(Q38025278)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22781900%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

New lives for old: evolution of pseudoenzyme function illustrated by iRhoms (English)

1 reference

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7 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22781900%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Matthew Freeman

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22781900%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

author name string

Colin Adrain

series ordinal

1

1 reference

27 August 2017

Matthew Freeman

series ordinal

2

1 reference

27 August 2017

publication date

11 July 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22781900%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Molecular Cell Biology

7 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22781900%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22781900%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22781900%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

page(s)

489-498

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EphB6-null mutation results in compromised T cell function

7 February 2020

cites work

1 reference

Sequence and structural differences between enzyme and nonenzyme homologs

21 January 2018

1 reference

Human and mouse proteases: a comparative genomic approach

31 March 2020

1 reference

Inactive enzyme-homologues find new function in regulatory processes

31 March 2020

1 reference

Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling

31 March 2020

1 reference

Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE

31 March 2020

1 reference

iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS

31 March 2020

1 reference

Evidence of homology between the beta-chain of human haptoglobin and the chymotrypsin family of serine proteases

31 March 2020

1 reference

Covalent structure of human haptoglobin: a serine protease homolog

31 March 2020

1 reference

Model for haptoglobin heavy chain based upon structural homology

31 March 2020

1 reference

Crystal structure of the ectodomain of human transferrin receptor

31 March 2020

1 reference

Eye evolution: common use and independent recruitment of genetic components.

31 March 2020

1 reference

Gene sharing by delta-crystallin and argininosuccinate lyase

31 March 2020

1 reference

The recruitment of crystallins: new functions precede gene duplication.

31 March 2020

1 reference

The protein kinase complement of the human genome

31 March 2020

1 reference

The mouse kinome: discovery and comparative genomics of all mouse protein kinases

31 March 2020

1 reference

Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships

31 March 2020

1 reference

The Degradome database: mammalian proteases and diseases of proteolysis

31 March 2020

1 reference

MEROPS: the database of proteolytic enzymes, their substrates and inhibitors

31 March 2020

1 reference

Regulation of the Jak2 tyrosine kinase by its pseudokinase domain

31 March 2020

1 reference

Crystal structures of mutant monomeric hexokinase I reveal multiple ADP binding sites and conformational changes relevant to allosteric regulation

31 March 2020

1 reference

Cytidine deaminase. The 2.3 A crystal structure of an enzyme: transition-state analog complex

31 March 2020

1 reference

Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases

31 March 2020

1 reference

Rhomboid proteases and their biological functions

31 March 2020

1 reference

Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteases

31 March 2020

1 reference

Activation of EGFR and ERK by rhomboid signaling regulates the consolidation and maintenance of sleep in Drosophila

31 March 2020

1 reference

Road to ruin: targeting proteins for degradation in the endoplasmic reticulum

31 March 2020

1 reference

iRhom2 is required for the secretion of mouse TNFα

31 March 2020

1 reference

RHBDF2 mutations are associated with tylosis, a familial esophageal cancer syndrome

31 March 2020

1 reference

Characterization of a human rhomboid homolog, p100hRho/RHBDF1, which interacts with TGF-alpha family ligands

31 March 2020

1 reference

Human rhomboid family-1 gene silencing causes apoptosis or autophagy to epithelial cancer cells and inhibits xenograft tumor growth

31 March 2020

1 reference

Human rhomboid family-1 gene RHBDF1 participates in GPCR-mediated transactivation of EGFR growth signals in head and neck squamous cancer cells

31 March 2020

1 reference

ADAMs: key components in EGFR signalling and development

31 March 2020

1 reference

Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

31 March 2020

1 reference

A membrane protein required for dislocation of misfolded proteins from the ER

31 March 2020

1 reference

A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

31 March 2020

1 reference

Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant α-1 antitrypsin from the endoplasmic reticulum

31 March 2020

1 reference

Defining human ERAD networks through an integrative mapping strategy

31 March 2020

1 reference

A putative functional variant within the UBAC2 gene is associated with increased risk of Behçet's disease

31 March 2020

1 reference

Replication study confirms the association between UBAC2 and Behçet's disease in two independent Chinese sets of patients and controls

31 March 2020

1 reference

Rhomboid domain containing 2 (RHBDD2): a novel cancer-related gene over-expressed in breast cancer

31 March 2020

1 reference

The rhomboids: a nearly ubiquitous family of intramembrane serine proteases that probably evolved by multiple ancient horizontal gene transfers

31 March 2020

1 reference

Emerging roles of pseudokinases

31 March 2020

1 reference

Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity

31 March 2020

1 reference

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

31 March 2020

1 reference

ErbB receptors: new insights on mechanisms and biology

31 March 2020

1 reference

Pseudokinases-remnants of evolution or key allosteric regulators?

31 March 2020

1 reference

WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II

31 March 2020

1 reference

CASK Functions as a Mg2+-independent neurexin kinase

31 March 2020

1 reference

TAK1-binding protein 1 is a pseudophosphatase.

31 March 2020

1 reference

Gathering STYX: phosphatase-like form predicts functions for unique protein-interaction domains

31 March 2020

1 reference

Mutations in MTMR13, a new pseudophosphatase homologue of MTMR2 and Sbf1, in two families with an autosomal recessive demyelinating form of Charcot-Marie-Tooth disease associated with early-onset glaucoma

31 March 2020

1 reference

Multi-level regulation of myotubularin-related protein-2 phosphatase activity by myotubularin-related protein-13/set-binding factor-2

31 March 2020

1 reference

Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation

31 March 2020

1 reference

TSG101 may be the prototype of a class of dominant negative ubiquitin regulators

31 March 2020

1 reference

Shaping development with ESCRTs

31 March 2020

1 reference

Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding

31 March 2020

1 reference

HIV-1 and Ebola virus encode small peptide motifs that recruit Tsg101 to sites of particle assembly to facilitate egress

31 March 2020

1 reference

The human PDI family: versatility packed into a single fold.

31 March 2020

1 reference

The human protein disulphide isomerase family: substrate interactions and functional properties

31 March 2020

1 reference

Identification of ERp29, an endoplasmic reticulum lumenal protein, as a new member of the thyroglobulin folding complex

31 March 2020

1 reference

ERp29 triggers a conformational change in polyomavirus to stimulate membrane binding

31 March 2020

1 reference

Thiol-mediated protein retention in the endoplasmic reticulum: the role of ERp44

31 March 2020

1 reference

ERp57 is essential for efficient folding of glycoproteins sharing common structural domains

31 March 2020

1 reference

From antibodies to adiponectin: role of ERp44 in sizing and timing protein secretion

31 March 2020

1 reference

Molecular characterization of the principal substrate binding site of the ubiquitous folding catalyst protein disulfide isomerase

31 March 2020

1 reference

Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease

31 March 2020

1 reference

cFLIP regulation of lymphocyte activation and development

31 March 2020

1 reference

Transferrin receptor-like proteins control the degradation of a yeast metal transporter

31 March 2020

1 reference

Coordinating ERK/MAPK signalling through scaffolds and inhibitors

31 March 2020

1 reference

Localization of the serine protease homolog BmSPH-1 in nodules of E. coli-injected Bombyx mori larvae and functional analysis of its role in nodule melanization

31 March 2020

1 reference

Scabies mite inactivated serine protease paralogs inhibit the human complement system.

31 March 2020

1 reference

The Drosophila serine protease homologue Scarface regulates JNK signalling in a negative-feedback loop during epithelial morphogenesis.

31 March 2020

1 reference

The eukaryotic RNA exosome: same scaffold but variable catalytic subunits

31 March 2020

1 reference

Recurrent Emergence of Catalytically Inactive Ornithine Decarboxylase Homologous Forms That Likely Have Regulatory Function

31 March 2020

1 reference

ThnY is a ferredoxin reductase-like iron-sulfur flavoprotein that has evolved to function as a regulator of tetralin biodegradation gene expression

31 March 2020

1 reference

CARD9 versus CARMA1 in innate and adaptive immunity

31 March 2020

1 reference

Role of the MAGUK protein family in synapse formation and function.

31 March 2020

1 reference

Crystal Structure of the Human N-Myc Downstream-regulated Gene 2 Protein Provides Insight into Its Role as a Tumor Suppressor

31 March 2020

1 reference

Identification of a novel class in the alpha/beta hydrolase fold superfamily: the N-myc differentiation-related proteins.

31 March 2020

1 reference

Peptide-N-glycanases and DNA repair proteins, Xp-C/Rad4, are, respectively, active and inactivated enzymes sharing a common transglutaminase fold

31 March 2020

1 reference

Scabies mite inactivated serine protease paralogues are present both internally in the mite gut and externally in feces

31 March 2020

1 reference

12 December 2020

Analysis of a Finnish family confirms RHBDF2 mutations as the underlying factor in tylosis with esophageal cancer

1 reference

12 December 2020

Comparison of the Amino Acid Sequence of Bovine α-Lactalbumin and Hens Egg White Lysozyme

1 reference

12 December 2020

Windbeutel is required for function and correct subcellular localization of the Drosophila patterning protein Pipe.

1 reference

12 December 2020

Chromosome 17q25 genes, RHBDF2 and CYGB, in ovarian cancer

1 reference

12 December 2020

Rational scanning mutagenesis of a protein kinase identifies functional regions involved in catalysis and substrate interactions

1 reference

12 December 2020