(Q38027227)

27 August 2017

Role of microRNAs in gliomagenesis: targeting miRNAs in glioblastoma multiforme therapy (English)

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27 August 2017

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1 reference

Alexandra Nikaki

1

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27 August 2017

Christina Piperi

series ordinal

2

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27 August 2017

Athanasios G Papavassiliou

series ordinal

3

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27 August 2017

language of work or name

English

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publication date

19 July 2012

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Expert Opinion on Investigational Drugs

27 August 2017

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27 August 2017

21

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27 August 2017

10

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27 August 2017

1475-1488

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The 2007 WHO classification of tumours of the central nervous system

27 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Review: molecular pathology in adult high-grade gliomas: from molecular diagnostics to target therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Molecular pathology in adult gliomas: diagnostic, prognostic, and predictive markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Potential therapeutic implications of cancer stem cells in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Long-term survival with glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, methylenetetrahydrofolate reductase allele status, and increased proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Epigenetic mechanisms in glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNA biogenesis: coordinated cropping and dicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Prediction of Associations between microRNAs and Gene Expression in Glioma Biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

miRBase: integrating microRNA annotation and deep-sequencing data

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

The Drosha-DGCR8 complex in primary microRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNAs in brain tumors : a new diagnostic and therapeutic perspective?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNAs in Neural Stem Cells and Neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Rare Drosha splice variants are deficient in microRNA processing but do not affect general microRNA expression in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNAs as regulators of neural stem cell-related pathways in glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNA expression and function in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Emerging functions of microRNAs in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

microRNAs as oncogenes and tumor suppressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Stem cells, cancer, and cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Cancer stem cells in glioblastoma--molecular signaling and therapeutic targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Identification of human brain tumour initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Normal and oncogenic roles for microRNAs in the developing brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNAs and glioblastoma: roles in core signalling pathways and potential clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Mechanisms of type-I- and type-II-interferon-mediated signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

The neuronal microRNA miR-326 acts in a feedback loop with notch and has therapeutic potential against brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Transcriptional activation of microRNA-34a by NF-kappa B in human esophageal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NF-κB/IκBα negative feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNAs in NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Radiogenomic mapping of edema/cellular invasion MRI-phenotypes in glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

A ten-microRNA expression signature predicts survival in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNA and target protein patterns reveal physiopathological features of glioma subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

A developmental taxonomy of glioblastoma defined and maintained by MicroRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Genome-wide expression profiling identifies deregulated miRNAs in malignant astrocytoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Identification and functional characterization of microRNAs involved in the malignant progression of gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorship

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MiR-195, miR-196b, miR-181c, miR-21 expression levels and O-6-methylguanine-DNA methyltransferase methylation status are associated with clinical outcome in glioblastoma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

A polymorphism of microRNA196a genome region was associated with decreased risk of glioma in Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

A functional polymorphism in the pre-miR-146a gene is associated with risk and prognosis in adult glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

A specific miRNA signature in the peripheral blood of glioblastoma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

miR-21 and 221 upregulation and miR-181b downregulation in human grade II-IV astrocytic tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNA-21 targets LRRFIP1 and contributes to VM-26 resistance in glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

The modulation of microRNAs by type I IFN through the activation of signal transducers and activators of transcription 3 in human glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Regulation of p27Kip1 by miRNA 221/222 in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Up-regulation of micro-RNA-221 (miRNA-221; chr Xp11.3) and caspase-3 accompanies down-regulation of the survivin-1 homolog BIRC1 (NAIP) in glioblastoma multiforme (GBM).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Micro-RNA-128 (miRNA-128) down-regulation in glioblastoma targets ARP5 (ANGPTL6), Bmi-1 and E2F-3a, key regulators of brain cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNA-128 inhibits glioma cells proliferation by targeting transcription factor E2F3a

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Ginsenoside Rh2 inhibits glioma cell proliferation by targeting microRNA-128.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MiRNA-451 plays a role as tumor suppressor in human glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Regulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

miR-124a is frequently down-regulated in glioblastoma and is involved in migration and invasion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Pyruvate kinase M2 is a target of the tumor-suppressive microRNA-326 and regulates the survival of glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNA-10b is overexpressed in malignant glioma and associated with tumor invasive factors, uPAR and RhoC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

miR-218 inhibits the invasive ability of glioma cells by direct downregulation of IKK-β.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MiRNA-196 is upregulated in glioblastoma but not in anaplastic astrocytoma and has prognostic significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Extensive modulation of a set of microRNAs in primary glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

microRNA-146b inhibits glioma cell migration and invasion by targeting MMPs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

miR-21: a small multi-faceted RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNA involvement in glioblastoma pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MIR-451 and Imatinib mesylate inhibit tumor growth of Glioblastoma stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Expression of RNA interference triggers from an oncolytic herpes simplex virus results in specific silencing in tumour cells in vitro and tumours in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Co-delivery of as-miR-21 and 5-FU by poly(amidoamine) dendrimer attenuates human glioma cell growth in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Transforming growth factor-beta and Ras regulate the VEGF/VEGF-receptor system during tumor angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

miR-296 regulates growth factor receptor overexpression in angiogenic endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

miR-195, miR-455-3p and miR-10a( *) are implicated in acquired temozolomide resistance in glioblastoma multiforme cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Chromatin-modifying drugs induce miRNA-153 expression to suppress Irs-2 in glioblastoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNA expression profiles in human cancer cells after ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

A miR-21 inhibitor enhances apoptosis and reduces G(2)-M accumulation induced by ionizing radiation in human glioblastoma U251 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Radiation-induced micro-RNA modulation in glioblastoma cells differing in DNA-repair pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Neuroblastoma therapy: what is in the pipeline?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

A functional screen identifies miR-34a as a candidate neuroblastoma tumor suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

miR-34a confers chemosensitivity through modulation of MAGE-A and p53 in medulloblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Identification of microRNAs as potential prognostic markers in ependymoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Differential expression of microRNAs in GH-secreting pituitary adenomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Accurate classification of metastatic brain tumors using a novel microRNA-based test

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Inhibition of cancer stem cell-like properties and reduced chemoradioresistance of glioblastoma using microRNA145 with cationic polyurethane-short branch PEI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

Combinatorial control of suicide gene expression by tissue-specific promoter and microRNA regulation for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.710199

10.1517/13543784.2012.710199

21 January 2018

Identifiers

DOI

1 reference

27 August 2017

1 reference