(Q38020632)

30 June 2019

title

Cellular constituents of immune escape within the tumor microenvironment (English)

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30 June 2019

evasion of host immune response

main subject

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2

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30 June 2019

author name string

Sid P Kerkar

series ordinal

1

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30 June 2019

language of work or name

English

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publication date

21 June 2012

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30 June 2019

published in

Cancer Research

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30 June 2019

volume

72

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30 June 2019

issue

13

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30 June 2019

page(s)

3125-3130

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30 June 2019

Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD8+ T cell responses by dysregulating antigen-presenting cell maturation.

cites work

1 reference

12 December 2020

A model for CD8+ CTL tumor immunosurveillance and regulation of tumor escape by CD4 T cells through an effect on quality of CTL

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Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody.

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Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity

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Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells

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Tumor-induced immune dysfunctions caused by myeloid suppressor cells

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The danger model: a renewed sense of self

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Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase

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Inflammation and cancer

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Control of regulatory T cell development by the transcription factor Foxp3

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12 December 2020

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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12 December 2020

Natural versus adaptive regulatory T cells

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12 December 2020

The tumor microenvironment: a critical determinant of neoplastic evolution

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12 December 2020

Fatal attraction: tumors beckon regulatory T cells

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12 December 2020

Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis

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12 December 2020

CD4+ Tregs and immune control

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12 December 2020

Mechanisms and functional significance of tumour-induced dendritic-cell defects

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12 December 2020

CD4+CD25+ T regulatory cells, immunotherapy of cancer, and interleukin-2.

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12 December 2020

Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection.

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12 December 2020

Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells

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12 December 2020

Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Regulatory Cells and T-Cell Anergy in Tumor-Bearing Host

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12 December 2020

The role of stroma in immune recognition and destruction of well-established solid tumors

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12 December 2020

Regulatory T cells, tumour immunity and immunotherapy

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12 December 2020

Dendritic cells and tumor microenvironment: a dangerous liaison

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12 December 2020

Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells

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12 December 2020

Altered macrophage differentiation and immune dysfunction in tumor development

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12 December 2020

Principles of adoptive T cell cancer therapy

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Adoptive cell transfer: a clinical path to effective cancer immunotherapy

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Role of myeloid cells in tumor angiogenesis and growth

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12 December 2020

The role of myeloid cells in the promotion of tumour angiogenesis

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12 December 2020

Myeloid-derived suppressor cells as regulators of the immune system

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12 December 2020

Myeloid-derived suppressor cells: linking inflammation and cancer

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Myeloid-derived suppressor cells in inflammation: uncovering cell subsets with enhanced immunosuppressive functions

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STATs in cancer inflammation and immunity: a leading role for STAT3

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T-cell engineering for cancer immunotherapy

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Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine

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12 December 2020

Development of monocytes, macrophages, and dendritic cells

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Macrophages, innate immunity and cancer: balance, tolerance, and diversity

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PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors

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Adoptive T cell therapy of cancer

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Macrophage diversity enhances tumor progression and metastasis

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Cancer and inflammation: promise for biologic therapy.

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Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

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AACR centennial series: the biology of cancer metastasis: historical perspective

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Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts

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Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13

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Gene therapy using genetically modified lymphocytes targeting VEGFR-2 inhibits the growth of vascularized syngenic tumors in mice

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12 December 2020

Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha

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12 December 2020

Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment

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Immune parameters affecting the efficacy of chemotherapeutic regimens

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12 December 2020

Expansion of immunoregulatory macrophages by granulocyte-macrophage colony-stimulating factor derived from a murine mammary tumor.

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Hallmarks of Cancer: The Next Generation

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Stimulation of immune-suppressive bone marrow cells by colony-stimulating factors

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12 December 2020

Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion

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12 December 2020

The unholy trinity: inflammation, cytokines, and STAT3 shape the cancer microenvironment

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12 December 2020

A dual role for the immune response in a mouse model of inflammation-associated lung cancer

1 reference

12 December 2020

IL-12 release by engineered T cells expressing chimeric antigen receptors can effectively Muster an antigen-independent macrophage response on tumor cells that have shut down tumor antigen expression

1 reference

12 December 2020

Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido.

1 reference

12 December 2020

Novel cancer immunotherapy agents with survival benefit: recent successes and next steps

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12 December 2020

Cancer immunotherapy comes of age

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12 December 2020

IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors.

1 reference

12 December 2020

Local delivery of interleukin-12 using T cells targeting VEGF receptor-2 eradicates multiple vascularized tumors in mice.

1 reference

12 December 2020

Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning

1 reference

12 December 2020

The development of new immunotherapies for the treatment of cancer using interleukin-2. A review

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12 December 2020

Cell interactions in the induction of tolerance: the role of thymic lymphocytes

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12 December 2020

Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells

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12 December 2020

Synergy between T-cell immunity and inhibition of paracrine stimulation causes tumor rejection

1 reference

12 December 2020

The use of gene-modified tumor-infiltrating lymphocytes for cancer therapy

1 reference

12 December 2020

Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells

1 reference

12 December 2020

Dendritic cells and the control of immunity

1 reference

12 December 2020

Apoptotic death of CD8+ T lymphocytes after immunization: induction of a suppressive population of Mac-1+/Gr-1+ cells

1 reference

12 December 2020

10.1158/0008-5472.CAN-11-4094

Identifiers

DOI

1 reference

30 June 2019

release_75t6phzyl5bdbbbbemr2oqjbyu

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/75t6phzyl5bdbbbbemr2oqjbyu

24 November 2022

mapped directly with Wikidata item

PMCID

6327310

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30 June 2019

PubMed ID

22721837

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30 June 2019