(Q38034937)

27 August 2017

Influence of type 1 diabetes genes on disease progression: similarities and differences between countries (English)

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27 August 2017

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Jorma Ilonen

2

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author name string

Johanna Lempainen

series ordinal

1

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27 August 2017

1 October 2012

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27 August 2017

Current diabetes report

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27 August 2017

12

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27 August 2017

5

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27 August 2017

447-455

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https://scigraph.springernature.com/pub.10.1007/s11892-012-0310-7

27 August 2017

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cites work

Natural course of preclinical type 1 diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

HLA class I and genetic susceptibility to type 1 diabetes: results from the Type 1 Diabetes Genetics Consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Human leukocyte antigen class I B and C loci contribute to Type 1 Diabetes (T1D) susceptibility and age at T1D onset

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Genetics of type 1 diabetes: what's next?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Etiology of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Genetic analysis of adult-onset autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Insulin autoantibodies and high titre islet cell antibodies are preferentially associated with the HLA DQA1*0301-DQB1*0302 haplotype at clinical type 1 (insulin-dependent) diabetes mellitus before age 10 years, but not at onset between age 10 and 40

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

The type 1 diabetes - HLA susceptibility interactome--identification of HLA genotype-specific disease genes for type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Predictive characteristics of diabetes-associated autoantibodies among children with HLA-conferred disease susceptibility in the general population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

A comparison of the prevalence of islet autoantibodies in children from two countries with differing incidence of diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Signs of beta-cell autoimmunity in nondiabetic schoolchildren: a comparison between Russian Karelia with a low incidence of type 1 diabetes and Finland with a high incidence rate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the diabetes prevention trial-type 1 (DPT-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

The HLA class I A locus affects susceptibility to type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Do non-HLA genes influence development of persistent islet autoimmunity and type 1 diabetes in children with high-risk HLA-DR,DQ genotypes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

PTPN22: setting thresholds for autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Genetic variation in PTPN22 corresponds to altered function of T and B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Reduced CD4+T cell activation in children with type 1 diabetes carrying the PTPN22/Lyp 620Trp variant

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Why is PTPN22 a good candidate susceptibility gene for autoimmune disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Residual insulin secretion at diagnosis of type 1 diabetes is independently associated with both, age of onset and HLA genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

The PTPN22 C1858T gene variant is associated with proinsulin in new-onset type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Enterovirus infection and type 1 diabetes mellitus: systematic review and meta-analysis of observational molecular studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Remapping the insulin gene/IDDM2 locus in type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Central and peripheral autoantigen presentation in immune tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

CTLA-4 gene polymorphisms and susceptibility to type 1 diabetes mellitus: a HuGE Review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

CTLA-4 gene polymorphism at position 49 in exon 1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Temporal changes in the frequencies of HLA genotypes in patients with Type 1 diabetes--indication of an increased environmental pressure?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Interplay between PTPN22 C1858T polymorphism and cow's milk formula exposure in type 1 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Does the relative risk for type 1 diabetes conferred by HLA-DQ, INS, and PTPN22 polymorphisms vary with maternal age, birth weight, or cesarean section?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Cesarean section and interferon-induced helicase gene polymorphisms combine to increase childhood type 1 diabetes risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Shared and distinct genetic variants in type 1 diabetes and celiac disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

Association of Non-HLA Genes With Type 1 Diabetes Autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

21 January 2018

12 December 2020

The effect of HLA class II, insulin and CTLA4 gene regions on the development of humoral beta cell autoimmunity

1 reference

https://api.crossref.org/works/10.1007%2FS11892-012-0310-7

HLA-DR4 subtype and -B alleles in DQB1*0302-positive haplotypes associated with IDDM. The Childhood Diabetes in Finland Study Group

21 January 2018

1 reference

12 December 2020

The Karlsburg type 1 diabetes risk study of a normal schoolchild population: association of beta-cell autoantibodies and human leukocyte antigen-DQB1 alleles in antibody-positive individuals

1 reference

12 December 2020

HLA genes associated with autoimmunity and progression to disease in type 1 diabetes

1 reference

12 December 2020

Disease-associated autoantibodies and HLA-DQB1 genotypes in children with newly diagnosed insulin-dependent diabetes mellitus (IDDM). The Childhood Diabetes in Finland Study Group

1 reference

12 December 2020

HLA-associated insulin autoantibody formation in newly diagnosed type I diabetic patients

1 reference

12 December 2020

Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB Study

1 reference

12 December 2020

Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups

1 reference

12 December 2020

IDDM2/insulin VNTR modifies risk conferred by IDDM1/HLA for development of Type 1 diabetes and associated autoimmunity.

1 reference

12 December 2020

Autoimmune polyglandular syndromes

1 reference

12 December 2020

Dynamics of diabetes-associated autoantibodies in young children with human leukocyte antigen-conferred risk of type 1 diabetes recruited from the general population

1 reference

12 December 2020

Residual beta-cell function and HLA-A24 in IDDM. Markers of glycemic control and subsequent development of diabetic retinopathy

1 reference

12 December 2020

The rising incidence of childhood type 1 diabetes and reduced contribution of high-risk HLA haplotypes

1 reference

12 December 2020

The role of HLA class II genes in insulin-dependent diabetes mellitus: molecular analysis of 180 Caucasian, multiplex families

1 reference

12 December 2020

A Polymorphic Locus Near the Human Insulin Gene Is Associated with Insulin-dependent Diabetes Melliitus

1 reference

12 December 2020

Association of non-HLA genes with type 1 diabetes autoimmunity

1 reference

12 December 2020

Effect of the PTPN22 and INS risk genotypes on the progression to clinical type 1 diabetes after the initiation of β-cell autoimmunity

1 reference

12 December 2020

Risk of Diabetic Nephropathy in Type 1 Diabetes Is Associated With Functional Polymorphisms in RANTES Receptor Gene (CCR5): A Sex-Specific Effect

1 reference

12 December 2020

Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes

1 reference

12 December 2020

Signs of beta-cell autoimmunity and HLA-defined diabetes susceptibility in the Finnish population: the sib cohort from the Type 1 Diabetes Prediction and Prevention Study

1 reference

12 December 2020

Association of HLA-A24 with complete beta-cell destruction in IDDM

1 reference

12 December 2020

Progression to diabetes in relatives with islet autoantibodies. Is it inevitable?

1 reference

12 December 2020

Analysis of families at risk for insulin-dependent diabetes mellitus reveals that HLA antigens influence progression to clinical disease.

1 reference

12 December 2020

Effect of HLA class I and class II alleles on progression from autoantibody positivity to overt type 1 diabetes in children with risk-associated class II genotypes

1 reference

12 December 2020

10.1007/S11892-012-0310-7

Identifiers

DOI

1 reference

PubMed ID

22895852

Dimensions Publication ID

27 August 2017

0 references

1 reference

PubMed ID

22895852