 January 2018

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Humanized xenobiotic response in mice expressing nuclear receptor SXR.

21 January 2018

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The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

21 January 2018

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The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

21 January 2018

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The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

21 January 2018

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Vitamin D receptor as an intestinal bile acid sensor

21 January 2018

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Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

21 January 2018

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Fxr(-/-) mice adapt to biliary obstruction by enhanced phase I detoxification and renal elimination of bile acids

21 January 2018

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Activation of LXRs prevents bile acid toxicity and cholestasis in female mice.

21 January 2018

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https://api.crossref.org/works/10.3109%2F10799893.2012.692120

Estrogen deprivation and inhibition of breast cancer growth in vivo through activation of the orphan nuclear receptor liver X receptor

21 January 2018

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10.3109/10799893.2012.692120

21 January 2018

Identifiers

DOI

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27 August 2017

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