(Q38020415)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22718244%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

Understanding the targeting of the RB family proteins by viral oncoproteins to defeat their oncogenic machinery (English)

1 reference

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5 February 2020

2

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5 February 2020

author name string

Emanuele Bellacchio

series ordinal

1

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5 February 2020

publication date

1 February 2013

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22718244%20AND%20SRC:MED&resulttype=core&format=json

Journal of Cellular Physiology

5 February 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22718244%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

volume

228

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5 February 2020

issue

2

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5 February 2020

page(s)

285-291

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Retinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexes

5 February 2020

cites work

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Retinoblastoma protein meets chromatin

21 January 2018

1 reference

The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

21 January 2018

1 reference

Phosphorylation-induced conformational changes in the retinoblastoma protein inhibit E2F transactivation domain binding

21 January 2018

1 reference

DnaJ/hsp40 chaperone domain of SV40 large T antigen promotes efficient viral DNA replication

21 January 2018

1 reference

Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product

21 January 2018

1 reference

Domains A and B in the Rb pocket interact to form a transcriptional repressor motif

21 January 2018

1 reference

Modulation of oncogenic phenotype in human glioma cells by cytomegalovirus IE1-mediated mitogenicity

21 January 2018

1 reference

Pocket proteins and cell cycle control

21 January 2018

1 reference

The role of the J domain of SV40 large T in cellular transformation

21 January 2018

1 reference

SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

21 January 2018

1 reference

The retinoblastoma-susceptibility gene product becomes phosphorylated in multiple stages during cell cycle entry and progression

21 January 2018

1 reference

Three regions of the pRB pocket domain affect its inactivation by human papillomavirus E7 proteins

21 January 2018

1 reference

pRB Contains an E2F1-Specific Binding Domain that Allows E2F1-Induced Apoptosis to Be Regulated Separately from Other E2F Activities

21 January 2018

1 reference

The regulation of E2F by pRB-family proteins

21 January 2018

1 reference

Independent regions of adenovirus E1A are required for binding to and dissociation of E2F-protein complexes

21 January 2018

1 reference

Retinoblastoma family proteins as key targets of the small DNA virus oncoproteins.

21 January 2018

1 reference

Clonal integration of a polyomavirus in human Merkel cell carcinoma

21 January 2018

1 reference

Identification and characterization of small molecule antagonists of pRb inactivation by viral oncoproteins

21 January 2018

1 reference

Cell cycle regulation and neural differentiation

21 January 2018

1 reference

Degradation of the retinoblastoma tumor suppressor by the human papillomavirus type 16 E7 oncoprotein is important for functional inactivation and is separable from proteasomal degradation of E7.

21 January 2018

1 reference

Role of Rb family in the epigenetic definition of chromatin.

21 January 2018

1 reference

Potent anti-tumor effect generated by a novel human papillomavirus (HPV) antagonist peptide reactivating the pRb/E2F pathway

21 January 2018

1 reference

The Rb/E2F pathway: expanding roles and emerging paradigms

21 January 2018

1 reference

Novel mechanisms of E2F induction by BK virus large-T antigen: requirement of both the pRb-binding and the J domains

21 January 2018

1 reference

Destabilization of the retinoblastoma tumor suppressor by human papillomavirus type 16 E7 is not sufficient to overcome cell cycle arrest in human keratinocytes

21 January 2018

1 reference

Mechanisms by which DNA tumor virus oncoproteins target the Rb family of pocket proteins

21 January 2018

1 reference

A cancer derived mutation in the retinoblastoma gene with a distinct defect for LXCXE dependent interactions

21 January 2018

1 reference

An overlapping kinase and phosphatase docking site regulates activity of the retinoblastoma protein

21 January 2018

1 reference

Adenovirus DNA in Guthrie cards from children who develop acute lymphoblastic leukaemia (ALL).

21 January 2018

1 reference

Phosphorylation of retinoblastoma protein by viral protein with cyclin-dependent kinase function.

21 January 2018

1 reference

Identification of distinct roles for separate E1A domains in disruption of E2F complexes

21 January 2018

1 reference

Human cytomegalovirus pp71 stimulates cell cycle progression by inducing the proteasome-dependent degradation of the retinoblastoma family of tumor suppressors

21 January 2018

1 reference

The T/t common exon of simian virus 40, JC, and BK polyomavirus T antigens can functionally replace the J-domain of the Escherichia coli DnaJ molecular chaperone

21 January 2018

1 reference

Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigen

21 January 2018

1 reference

Epstein-Barr virus latent antigen 3C can mediate the degradation of the retinoblastoma protein through an SCF cellular ubiquitin ligase

21 January 2018

1 reference

Cyclin-dependent kinase-like function is shared by the beta- and gamma- subset of the conserved herpesvirus protein kinases

21 January 2018

1 reference

Interactions of SV40 large T antigen and other viral proteins with retinoblastoma tumour suppressor

21 January 2018

1 reference

Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7

21 January 2018

1 reference

Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor

21 January 2018

1 reference

SV40 large T antigen promotes dephosphorylation of p130.

21 January 2018

1 reference

When viral oncoprotein meets tumor suppressor: a structural view

21 January 2018

1 reference

Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor

21 January 2018

1 reference

Structure of the human Papillomavirus E7 oncoprotein and its mechanism for inactivation of the retinoblastoma tumor suppressor

21 January 2018

1 reference

Specificity determinants of recruitment peptides bound to phospho-CDK2/cyclin A

21 January 2018

1 reference

The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T.

21 January 2018

1 reference

Specific enzymatic dephosphorylation of the retinoblastoma protein

21 January 2018

1 reference

Rb family proteins as modulators of gene expression and new aspects regarding the interaction with chromatin remodeling enzymes

21 January 2018

1 reference

The multi-targeted kinase inhibitor sorafenib inhibits human cytomegalovirus replication.

21 January 2018

1 reference

Control of pRB phosphorylation

21 January 2018

1 reference

Retinoblastoma protein partners

21 January 2018

1 reference

E2F: a link between the Rb tumor suppressor protein and viral oncoproteins

21 January 2018

1 reference

Human cytomegalovirus UL97 kinase activity is required for the hyperphosphorylation of retinoblastoma protein and inhibits the formation of nuclear aggresomes

21 January 2018

1 reference

Identification of a growth suppression domain within the retinoblastoma gene product

21 January 2018

1 reference

Domains of the adenovirus E1A protein required for oncogenic activity are also required for dissociation of E2F transcription factor complexes

21 January 2018

1 reference

Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release

21 January 2018

1 reference

Epstein-Barr virus nuclear antigen 3C facilitates G1-S transition by stabilizing and enhancing the function of cyclin D1.

21 January 2018

1 reference

A novel human DnaJ protein, hTid-1, a homolog of the Drosophila tumor suppressor protein Tid56, can interact with the human papillomavirus type 16 E7 oncoprotein

21 January 2018

1 reference

Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A.

21 January 2018

1 reference

The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner

21 January 2018

1 reference

T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus

21 January 2018

1 reference

Molecular determinants for the complex formation between the retinoblastoma protein and LXCXE sequences

21 January 2018

1 reference

Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen.

21 January 2018

1 reference

The molecular chaperone activity of simian virus 40 large T antigen is required to disrupt Rb-E2F family complexes by an ATP-dependent mechanism

21 January 2018

1 reference

Species-specific elements in the large T-antigen J domain are required for cellular transformation and DNA replication by simian virus 40

21 January 2018

1 reference

Sibling rivalry in the E2F family

21 January 2018

1 reference

Maribavir: a novel antiviral agent with activity against cytomegalovirus

21 January 2018

1 reference

Reorganizing the protein space at the Universal Protein Resource (UniProt)

21 January 2018

1 reference

Adenovirus detection in Guthrie cards from paediatric leukaemia cases and controls

21 January 2018

1 reference

Hematopoietic stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family

21 January 2018

1 reference

Direct interaction between the catalytic subunit of Protein Phosphatase 1 and pRb.

21 January 2018

1 reference

Binding to retinoblastoma pocket domain does not alter the inter-domain flexibility of the J domain of SV40 large T antigen

21 January 2018

1 reference

Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation

21 January 2018

1 reference

A bipartite nuclear localization signal in the retinoblastoma gene product and its importance for biological activity

21 January 2018

1 reference

21 January 2018

1 reference