(Q39645986)

13 September 2017

title

IL-12 initiates tumor rejection via lymphoid tissue-inducer cells bearing the natural cytotoxicity receptor NKp46. (English)

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13 September 2017

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5

Burkhard Becher

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13 September 2017

Maya Eisenring

1

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13 September 2017

Johannes vom Berg

series ordinal

2

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13 September 2017

Glen Kristiansen

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3

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13 September 2017

Elisabeth Saller

series ordinal

4

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13 September 2017

language of work or name

English

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publication date

10 October 2010

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13 September 2017

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13 September 2017

volume

11

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13 September 2017

issue

11

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13 September 2017

page(s)

1030-1038

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Interferons, immunity and cancer immunoediting

13 September 2017

cites work

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Collaborative United Kingdom-Australasian study of cancer in patients treated with immunosuppressive drugs

21 January 2018

1 reference

Malignancy after transplantation

21 January 2018

1 reference

IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity

21 January 2018

1 reference

The three Es of cancer immunoediting

21 January 2018

1 reference

Cancer despite immunosurveillance: immunoselection and immunosubversion

21 January 2018

1 reference

Cooperation of Toll-like receptor signals in innate immune defence

21 January 2018

1 reference

Interleukin-12 and the regulation of innate resistance and adaptive immunity

21 January 2018

1 reference

Distinct role of antigen-specific T helper type 1 (Th1) and Th2 cells in tumor eradication in vivo

21 January 2018

1 reference

Effect of interleukin 12 on tumor induction by 3-methylcholanthrene

21 January 2018

1 reference

Interleukin-12: biological properties and clinical application

21 January 2018

1 reference

IL-23 promotes tumour incidence and growth

21 January 2018

1 reference

Antitumor and antimetastatic activity of interleukin 12 against murine tumors

21 January 2018

1 reference

Differential tumor surveillance by natural killer (NK) and NKT cells.

21 January 2018

1 reference

New aspects of natural-killer-cell surveillance and therapy of cancer

21 January 2018

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The contribution of NKT cells, NK cells, and other gamma-chain-dependent non-T non-B cells to IL-12-mediated rejection of tumors.

21 January 2018

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Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense

21 January 2018

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RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells

21 January 2018

1 reference

Influence of the transcription factor RORgammat on the development of NKp46+ cell populations in gut and skin

21 January 2018

1 reference

Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cells

21 January 2018

1 reference

Interleukin-22-producing innate immune cells: new players in mucosal immunity and tissue repair?

21 January 2018

1 reference

Roles for common cytokine receptor gamma-chain-dependent cytokines in the generation, differentiation, and maturation of NK cell precursors and peripheral NK cells in vivo

21 January 2018

1 reference

Regulation of innate and adaptive immune responses by the related cytokines IL-12, IL-23, and IL-27.

21 January 2018

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Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46

21 January 2018

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IL-7 and IL-15 independently program the differentiation of intestinal CD3-NKp46+ cell subsets from Id2-dependent precursors

21 January 2018

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Human NKp44+IL-22+ cells and LTi-like cells constitute a stable RORC+ lineage distinct from conventional natural killer cells

21 January 2018

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Organogenesis of lymphoid tissues

21 January 2018

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An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells

21 January 2018

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Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22

21 January 2018

1 reference

Cutting edge: IL-7 regulates the peripheral pool of adult ROR gamma+ lymphoid tissue inducer cells.

21 January 2018

1 reference

Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy.

21 January 2018

1 reference

Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor

21 January 2018

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Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma

21 January 2018

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Cutting edge: IL-15-independent NK cell response to mouse cytomegalovirus infection

21 January 2018

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Induction of lymphoidlike stroma and immune escape by tumors that express the chemokine CCL21.

21 January 2018

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Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies

21 January 2018

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OX40 ligand and CD30 ligand are expressed on adult but not neonatal CD4+CD3- inducer cells: evidence that IL-7 signals regulate CD30 ligand but not OX40 ligand expression

21 January 2018

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12 December 2020

The anti-tumor activity of IL-12: mechanisms of innate immunity that are model and dose dependent

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12 December 2020

Phase I trial of interleukin-12 plasmid electroporation in patients with metastatic melanoma

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12 December 2020

Transformation of the microvascular system during multistage tumorigenesis

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12 December 2020

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12 December 2020

Fibroblasts genetically engineered to secrete interleukin 12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo.

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12 December 2020

Targeting of lymphotoxin-alpha to the tumor elicits an efficient immune response associated with induction of peripheral lymphoid-like tissue

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12 December 2020

Cloning and expression of murine IL-12

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12 December 2020

Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors

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12 December 2020

Fusion-proteins as biopharmaceuticals--applications and challenges.

1 reference

12 December 2020

Perforin-dependent NK cell cytotoxicity is sufficient for anti-metastatic effect of IL-12

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12 December 2020

Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production

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12 December 2020

IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells

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12 December 2020

Identifiers

DOI

10.1038/NI.1947

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13 September 2017

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