(Q50061565)

http://europepmc.org/abstract/MED/22291136

24 February 2018

title

Local delivery of interleukin-12 using T cells targeting VEGF receptor-2 eradicates multiple vascularized tumors in mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6390958&resulttype=core&format=json

13 May 2020

0 references

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6390958&resulttype=core&format=json

13 May 2020

7

Steven A Rosenberg

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6390958&resulttype=core&format=json

13 May 2020

3

Sid P Kerkar

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6390958&resulttype=core&format=json

13 May 2020

Dhanalakshmi Chinnasamy

1

object named as

Dhanalakshmi Chinnasamy

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6390958&resulttype=core&format=json

13 May 2020

author name string

Zhiya Yu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6390958&resulttype=core&format=json

13 May 2020

Ling Zhang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6390958&resulttype=core&format=json

13 May 2020

Richard A Morgan

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6390958&resulttype=core&format=json

13 May 2020

language of work or name

English

0 references

publication date

30 January 2012

1 reference

http://europepmc.org/abstract/MED/22291136

24 February 2018

published in

Clinical Cancer Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6390958&resulttype=core&format=json

13 May 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6390958&resulttype=core&format=json

13 May 2020

issue

6

1 reference

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13 May 2020

page(s)

1672-1683

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6390958&resulttype=core&format=json

The toxicology of interleukin-12: a review

13 May 2020

cites work

1 reference

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A single-chain IL-12 IgG3 antibody fusion protein retains antibody specificity and IL-12 bioactivity and demonstrates antitumor activity.

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IFN-gamma and Fas/FasL are required for the antitumor and antiangiogenic effects of IL-12/pulse IL-2 therapy

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IL-12 augments antigen-dependent proliferation of activated T lymphocytes

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12 December 2020

Tracking angiogenesis induced by skin wounding and contact hypersensitivity using a Vegfr2-luciferase transgenic mouse

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12 December 2020

A strategy for treatment of Epstein-Barr virus-positive Hodgkin's disease by targeting interleukin 12 to the tumor environment using tumor antigen-specific T cells

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12 December 2020

Intratumoral administration of recombinant human interleukin 12 in head and neck squamous cell carcinoma patients elicits a T-helper 1 profile in the locoregional lymph nodes

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12 December 2020

Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis

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12 December 2020

Enhancement of the antiangiogenic activity of interleukin-12 by peptide targeted delivery of the cytokine to alphavbeta3 integrin.

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12 December 2020

Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma

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Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion

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12 December 2020

Activation of vascular endothelial growth factor receptor-2 in bone marrow leads to accumulation of myeloid cells: role of granulocyte-macrophage colony-stimulating factor

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12 December 2020

Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells

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Analysis of tumor-associated stromal cells using SCID GFP transgenic mice: contribution of local and bone marrow-derived host cells.

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12 December 2020

Immune resistance orchestrated by the tumor microenvironment

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12 December 2020

Myeloid and lymphoid dendritic cells and cytotoxic T lymphocytes in peripheral blood of non-small cell lung cancer patient--a pilot study

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12 December 2020

Endogenous IL-12 triggers an antiangiogenic program in melanoma cells.

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12 December 2020

Identification of a New Subset of Myeloid Suppressor Cells in Peripheral Blood of Melanoma Patients With Modulation by a Granulocyte-Macrophage Colony-Stimulation Factor–Based Antitumor Vaccine

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12 December 2020

Bone marrow subsets differentiate into endothelial cells and pericytes contributing to Ewing's tumor vessels

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12 December 2020

The role of myeloid cells in the promotion of tumour angiogenesis

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12 December 2020

Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens

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12 December 2020

Myeloid-derived suppressor cells as regulators of the immune system

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12 December 2020

IL-12 can target human lung adenocarcinoma cells and normal bronchial epithelial cells surrounding tumor lesions

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12 December 2020

Interleukin-12 receptor beta2: from cytokine receptor to gatekeeper gene in human B-cell malignancies

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12 December 2020

Myeloid-derived suppressor cells in inflammation: uncovering cell subsets with enhanced immunosuppressive functions

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12 December 2020

VEGFR2 is selectively expressed by FOXP3high CD4+ Treg.

1 reference

12 December 2020

Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice.

1 reference

12 December 2020

Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts

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12 December 2020

IL-12 initiates tumor rejection via lymphoid tissue-inducer cells bearing the natural cytotoxicity receptor NKp46.

1 reference

12 December 2020

Gene therapy using genetically modified lymphocytes targeting VEGFR-2 inhibits the growth of vascularized syngenic tumors in mice

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12 December 2020

Glioblastoma stem-like cells give rise to tumour endothelium.

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12 December 2020

Pleiotropic stromal effects of vascular endothelial growth factor receptor 2 antibody therapy in renal cell carcinoma models

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12 December 2020

Improving adoptive T cell therapy by targeting and controlling IL-12 expression to the tumor environment

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12 December 2020

Discovery of a linear peptide for improving tumor targeting of gene products and treatment of distal tumors by IL-12 gene therapy

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12 December 2020

The role of interleukin-12 on modulating myeloid-derived suppressor cells, increasing overall survival and reducing metastasis

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12 December 2020

IL-12 release by engineered T cells expressing chimeric antigen receptors can effectively Muster an antigen-independent macrophage response on tumor cells that have shut down tumor antigen expression

1 reference

12 December 2020

IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors.

1 reference

12 December 2020

Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells

1 reference

12 December 2020

IL-12 deaths: explanation and a puzzle

1 reference

12 December 2020

Antitumor and antimetastatic activity of interleukin-12.

1 reference

12 December 2020

Effects of single-dose interleukin-12 exposure on interleukin-12-associated toxicity and interferon-gamma production

1 reference

12 December 2020

Immunobiology of interleukin-12.

1 reference

12 December 2020

Tumor escape from immune recognition: loss of HLA-A2 melanoma cell surface expression is associated with a complex rearrangement of the short arm of chromosome 6.

1 reference

12 December 2020

10.1158/1078-0432.CCR-11-3050

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6390958&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6390958&resulttype=core&format=json

13 May 2020

1 reference