(Q38029965)

27 August 2017

title

The hunting of targets: challenge in miRNA research (English)

1 reference

27 August 2017

F Akbari Moqadam

1

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27 August 2017

R Pieters

series ordinal

2

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27 August 2017

M L den Boer

series ordinal

3

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27 August 2017

publication date

3 July 2012

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27 August 2017

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27 August 2017

volume

27

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27 August 2017

issue

1

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27 August 2017

page(s)

16-23

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https://scigraph.springernature.com/pub.10.1038/leu.2012.179

27 August 2017

exact match

0 references

cites work

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The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA

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Identification of novel genes coding for small expressed RNAs

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Most mammalian mRNAs are conserved targets of microRNAs

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miR-15 and miR-16 induce apoptosis by targeting BCL2

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mir-29 regulates Mcl-1 protein expression and apoptosis

21 January 2018

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miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements

21 January 2018

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MiRNA-27a controls FBW7/hCDC4-dependent cyclin E degradation and cell cycle progression

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MicroRNA control of lymphocyte differentiation and function

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A microRNA expression signature of human solid tumors defines cancer gene targets

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Reprogramming of miRNA networks in cancer and leukemia

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Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

21 January 2018

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MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.

21 January 2018

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Expression of miR-196b is not exclusively MLL-driven but is especially linked to activation of HOXA genes in pediatric acute lymphoblastic leukemia

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Glucocorticoid-regulated microRNAs and mirtrons in acute lymphoblastic leukemia.

21 January 2018

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MicroRNA characterize genetic diversity and drug resistance in pediatric acute lymphoblastic leukemia

21 January 2018

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Hsa-mir-125b-2 is highly expressed in childhood ETV6/RUNX1 (TEL/AML1) leukemias and confers survival advantage to growth inhibitory signals independent of p53

21 January 2018

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Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters

21 January 2018

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MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb

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Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3.

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Characterization of microRNA expression profiles in normal human tissues

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Posttranscriptional regulation of microRNA biogenesis in animals

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Causes and consequences of microRNA dysregulation in cancer

21 January 2018

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RNA-binding protein Dnd1 inhibits microRNA access to target mRNA

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2012.179

SMAD proteins control DROSHA-mediated microRNA maturation

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2012.179

Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2012.179

MicroRNAs and cancer: profile, profile, profile

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2012.179

Experimental identification of microRNA targets.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2012.179

Desperately seeking microRNA targets

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2012.179

Prediction of mammalian microRNA targets

21 January 2018

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MicroRNAs: target recognition and regulatory functions

21 January 2018

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Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2012.179

MicroRNA targeting specificity in mammals: determinants beyond seed pairing

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2012.179

Mechanism of translational regulation by miR-2 from sites in the 5' untranslated region or the open reading frame

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2012.179

The code within the code: microRNAs target coding regions

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2012.179

Expanding the microRNA targeting code: functional sites with centered pairing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

An alternative mode of microRNA target recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Ratio of miR-196s to HOXC8 messenger RNA correlates with breast cancer cell migration and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Multiple microRNAs modulate p21Cip1/Waf1 expression by directly targeting its 3' untranslated region

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Creating a flexible multiple microRNA expression vector by linking precursor microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

A novel biochemical method to identify target genes of individual microRNAs: identification of a new Caenorhabditis elegans let-7 target

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

The impact of microRNAs on protein output

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Target mRNA abundance dilutes microRNA and siRNA activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

MicroRNA sponges: progress and possibilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Identifying targets of miR-143 using a SILAC-based proteomic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

miR-29a and miR-142-3p downregulation and diagnostic implication in human acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Identification of human microRNA targets from isolated argonaute protein complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

MicroRNA as biomarkers and regulators in B-cell chronic lymphocytic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

A serum circulating miRNA diagnostic test to identify asymptomatic high-risk individuals with early stage lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Experimental strategies for microRNA target identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

The viral and cellular microRNA targetome in lymphoblastoid cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Isolation of microRNA targets using biotinylated synthetic microRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Hepato-specific microRNA-122 facilitates accumulation of newly synthesized miRNA through regulating PRKRA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Capture of microRNA-bound mRNAs identifies the tumor suppressor miR-34a as a regulator of growth factor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Construction of Parallel Analysis of RNA Ends (PARE) libraries for the study of cleaved miRNA targets and the RNA degradome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Circulating microRNAs as novel minimally invasive biomarkers for breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Destabilization of Bcr-Abl/Jak2 Network by a Jak2/Abl Kinase Inhibitor ON044580 Overcomes Drug Resistance in Blast Crisis Chronic Myelogenous Leukemia (CML)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Mammalian microRNAs predominantly act to decrease target mRNA levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

MicroRNA silencing in primates: towards development of novel therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Widespread changes in protein synthesis induced by microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Identification of miRNA targets with stable isotope labeling by amino acids in cell culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Quantitative proteomics identify novel miR-155 target proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Global identification of miR-373-regulated genes in breast cancer by quantitative proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

The inhibition of the highly expressed miR-221 and miR-222 impairs the growth of prostate carcinoma xenografts in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Experimental validation of microRNA targets using a luciferase reporter system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Maturation of microRNA is hormonally regulated by a nuclear receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

MicroRNA-196a is a potential marker of progression during Barrett's metaplasia-dysplasia-invasive adenocarcinoma sequence in esophagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Integrative analysis of microRNA, mRNA and aCGH data reveals asbestos- and histology-related changes in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Knockdown of miR-21 in human breast cancer cell lines inhibits proliferation, in vitro migration and in vivo tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

miR-195, miR-455-3p and miR-10a( *) are implicated in acquired temozolomide resistance in glioblastoma multiforme cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

LNA-mediated microRNA silencing in non-human primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Down-regulation of the cyclin E1 oncogene expression by microRNA-16-1 induces cell cycle arrest in human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

MicroRNA-124a is a key regulator of proliferation and monocyte chemoattractant protein 1 secretion in fibroblast-like synoviocytes from patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Lentivirus-mediated antagomir expression for specific inhibition of miRNA function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

An emerging player in the adaptive immune response: microRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Role of microRNAs in drug-resistant ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

MiR-125b expression affects the proliferation and apoptosis of human glioma cells by targeting Bmf.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

MicroRNA miR-199a-3p regulates cell proliferation and survival by targeting caveolin-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

MicroRNA-143 regulates adipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Mouse microRNA-124 regulates the expression of Hes1 in P19 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

A brain-specific microRNA regulates dendritic spine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Exploration of human miRNA target genes in neuronal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

New meaning in the message: noncoding RNAs and their role in retinal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

MicroRNAs in kidney function and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

MiR-15a and miR-16-1 cluster functions in human leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

MicroRNA-223 reversibly regulates erythroid and megakaryocytic differentiation of K562 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

MicroRNA 223-dependent expression of LMO2 regulates normal erythropoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

MicroRNA fingerprints during human megakaryocytopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Prognostic factors for T1-T2 squamous cell carcinomas of the mobile tongue: A retrospective cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

Identification of plasma microRNA-21 as a biomarker for early detection and chemosensitivity of non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

7 January 2021

Perfect seed pairing is not a generally reliable predictor for miRNA-target interactions

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

7 January 2021

Experimental identification of microRNA targets by immunoprecipitation of Argonaute protein complexes

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

7 January 2021

Circulating miRNAs are correlated with tumor progression in prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

7 January 2021

Diagnostic applications of cell-free and circulating tumor cell-associated miRNAs in cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

7 January 2021

Plasma microRNAs: a potential biomarker for colorectal cancer?

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

7 January 2021

Performing the Labeled microRNA pull-down (LAMP) assay system: an experimental approach for high-throughput identification of microRNA-target mRNAs

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

7 January 2021

miR-34a as part of the resistance network in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.179

7 January 2021

Identifiers

DOI

10.1038/LEU.2012.179

1 reference

Dimensions Publication ID

27 August 2017

1000982367

0 references

1 reference